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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12158 scientific papers returned from the database with the search filters currently being used below.

Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish

Authors:
Zhang C, Zhang Q, Wang F, Liu Q
Citation:
Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15
Epub:
Not Epub
Abstract:
Proteomic analysis of the mouse photoreceptor sensory cilium identified a set of cilia proteins, including Poc1 centriolar...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X15301364
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang C, Zhang Q, Wang F, Liu Q. Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish. Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15.

Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling

Authors:
Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q
Citation:
Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signaling plays essential roles in animal development and tissue homeostasis, and its misregulation causes...
Link:
https://www.cell.com/developmental-cell/fulltext/S1534-5807(15)00352-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q. Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling. Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25.

Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease

Authors:
Deveau AP, Forrester AM, Coombs AJ, Wagner GS, Grabher C, Chute IC, Léger D, Mingay M, Alexe G, Rajan V, Liwski R, Hirst M, Steigmaier K, Lewis SM, Look AT, Berman JN
Citation:
Leukemia. 2015 Oct;29(10):2086-97. doi: 10.1038/leu.2015.126. Epub 2015 May 28
Epub:
Not Epub
Abstract:
Acute myeloid leukemia (AML) occurs when multiple genetic aberrations alter white blood cell development, leading to...
Link:
https://www.nature.com/articles/leu2015126
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deveau AP, Forrester AM, Coombs AJ, Wagner GS, Grabher C, Chute IC, Léger D, Mingay M, Alexe G, Rajan V, Liwski R, Hirst M, Steigmaier K, Lewis SM, Look AT, Berman JN. Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease. Leukemia. 2015 Oct;29(10):2086-97. doi: 10.1038/leu.2015.126. Epub 2015 May 28.

Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish

Authors:
Kung TS, Richardson JR, Cooper KR, White LA
Citation:
Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24
Epub:
Not Epub
Abstract:
Pyrethroids are commonly used insecticides that are considered to pose little risk to human health. However, there is an...
Link:
https://academic.oup.com/toxsci/article/146/2/235/1654737
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kung TS, Richardson JR, Cooper KR, White LA. Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish. Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24.

Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly

Authors:
Li J, Yue Y, Dong X, Jia W, Li K, Liang D, Dong Z, Wang X, Nan X, Zhang Q, Zhao Q
Citation:
J Biol Chem. 2015 Apr 17;290(16):10216-28. doi: 10.1074/jbc.M114.612572. Epub 2015 Feb 27
Epub:
Not Epub
Abstract:
Foxc1a is a member of the forkhead transcription factors. It plays an essential role in zebrafish somitogenesis. However,...
Link:
https://www.jbc.org/content/290/16/10216.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Yue Y, Dong X, Jia W, Li K, Liang D, Dong Z, Wang X, Nan X, Zhang Q, Zhao Q. Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly. J Biol Chem. 2015 Apr 17;290(16):10216-28. doi: 10.1074/jbc.M114.612572. Epub 2015 Feb 27.

Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells

Authors:
Muñoz R, Edwards-Faret G, Moreno M, Zuñiga N, Cline H, Larraín J
Citation:
Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19
Epub:
Not Epub
Abstract:
Spinal cord regeneration is very inefficient in humans, causing paraplegia and quadriplegia. Studying model organisms that can...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160615001220
Delivery Method:
injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Muñoz R, Edwards-Faret G, Moreno M, Zuñiga N, Cline H, Larraín J. Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells. Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19.

Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model

Authors:
Pfirrmann T, Emmerich D, Ruokonen P, Quandt D, Buchen R, Fischer-Zirnsak B, Hecht J, Krawitz P, Meyer P, Klopocki E, Stricker S, Lausch E, Seliger B, Hollemann T, Reinhard T, Auw-Haedrich C, Zabel B, Hoffmann K, Villavicencio-Lorini P
Citation:
Hum Mol Genet. 2015 Jun 1;24(11):3119-32. doi: 10.1093/hmg/ddv063. Epub 2015 Feb 23
Epub:
Not Epub
Abstract:
Chordin-Like 1 (CHRDL1) mutations cause non-syndromic X-linked megalocornea (XMC) characterized by enlarged anterior eye...
Link:
https://academic.oup.com/hmg/article/24/11/3119/720148
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pfirrmann T, Emmerich D, Ruokonen P, Quandt D, Buchen R, Fischer-Zirnsak B, Hecht J, Krawitz P, Meyer P, Klopocki E, Stricker S, Lausch E, Seliger B, Hollemann T, Reinhard T, Auw-Haedrich C, Zabel B, Hoffmann K, Villavicencio-Lorini P. Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. Hum Mol Genet. 2015 Jun 1;24(11):3119-32. doi: 10.1093/hmg/ddv063. Epub 2015 Feb 23.

Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway

Authors:
Liu ZF, Ji JF, Jiang XF, Shao T, Fan DD, Jiang XH, Lin AF, Xiang LX, Shao JZ
Citation:
FASEB J. 2020 Apr 14. doi: 10.1096/fj.201902833R. [Epub ahead of print]
Epub:
Yes
Abstract:
Cyclic GMP-AMP synthase (cGAS) is one of the most-characterized cytoplasmic DNA sensors in humans and other mammals. However,...
Link:
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201902833R
Citation Extract:
Liu ZF, Ji JF, Jiang XF, Shao T, Fan DD, Jiang XH, Lin AF, Xiang LX, Shao JZ. Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway. FASEB J. 2020 Apr 14. doi: 10.1096/fj.201902833R. [Epub ahead of print].

Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition

Authors:
Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S
Citation:
J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11
Epub:
Not Epub
Abstract:
UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase tags newly synthesized lysosomal enzymes with mannose 6-phosphate...
Link:
https://www.jbc.org/content/290/5/3045.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S. Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition. J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11.

RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells

Authors:
Chen HY, Liu W, Wu SY, Chiou PP, Li YH, Chen YC, Lin GH, Lu MW, Wu JL
Citation:
Fish Shellfish Immunol. 2015 Apr;43(2):427-35. doi: 10.1016/j.fsi.2015.01.012. Epub 2015 Jan 26
Epub:
Not Epub
Abstract:
The type I interferon (IFN) response has been shown to be crucial for the survival of zebrafish larvae infected with nervous...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1050464815000133
Organism or Cell Type:
cell culture: zebrafish
Citation Extract:
Chen HY, Liu W, Wu SY, Chiou PP, Li YH, Chen YC, Lin GH, Lu MW, Wu JL. RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells. Fish Shellfish Immunol. 2015 Apr;43(2):427-35. doi: 10.1016/j.fsi.2015.01.012. Epub 2015 Jan 26.

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