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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12158 scientific papers returned from the database with the search filters currently being used below.
There are 12158 scientific papers returned from the database with the search filters currently being used below.
Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish
Citation:
Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15 Epub:
Not Epub Abstract:
Proteomic analysis of the mouse photoreceptor sensory cilium identified a set of cilia proteins, including Poc1 centriolar... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang C, Zhang Q, Wang F, Liu Q. Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish. Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15. |
Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling
Citation:
Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25 Epub:
Not Epub Abstract:
Hedgehog (Hh) signaling plays essential roles in animal development and tissue homeostasis, and its misregulation causes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q. Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling. Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25. |
Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease
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Leukemia. 2015 Oct;29(10):2086-97. doi: 10.1038/leu.2015.126. Epub 2015 May 28 Epub:
Not Epub Abstract:
Acute myeloid leukemia (AML) occurs when multiple genetic aberrations alter white blood cell development, leading to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Deveau AP, Forrester AM, Coombs AJ, Wagner GS, Grabher C, Chute IC, Léger D, Mingay M, Alexe G, Rajan V, Liwski R, Hirst M, Steigmaier K, Lewis SM, Look AT, Berman JN. Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease. Leukemia. 2015 Oct;29(10):2086-97. doi: 10.1038/leu.2015.126. Epub 2015 May 28. |
Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish
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Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24 Epub:
Not Epub Abstract:
Pyrethroids are commonly used insecticides that are considered to pose little risk to human health. However, there is an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kung TS, Richardson JR, Cooper KR, White LA. Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish. Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24. |
Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly
Citation:
J Biol Chem. 2015 Apr 17;290(16):10216-28. doi: 10.1074/jbc.M114.612572. Epub 2015 Feb 27 Epub:
Not Epub Abstract:
Foxc1a is a member of the forkhead transcription factors. It plays an essential role in zebrafish somitogenesis. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li J, Yue Y, Dong X, Jia W, Li K, Liang D, Dong Z, Wang X, Nan X, Zhang Q, Zhao Q. Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly. J Biol Chem. 2015 Apr 17;290(16):10216-28. doi: 10.1074/jbc.M114.612572. Epub 2015 Feb 27. |
Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells
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Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19 Epub:
Not Epub Abstract:
Spinal cord regeneration is very inefficient in humans, causing paraplegia and quadriplegia. Studying model organisms that can... Delivery Method:
injection then electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Muñoz R, Edwards-Faret G, Moreno M, Zuñiga N, Cline H, Larraín J. Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells. Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19. |
Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model
Citation:
Hum Mol Genet. 2015 Jun 1;24(11):3119-32. doi: 10.1093/hmg/ddv063. Epub 2015 Feb 23 Epub:
Not Epub Abstract:
Chordin-Like 1 (CHRDL1) mutations cause non-syndromic X-linked megalocornea (XMC) characterized by enlarged anterior eye... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Pfirrmann T, Emmerich D, Ruokonen P, Quandt D, Buchen R, Fischer-Zirnsak B, Hecht J, Krawitz P, Meyer P, Klopocki E, Stricker S, Lausch E, Seliger B, Hollemann T, Reinhard T, Auw-Haedrich C, Zabel B, Hoffmann K, Villavicencio-Lorini P. Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. Hum Mol Genet. 2015 Jun 1;24(11):3119-32. doi: 10.1093/hmg/ddv063. Epub 2015 Feb 23. |
Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway
Citation:
FASEB J. 2020 Apr 14. doi: 10.1096/fj.201902833R. [Epub ahead of print] Epub:
Yes Abstract:
Cyclic GMP-AMP synthase (cGAS) is one of the most-characterized cytoplasmic DNA sensors in humans and other mammals. However,... Citation Extract: Liu ZF, Ji JF, Jiang XF, Shao T, Fan DD, Jiang XH, Lin AF, Xiang LX, Shao JZ. Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway. FASEB J. 2020 Apr 14. doi: 10.1096/fj.201902833R. [Epub ahead of print]. |
Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition
Citation:
J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11 Epub:
Not Epub Abstract:
UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase tags newly synthesized lysosomal enzymes with mannose 6-phosphate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S. Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition. J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11. |
RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells
Citation:
Fish Shellfish Immunol. 2015 Apr;43(2):427-35. doi: 10.1016/j.fsi.2015.01.012. Epub 2015 Jan 26 Epub:
Not Epub Abstract:
The type I interferon (IFN) response has been shown to be crucial for the survival of zebrafish larvae infected with nervous... Organism or Cell Type:
cell culture: zebrafish Citation Extract: Chen HY, Liu W, Wu SY, Chiou PP, Li YH, Chen YC, Lin GH, Lu MW, Wu JL. RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells. Fish Shellfish Immunol. 2015 Apr;43(2):427-35. doi: 10.1016/j.fsi.2015.01.012. Epub 2015 Jan 26. |