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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Esco2 regulates cx43 expression during skeletal regeneration in the zebrafish fin
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Citation:
Dev Dyn. 2016 Jan;245(1):7-21. doi: 10.1002/dvdy.24354. Epub 2015 Nov 25 Epub:
Not Epub Abstract:
Background: Roberts syndrome (RBS) is a rare genetic disorder characterized by craniofacial abnormalities, limb malformation,... Delivery Method:
injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Banerji R, Eble DM, Iovine MK, Skibbens RV. Esco2 regulates cx43 expression during skeletal regeneration in the zebrafish fin. Dev Dyn. 2016 Jan;245(1):7-21. doi: 10.1002/dvdy.24354. Epub 2015 Nov 25. |
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling
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Citation:
J Biol Chem. 2015 Sep 4;290(36):21925-38. doi: 10.1074/jbc.M115.644864. Epub 2015 Jul 20 Epub:
Not Epub Abstract:
The neural crest (NC) is a transient, migratory cell population that differentiates into a large variety of tissues including... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wang C, Kam RK, Shi W, Xia Y, Chen X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H. The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling. J Biol Chem. 2015 Sep 4;290(36):21925-38. doi: 10.1074/jbc.M115.644864. Epub 2015 Jul 20. |
G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus
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Citation:
Dev Biol. 2015 Nov 1;407(1):131-44. doi: 10.1016/j.ydbio.2015.08.001. Epub 2015 Aug 3 Epub:
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Patterning of the vertebrate anterior–posterior axis is regulated by the coordinated action of growth factors whose effects can... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Miyagi A, Negishi T, Yamamoto TS, Ueno N. G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus. Dev Biol. 2015 Nov 1;407(1):131-44. doi: 10.1016/j.ydbio.2015.08.001. Epub 2015 Aug 3. |
TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets
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Citation:
bioRxiv. 2020:[preprint]. doi:10.1101/2020.04.15.042085 Epub:
Not Epub Abstract:
In December 2019, a novel coronavirus named SARS-CoV-2 first reported in Wuhan, China, emerged and rapidly spread to numerous... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Calu-3 Citation Extract: Bestle D, Heindl MR, Limburg H, Van TVL, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Becker S, Klenk H-D, Garten W, Steinmetzer T, Bottcher-Friebertshauser E. TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets. bioRxiv. 2020:[preprint]. doi:10.1101/2020.04.15.042085 . |
Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish
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Citation:
Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15 Epub:
Not Epub Abstract:
Proteomic analysis of the mouse photoreceptor sensory cilium identified a set of cilia proteins, including Poc1 centriolar... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang C, Zhang Q, Wang F, Liu Q. Knockdown of poc1b causes abnormal photoreceptor sensory cilium and vision impairment in zebrafish. Biochem Biophys Res Commun. 2015 Oct 2;465(4):651-7. doi: 10.1016/j.bbrc.2015.06.083. Epub 2015 Jul 15. |
Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling
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Citation:
Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25 Epub:
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Hedgehog (Hh) signaling plays essential roles in animal development and tissue homeostasis, and its misregulation causes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q. Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling. Dev Cell. 2015 Jul 6;34(1):58-72. doi: 10.1016/j.devcel.2015.05.016. Epub 2015 Jun 25. |
Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease
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Leukemia. 2015 Oct;29(10):2086-97. doi: 10.1038/leu.2015.126. Epub 2015 May 28 Epub:
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Acute myeloid leukemia (AML) occurs when multiple genetic aberrations alter white blood cell development, leading to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Deveau AP, Forrester AM, Coombs AJ, Wagner GS, Grabher C, Chute IC, Léger D, Mingay M, Alexe G, Rajan V, Liwski R, Hirst M, Steigmaier K, Lewis SM, Look AT, Berman JN. Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease. Leukemia. 2015 Oct;29(10):2086-97. doi: 10.1038/leu.2015.126. Epub 2015 May 28. |
Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish
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Citation:
Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24 Epub:
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Pyrethroids are commonly used insecticides that are considered to pose little risk to human health. However, there is an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kung TS, Richardson JR, Cooper KR, White LA. Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish. Toxicol Sci. 2015 Aug;146(2):235-43. doi: 10.1093/toxsci/kfv087. Epub 2015 Apr 24. |
Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly
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Citation:
J Biol Chem. 2015 Apr 17;290(16):10216-28. doi: 10.1074/jbc.M114.612572. Epub 2015 Feb 27 Epub:
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Foxc1a is a member of the forkhead transcription factors. It plays an essential role in zebrafish somitogenesis. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li J, Yue Y, Dong X, Jia W, Li K, Liang D, Dong Z, Wang X, Nan X, Zhang Q, Zhao Q. Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly. J Biol Chem. 2015 Apr 17;290(16):10216-28. doi: 10.1074/jbc.M114.612572. Epub 2015 Feb 27. |
Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells
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Citation:
Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19 Epub:
Not Epub Abstract:
Spinal cord regeneration is very inefficient in humans, causing paraplegia and quadriplegia. Studying model organisms that can... Delivery Method:
injection then electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Muñoz R, Edwards-Faret G, Moreno M, Zuñiga N, Cline H, Larraín J. Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells. Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19. |