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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Functional characterization of Neurofilament Light b splicing and misbalance in zebrafish
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.27.064063 Epub:
Not Epub Abstract:
Neurofilaments (NFs), a major cytoskeletal component of motor neurons, play a key role in their differentiation, establishment... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demy DL, Campanari M-L, Munoz-Ruiz R,Durham HD, Gentil B, Kabashi E. Functional characterization of Neurofilament Light b splicing and misbalance in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.27.064063. |
Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis
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Citation:
Development. 2020;147(8):[Epub] doi:10.1242/dev.184689 Epub:
Not Epub Abstract:
Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Osborn DPS, Li K, Cutty SJ, Nelson AC, Wardle FC, Hinits Y, Hughes SM. Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis. Development. 2020;147(8):[Epub] doi:10.1242/dev.184689. |
Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function
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Citation:
Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078 Epub:
Not Epub Abstract:
Photoactivatable cyclic caged morpholino oligomers (ccMOs) represent a promising tool to selectively regulate gene expression... Citation Extract: Deodato D, Dore TM. Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function. Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078. |
A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly
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Citation:
Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print] Epub:
Yes Abstract:
Mitochondrial ribosomal protein large 24 (MRPL24) is 1 of the 82 protein components of mitochondrial ribosomes, playing an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nottia MD, Marchese M, Verrigni D, Mutti C, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R. A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly. Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print]. |
Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes
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Citation:
Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322 Epub:
Yes Abstract:
Mammalian oocytes are arrested at G2/prophase of the first meiosis. After a hormone surge, oocytes resume meiosis, undergoing... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Bai G-Y, Choe MH, Kim J-S, Oh JS. Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes. Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322. |
Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish
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Citation:
Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127 Epub:
Not Epub Abstract:
Relapse of acute lymphoblastic leukemia (ALL) is dangerous and it worsens the prognosis of patients; however, prognostic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oh C-K, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh S-O, Heo HJ, Kim S, Kim YH. Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish. Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127. |
Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements
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Citation:
Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print] Epub:
Not Epub Abstract:
During vertebrate gastrulation, convergence & extension (C&E) of the primary anteroposterior (AP) embryonic axis is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Williams MLK, Solnica-Krezel L. Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements. Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print]. |
Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages
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Citation:
Cell Death Dis. 2020;11:277 doi:10.1038/s41419-020-2477-1 Epub:
Not Epub Abstract:
DNA damage regulated autophagy modulator 1 (DRAM1) is a stress-inducible regulator of autophagy and cell death. DRAM1 has been... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang R, Varela M, Forn-Cuní G, Torraca V, Michiel van der Vaart M, Meijer AH. Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages. Cell Death Dis. 2020;11:277 doi:10.1038/s41419-020-2477-1. |
miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis
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Citation:
Prog Neurobiol. 2020 Apr 23:101803. doi: 10.1016/j.pneurobio.2020.101803. [Epub ahead of print] Epub:
Yes Abstract:
Amyotrophic lateral sclerosis (ALS) is a relentless and fatal neurological disease characterized by the selective degeneration... Delivery Method:
intracerebroventricular (i.c.v.) injection Organism or Cell Type:
mice Citation Extract: Loffreda A, Nizzardo M, Arosio A, Ruepp MD, Calogero RA, Volinia S, Galasso M, Bendotti C, Ferrarese C, Lunetta C, Rizzuti M, Ronchi A, Mühlemann O, Tremolizzo L, Corti S, Barabino SML. miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis. Prog Neurobiol. 2020 Apr 23:101803. doi: 10.1016/j.pneurobio.2020.101803. [Epub ahead of print]. |
Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects
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Citation:
Hum Mutat. 2020 Apr 25. doi: 10.1002/humu.24028. [Epub ahead of print] Epub:
Yes Abstract:
Neural tube defects (NTDs) are severe congenital malformations caused by failed neural tube closure. Recently, autophagy is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X, Wang H. Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects. Hum Mutat. 2020 Apr 25. doi: 10.1002/humu.24028. [Epub ahead of print]. |