You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development
|
Citation:
Proc Natl Acad Sci U S A. 2020 Jun 22:201917812 [Epub ahead of print]. doi:10.1073/pnas.1917812117 Epub:
Yes Abstract:
The transcriptome of eukaryotic cells is constantly monitored for errors to avoid the production of undesired protein variants... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lawir DF, Sikora K, O'Meara CP, Schorpp M, Boehm T. Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. Proc Natl Acad Sci U S A. 2020 Jun 22:201917812 [Epub ahead of print]. doi:10.1073/pnas.1917812117. |
Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration
|
Citation:
bioRxiv;[preprint] doi:10.1101/2020.06.18.159392 Epub:
Not Epub Abstract:
Many brain pathologies are associated with liver damage, but a direct link has long remained elusive. Here, we establish a new... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang L, Jiménez JA, Earley AM, Hamlin V, Kwon V, Dixon CT, Shiau CE. Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration. bioRxiv;[preprint] doi:10.1101/2020.06.18.159392. |
Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2
|
Citation:
Proc Natl Acad Sci U S A. 2020:201922535 [Epub ahead of print] . doi: 10.1073/pnas.1922535117 Epub:
Yes Abstract:
Stemness encompasses the capability of a cell for self-renewal and differentiation. The stem cell maintains a balance between... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mushtaq M, Kovalevska L, Darekar S, Abramsson A, Zetterberg H, Kashuba V, Klein G, Arsenian-Henriksson M, Kashuba E. Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2. Proc Natl Acad Sci U S A. 2020:201922535 [Epub ahead of print] . doi: 10.1073/pnas.1922535117. |
WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways
|
Citation:
J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s10038-020-0793-z Epub:
Yes Abstract:
Neural tube defects (NTDs) are debilitating human congenital abnormalities due to failure of neural tube closure. Sonic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yin H, Peng R, Chen Z, Wang H, Zhang T, Zheng Y. WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways. J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s10038-020-0793-z. |
Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping
|
Citation:
Sci Rep. 2020;10(1):10110. doi: 10.1038/s41598-020-67077-4 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a fatal X-linked disorder caused by nonsense or frameshift mutations in the DMD gene.... Delivery Method:
Endo-Porter, local injection Organism or Cell Type:
cell culture, mice Citation Extract: Hara Y, Mizobe Y, Inoue YU, Hashimoto Y, Motohashi N, Masaki Y, Seio K, Takeda S, Nagata T, Wood MJA, Inoue T, Aoki Y. Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping. Sci Rep. 2020;10(1):10110. doi: 10.1038/s41598-020-67077-4. |
Protein Regulator of Cytokinesis 1 (PRC1) Regulates Chromosome Dynamics and Cytoplasmic Division During Mouse Oocyte Meiotic Maturation and Early Embryonic Development
|
Citation:
FEBS J. 2020 Jun 19. doi: 10.1111/febs.15458. Online ahead of print Epub:
Yes Abstract:
In contrast to the homeokinesis of mitosis, asymmetric division of cytoplasm is the conspicuous feature of meiosis in mammalian... Delivery Method:
microinjection Organism or Cell Type:
mouse zygote & 2-cell embryo Citation Extract: Zhou CJ, Wang DH, Kong XW, Han Z, Hao X, Wang XY, Wen X, Liang CG. Protein Regulator of Cytokinesis 1 (PRC1) Regulates Chromosome Dynamics and Cytoplasmic Division During Mouse Oocyte Meiotic Maturation and Early Embryonic Development. FEBS J. 2020 Jun 19. doi: 10.1111/febs.15458. Online ahead of print. |
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
|
Citation:
Cancer Cell. 2020;[Epub ahead of print] doi:10.1016/j.ccell.2020.05.010 Epub:
Yes Abstract:
Pancreatic ductal adenocarcinoma (PDAC) is driven by co-existing mutations in KRAS and TP53. However, how these mutations... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture Citation Extract: Escobar-Hoyos LF, Penson A, Kannan R, Cho H, Pan C-H, Singh RK, Apken LK, Hobbs GA, Luo R, Lecomte N, Babu S, Pan FC, Alonso-Curbelo D, Morris JP, Askan G, Grbovic-Huezo O, Ogrodowski P, Bermeo J, Saglimbeni J, Cruz CD, Ho Y-J, Lawrence SA, Melchor JP, Goda Ga, Bai K, Pastore A, Hogg SJ, Raghavan S, Bailey P, Chang DK, Biankin A, Shroyer KR, Wolpin BM, Aguirre AJ, Ventura A, Taylor B, Der CJ, Dominguez D, Kümmel D, Oeckinghaus A, Lowe SW, Bradley RK, Abdel-Wahab O, Leach SD. Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. Cancer Cell. 2020;[Epub ahead of print] doi:10.1016/j.ccell.2020.05.010. |
Tracking periocular mesenchyme derived anterior segment development using single cell transcriptomic analysis
|
Citation:
Invest Ophthalmol Vis Sci. 2020;61:3175 Epub:
Not Epub Abstract:
Purpose: The anterior segment (AS) of the eye, as well as further anterior structures, are formed by a subgroup of neural crest... Organism or Cell Type:
zebrafish Citation Extract: Voecking O, Smith J, Famulski J. Tracking periocular mesenchyme derived anterior segment development using single cell transcriptomic analysis. Invest Ophthalmol Vis Sci. 2020;61:3175. |
Optimizing oligotherapeutics for visual loss in Usher syndrome mice
|
Citation:
Invest Ophthalmol Vis Sci. 2020;Vol.61:2445 Epub:
Not Epub Abstract:
Purpose : Usher syndrome (Usher) is a syndromic form of inherited retinal dystrophy (IRD) characterized by hearing impairment... Delivery Method:
intravitreal injection Organism or Cell Type:
mice Citation Extract: Lentz JJ, Hathaway M, Robillard KN, Ponnath A, Fisher M, Rigo F, Alapure BV. Optimizing oligotherapeutics for visual loss in Usher syndrome mice. Invest Ophthalmol Vis Sci. 2020;Vol.61:2445. |
Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract
|
Citation:
Development. 2020;147:dev185900 doi:10.1242/dev.185900 Epub:
Not Epub Abstract:
Physical forces are important participants in the cellular dynamics that shape developing organs. During heart formation, for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sidhwani P, Leerberg DM, Boezio GLM, Capasso TL, Yang H, Chi NC, Roman BL, Stainier DYR, Yelon D. Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract. Development. 2020;147:dev185900 doi:10.1242/dev.185900 . |