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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Microglia phagocytose myelin sheaths to modify developmental myelination

Authors:
Hughes AN, Appel B
Citation:
Nat Neurosci. 2020;[Epub ahead of print] doi:10.1038/s41593-020-0654-2
Epub:
Yes
Abstract:
During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess...
Organism or Cell Type:
zebrafish
Citation Extract:
Hughes AN, Appel B. Microglia phagocytose myelin sheaths to modify developmental myelination. Nat Neurosci. 2020;[Epub ahead of print] doi:10.1038/s41593-020-0654-2.

Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish

Authors:
Castanon I, Hannich JT, Abrami L, Huber F, Dubois M, Müller M, van der Goot FG, Gonzalez-Gaitan M
Citation:
Nat Commun. 2020 Jul 3;11(1):3317. doi:10.1038/s41467-020-17196-3
Epub:
Not Epub
Abstract:
Oriented cell division is a fundamental mechanism to control asymmetric stem cell division, neural tube elongation and body...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Castanon I, Hannich JT, Abrami L, Huber F, Dubois M, Müller M, van der Goot FG, Gonzalez-Gaitan M. Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish. Nat Commun. 2020 Jul 3;11(1):3317. doi:10.1038/s41467-020-17196-3.

Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2

Authors:
Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen MdN, Dwivedi SKD, Ramchandran R, Mukherjee P, Bhattacharya R
Citation:
Sci Adv. 2020;6(37):eaaz8534 [Epub] doi:10.1126/sciadv.aaz8534
Epub:
Not Epub
Abstract:
The stringent expression of the hypoxia inducible factor-1α (HIF-1α) is critical to a variety of pathophysiological conditions...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen MdN, Dwivedi SKD, Ramchandran R, Mukherjee P, Bhattacharya R. Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2. Sci Adv. 2020;6(37):eaaz8534 [Epub] doi:10.1126/sciadv.aaz8534 .

Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling

Authors:
Schmid S, Willi RA, Fent K
Citation:
Aquat Toxicol. 2020 Jul 3;226:105562. doi: 10.1016/j.aquatox.2020.105562. Online ahead of print.
Epub:
Yes
Abstract:
Fish are exposed to steroids of different classes in contaminated waters, but their effects are not sufficiently understood....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schmid S, Willi RA, Fent K. Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling. Aquat Toxicol. 2020 Jul 3;226:105562. doi: 10.1016/j.aquatox.2020.105562. Online ahead of print..

CYFIP2 containing WAVE complexes inhibit cell migration

Authors:
Polesskaya A, Boutillon A, Wang Y, Lavielle M, Vacher S, Schnitzler A, Molinie N, Rocques N, Fokin A, Bièche I, David NB, Gautreau AM
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.02.184655
Epub:
Not Epub
Abstract:
Branched actin networks polymerized by the Arp2/3 complex are critical for cell migration. The WAVE complex is the major Arp2/3...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Polesskaya A, Boutillon A, Wang Y, Lavielle M, Vacher S, Schnitzler A, Molinie N, Rocques N, Fokin A, Bièche I, David NB, Gautreau AM. CYFIP2 containing WAVE complexes inhibit cell migration. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.02.184655 .

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis

Authors:
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J
Citation:
Genes Dev. 2020 Jul 2. doi: 10.1101/gad.338178.120. Online ahead of print
Epub:
Yes
Abstract:
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
explant: murine pancreatic islets
Citation Extract:
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. A role for alternative splicing in circadian control of exocytosis and glucose homeostasis. Genes Dev. 2020 Jul 2. doi: 10.1101/gad.338178.120. Online ahead of print.

Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells

Authors:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP
Citation:
J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print
Epub:
Yes
Abstract:
In vascular smooth muscle cells (VMSCs), stimulation of Ca2+ -permeable canonical transient receptor potential channel 1 (TRPC1...
Organism or Cell Type:
cell culture: contractile rat mesenteric artery vascular smooth muscle cells (VMSCs)
Citation Extract:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP. Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells. J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print.

A Novel Micropeptide Encoded by Y-Linked LINC00278 Links Cigarette Smoking and AR Signaling in Male Esophageal Squamous Cell Carcinoma

Authors:
Wu S, Zhang L, Deng J, Guo B, Li F, Wang Y, Wu R, Zhang S, Lu J, Zhou Y
Citation:
Cancer Res. 2020 Mar 13:canres.3440.2019. doi: 10.1158/0008-5472.CAN-19-3440. Online ahead of print
Epub:
Yes
Abstract:
Long non-coding RNAs (lncRNA) have been shown to play critical roles in many diseases, including esophageal squamous cell...
Organism or Cell Type:
cell culture:Het-1A, xenograft Esophageal Squamous Cell Carcinoma
Citation Extract:
Wu S, Zhang L, Deng J, Guo B, Li F, Wang Y, Wu R, Zhang S, Lu J, Zhou Y. A Novel Micropeptide Encoded by Y-Linked LINC00278 Links Cigarette Smoking and AR Signaling in Male Esophageal Squamous Cell Carcinoma. Cancer Res. 2020 Mar 13:canres.3440.2019. doi: 10.1158/0008-5472.CAN-19-3440. Online ahead of print.

Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System

Authors:
Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M
Citation:
Cancer 2020;12:1756. doi:10.3390/cancers12071756
Epub:
Not Epub
Abstract:
Primary cilium drives the left-right asymmetry process during embryonic development. Moreover, its dysregulation contributes to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M. Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System. Cancer 2020;12:1756. doi:10.3390/cancers12071756 .

Asymmetric neurogenic commitment of retinal progenitors is regulated via the Notch endocytic pathway

Authors:
Nerli E, Rocha-Martins M, Norden C
Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.06.30.179499
Epub:
Not Epub
Abstract:
During brain development, progenitor cells need to balance proliferation and differentiation in order to generate different...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nerli E, Rocha-Martins M, Norden C. Asymmetric neurogenic commitment of retinal progenitors is regulated via the Notch endocytic pathway. bioRxiv. 2020;[preprint] doi:/10.1101/2020.06.30.179499 .

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