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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis
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Citation:
PLoS Genet. 2021 Apr 5;17(4):e1009112. doi: 10.1371/journal.pgen.1009112. PMID: 33819264; PMCID: PMC8049494 Epub:
Not Epub Abstract:
We previously identified a deletion on chromosome 16p12.1 that is mostly inherited and associated with multiple... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Desai I, Karthikeyan S, Gould DJ, Yennawar S, Weiner AT, Pounraja VK, Krishnan A, Rolls MM, Lowery LA, Girirajan S. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. PLoS Genet. 2021 Apr 5;17(4):e1009112. doi: 10.1371/journal.pgen.1009112. PMID: 33819264; PMCID: PMC8049494. |
TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit
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Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print Epub:
Yes Abstract:
Sprouting angiogenesis is a highly coordinately process controlled by vascular endothelial growth factor receptor (VEGFR)-Notch... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P. TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit. FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print. |
Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a
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Citation:
Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print Epub:
Not Epub Abstract:
Diamond Blackfan Anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a. Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print. |
Transgenerational inheritance of impaired larval T cell development in zebrafish
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Citation:
Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9 Epub:
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Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Aberrant patterns of DNA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iwanami N, Lawir DF, Sikora K, O Meara C, Takeshita K, Schorpp M, Boehm T. Transgenerational inheritance of impaired larval T cell development in zebrafish. Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9. |
A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia
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Citation:
Front Cell Dev Biol. 2020;8:922. doi:10.3389/fcell.2020.571004 Epub:
Not Epub Abstract:
Background: Hemifacial microsomia (HFM) is a type of rare congenital syndrome caused by developmental disorders of the first... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yibei W, Lu P, Xiaodong L, Yushan C, Xinmiao F, Lianyan L, Yaping L, Pu W, Shuyang Z, Bo Z, Xiaowei C. A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia. Front Cell Dev Biol. 2020;8:922. doi:10.3389/fcell.2020.571004. |
Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish
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Citation:
Elife. 2020 Sep 8;9:e53761. doi: 10.7554/eLife.53761 Epub:
Not Epub Abstract:
Fibrodysplasia ossificans progressiva (FOP) is a rare human genetic disorder characterized by altered skeletal development and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Allen RS, Tajer B, Shore EM, Mullins MC. Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish. Elife. 2020 Sep 8;9:e53761. doi: 10.7554/eLife.53761. |
The single nucleotide variant at c.662A>G in human RRM2B is a loss-of-function mutation
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Citation:
Mol Genet Genomic Med. 2020 Sep 15:e1497. doi: 10.1002/mgg3.1497. Online ahead of print Epub:
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Background: Mitochondrial DNA maintenance defects (MDMDs) is one of the critical pediatric dysfunction. One of the recent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tseng YT, Li SW, HuangFu WC, Yen Y, Liu IH. The single nucleotide variant at c.662A>G in human RRM2B is a loss-of-function mutation. Mol Genet Genomic Med. 2020 Sep 15:e1497. doi: 10.1002/mgg3.1497. Online ahead of print. |
Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin
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Citation:
Int J Dev Biol. 2020 Aug 25. doi: 10.1387/ijdb.200113fz. Online ahead of print Epub:
Yes Abstract:
Photoreceptors of the vertebrate neural retina are originated from the neuroepithelium, and like other neurons, must undergo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Aparicio G, Rodao M, Badano JL, Zolessi FR. Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin. Int J Dev Biol. 2020 Aug 25. doi: 10.1387/ijdb.200113fz. Online ahead of print. |
Tek/Tie2 is not required for cardiovascular development in zebrafish
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Citation:
Development. 2020 Sep 14:dev.193029. doi: 10.1242/dev.193029. Online ahead of print Epub:
Not Epub Abstract:
Angiopoietin/TIE signalling plays a major role in blood and lymphatic vessel development. In mouse, Tek/Tie2 mutants die... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiang Z, Carlantoni C, Allanki S, Ebersberger I, Stainier DYR. Tek/Tie2 is not required for cardiovascular development in zebrafish. Development. 2020 Sep 14:dev.193029. doi: 10.1242/dev.193029. Online ahead of print. |
IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity
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Citation:
J Allergy Clin Immunol. 2020 Sep 6:S0091-6749(20)31234-3. doi: 10.1016/j.jaci.2020.08.024. Online ahead of print Epub:
Yes Abstract:
Background: ILC2s are the dominant innate lymphoid cell population in the lungs at steady state and their release of type 2... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Murine Group 2 Innate Lymphoid Cells ILC2 Citation Extract: Howard E, Lewis G, Galle-Treger L, Hurrell BP, Helou DG, Shafiei-Jahani P, Painter J, Muench GA, Soroosh P, Akbari O. IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity. J Allergy Clin Immunol. 2020 Sep 6:S0091-6749(20)31234-3. doi: 10.1016/j.jaci.2020.08.024. Online ahead of print. |