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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis
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Citation:
PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953 Epub:
Not Epub Abstract:
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953. |
Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast
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Citation:
PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414 Epub:
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The host innate immune system has developed elegant processes for the detection and clearance of invasive fungal pathogens.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scherer AK, Blair BA, Park J, Seman BG, Kelley JB, Wheeler RT. Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast. PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414. |
NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation
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Citation:
J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275 Epub:
Not Epub Abstract:
The Nck-associated protein 1–like (NCKAP1L) gene, alternatively called hematopoietic protein 1 (HEM-1), encodes a hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castro CN, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, Miao Z, Groß M, Tranchant T, Radosavljevic M, Paul N, Stemmelen T, Pitoiset F, Hirschler A, Nespola B, Molitor A, Rolli V, Pichot A, Faletti LE, Rinaldi B, Friant S, Mednikov M, Karauzum H, Aman MJ, Carapito C, Lengerke C, Ziaee V, Eyaid W, Ehl S, Alroqi F, Parvaneh N, Bahram S. NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation. J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275. |
Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.05.238139 Epub:
Not Epub Abstract:
Inducing regeneration in injured spinal cord represents one of modern medicine’s greatest challenges. Research from a variety... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hamilton AM, Borodinsky LN. Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.05.238139. |
3D quantification of zebrafish cerebrovascular architecture by automated image analysis of light sheet fluorescence microscopy datasets
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.06.239905 Epub:
Not Epub Abstract:
Zebrafish transgenic lines and light sheet fluorescence microscopy allow in-depth insights into vascular development in vivo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kugler EC, Frost J, Silva V, Plant KC, Chhabria K, Chico TJ, Armitage P. 3D quantification of zebrafish cerebrovascular architecture by automated image analysis of light sheet fluorescence microscopy datasets. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.06.239905 . |
Systematic comparison of developmental GRNs explains how novelty is incorporated in early development
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.07.231464 Epub:
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The impressive array of morphological diversity among animal taxa represents the product of millions of years of evolution.... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Cary GA, McCauley BS, Zueva O, Pattinato J, Longabaugh W, Hinman VF. Systematic comparison of developmental GRNs explains how novelty is incorporated in early development. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.07.231464 . |
Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts
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Citation:
Sci Rep. 2020 Aug 6;10(1):13254. doi:10.1038/s41598-020-69956-2 Epub:
Not Epub Abstract:
Understanding mechanisms mediating tumor metastasis is crucial for diagnostic and therapeutic targeting. Here, we take... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Asokan N, Daetwyler S, Bernas SN, Schmied C, Vogler S, Lambert K, Wobus M, Wermke M, Kempermann G, Huisken J, Brand M, Bornhäuser M. Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts. Sci Rep. 2020 Aug 6;10(1):13254. doi:10.1038/s41598-020-69956-2. |
SLC20A1 Is Involved in Urinary Tract and Urorectal Development
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Citation:
Front Cell Devel Biol. 2020;8:567. doi:10.3389/fcell.2020.00567 Epub:
Not Epub Abstract:
Previous studies in developing Xenopus and zebrafish reported that the phosphate transporter slc20a1a is expressed in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rieke JM, Zhang R, Braun D, Yilmaz Ö, Japp AS, Lopes FM, Pleschka M, Hilger AC, Schneider S, Newman WG, Beaman GM, Nordenskjöld A, Ebert A-K, Promm M, Rösch WH, Stein R, Hirsch K, Schäfer F-M, Schmiedeke E, Boemers TM, Lacher M, Kluth D, Gosemann J-H, Anderberg M, Barker G, Holmdahl G, Läckgren G, Keene D, Cervellione RM, Giorgio E, Di Grazia M, Feitz WFJ, Marcelis CLM, Van Rooij IALM, B Arend, Beckers GMA, Keegan CE, Sharma A, Dakal TC, Wittler L, Grote P, Zwink N, Jenetzky E, Brusco A, Thiele H, Ludwig M, Schweizer U, Woolf AS, Odermatt B, Reutter H. SLC20A1 Is Involved in Urinary Tract and Urorectal Development. Front Cell Devel Biol. 2020;8:567. doi:10.3389/fcell.2020.00567. |
Investigation of alpl expression and Tnap-activity in zebrafish implies conserved functions during skeletal and neuronal development
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Citation:
Sci Rep. 2020 Aug 7;10(1):13321. doi: 10.1038/s41598-020-70152-5 Epub:
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Hypophosphatasia (HPP) is a rare genetic disease with diverse symptoms and a heterogeneous severity of onset with underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ohlebusch B, Borst A, Frankenbach T, Klopocki E, Jakob F, Liedtke D, Graser S. Investigation of alpl expression and Tnap-activity in zebrafish implies conserved functions during skeletal and neuronal development. Sci Rep. 2020 Aug 7;10(1):13321. doi: 10.1038/s41598-020-70152-5. |
The Role of gfi1.2 in the Development of Zebrafish Inner Ear
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Citation:
Hearing Res. 2020 Aug 7;396:108055. doi: 10.1016/j.heares.2020.108055. Online ahead of print. Epub:
Not Epub Abstract:
Inner ear hair cells are mechanosensitive cells responsible for sensing and transmitting signals to the brain to be interpreted... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu R, Wang P, Chen X-W. The Role of gfi1.2 in the Development of Zebrafish Inner Ear. Hearing Res. 2020 Aug 7;396:108055. doi: 10.1016/j.heares.2020.108055. Online ahead of print.. |