You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes

Authors:
Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA
Citation:
Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581
Epub:
Not Epub
Abstract:
The Hippo-Yap pathway regulates multiple cellular processes in response to mechanical and other stimuli. In Drosophila, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA. Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes. Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581.

Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development

Authors:
Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.24.220475
Epub:
Not Epub
Abstract:
Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure, or spontaneous miscarriage...
Delivery Method:
Endo-Porter DMSO, microinjection
Organism or Cell Type:
cell culture: Madin-Darby Bovine Kidney (MDBK) epithelial line, Bos Taurus (cattle) embryo
Citation Extract:
Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL. Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.24.220475 .

BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis

Authors:
Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W
Citation:
Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4
Epub:
Not Epub
Abstract:
BVES is a transmembrane protein, our previous work demonstrated that single nucleotide mutations of BVES in tetralogy of fallot...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W. BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis. Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4.

Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes

Authors:
Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.21.260216
Epub:
Not Epub
Abstract:
Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN. Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.21.260216 .

Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy

Authors:
Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405
Epub:
Not Epub
Abstract:
Defects in mitophagy, the selective recycling of mitochondria through autophagy, are linked to aging, sarcopenia, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W. Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405.

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

Authors:
Veloso A, Bleuart A, Orban T, Bruyr J, Cabochette P, Germano RFV, Bernard A, Vanhollebeke B, Martin M, Dequiedt F
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.259663
Epub:
Not Epub
Abstract:
Lymphangiogenesis, the formation of lymphatic vessels is tightly linked to the development of the venous vasculature, both at...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veloso A, Bleuart A, Orban T, Bruyr J, Cabochette P, Germano RFV, Bernard A, Vanhollebeke B, Martin M, Dequiedt F. The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.259663 .

Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.

Authors:
Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH
Citation:
Military Medical Sciences. 2017;41(8):662-666 (Chinese)
Epub:
Not Epub
Abstract:
Objective: To explore and optimize the processes for synthesis of key intermediates of phosphorodiamidate morpholino...
Citation Extract:
Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH. Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.. Military Medical Sciences. 2017;41(8):662-666 (Chinese).

Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells

Authors:
Lobo S, Pereira C, Oliveira C, Almeida GM
Citation:
Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378
Epub:
Not Epub
Abstract:
De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human gastric cancer, MKN45 & GP202
Citation Extract:
Lobo S, Pereira C, Oliveira C, Almeida GM. Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells. Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378.

Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development

Authors:
Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S
Citation:
Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print
Epub:
Yes
Abstract:
Mammalian acid-labile subunit (ALS) is a serum protein that binds binary complexes between Insulin-like growth factors (IGFs)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S. Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development. Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print.

Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons

Authors:
Hahn I, Voelzmann A, Parkin J, Fuelle JB, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.19.257808
Epub:
Not Epub
Abstract:
Axons are the enormously long cable-like cellular processes of neurons that wire nervous systems and have to survive for up to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hahn I, Voelzmann A, Parkin J, Fuelle JB, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A. Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.19.257808 .

Pages