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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Collective cancer cell invasion requires RNA accumulation at the invasive front
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Citation:
Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2010872117 Epub:
Yes Abstract:
Localization of RNAs at protrusive regions of cells is important for single-cell migration on two-dimensional surfaces.... Delivery Method:
Endo-Porter or Vivo-Morpholino Organism or Cell Type:
cell culture: MDA-MB-231 Citation Extract: Chrisafis G, Wang T, Moissoglu K, Gasparski AN, Ng Y, Weigert R, Lockett SJ, Mili S. Collective cancer cell invasion requires RNA accumulation at the invasive front. Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2010872117 . |
Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation
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Citation:
JCI Insight. 2020;5(20):e133019. doi:10.1172/jci.insight.133019 Epub:
Not Epub Abstract:
Although congenital heart defects (CHDs) represent the most common birth defect, a comprehensive understanding of disease... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu P-N, Moreland T, Christian CJ, Lund TC, Steet RA, Flanagan-Steet H. Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation. JCI Insight. 2020;5(20):e133019. doi:10.1172/jci.insight.133019. |
Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom
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Citation:
Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2011120117 Epub:
Yes Abstract:
The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model for characterizing the evolution of genes... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (cniderian) Citation Extract: Sachkova MY, Landau M, Surm JM, Macrander J, Singer SA, Reitzel AM, Moran Y. Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom. Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2011120117. |
Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish
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Citation:
PLoS ONE. 2020;15(10):e0240129. doi:10.1371/journal.pone.0240129 Epub:
Not Epub Abstract:
We examined a patient and her older brother who both presented with complicated severe hypertrophic cardiomyopathy (HCM) and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Okamoto R, Goto I,Nishimura Y, Kobayashi I, Hashizume R, Yoshida Y, Ito R, Kobayashi Y, Nishikawa M, Ali Y, Saito S, Tanaka T, Sawa Y, Ito M, Dohi K. Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish. PLoS ONE. 2020;15(10):e0240129. doi:10.1371/journal.pone.0240129. |
Respiratory responses to external ammonia in zebrafish (Danio rerio)
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Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2020;[Epub] doi:10.1016/j.cbpa.2020.110822 Epub:
Yes Abstract:
The effects of high external ammonia (HEA) exposure on breathing and the potential involvement of ammonia transporting Rh... Organism or Cell Type:
zebrafish Citation Extract: Porteus C, Kumai Y, Abdallah SJ, Yew HM, Kwong RWM, Pan Y, Milsom WK, Perry SF. Respiratory responses to external ammonia in zebrafish (Danio rerio). Comp Biochem Physiol A Mol Integr Physiol. 2020;[Epub] doi:10.1016/j.cbpa.2020.110822. |
The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior
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Citation:
Science. 2020;370(6514) [Epub ahead of print] doi:10.1126/science.aba2644 Epub:
Yes Abstract:
The physical microenvironment regulates cell behavior during tissue development and homeostasis. How single cells decode... Organism or Cell Type:
zebrafish Citation Extract: Venturini V, Pezzano F, Castro FC, Häkkinen H-M, Jiménez-Delgado S, Colomer-Rosell M, Marro M, Tolosa-Ramon Q, Paz-López S, Valverde MA, Weghuber J, Loza-Alvarez P, Krieg M, Wieser S, Ruprecht V. The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior. Science. 2020;370(6514) [Epub ahead of print] doi:10.1126/science.aba2644. |
Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons
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Citation:
J Neurosci. 2020 Oct 28;40(44):8463-8477. doi: 10.1523/JNEUROSCI.2666-19.2020. Epub 2020 Oct 13. PMID: 33051346; PMCID: PMC7605418 Epub:
Yes Abstract:
Relapse to drug use can be initiated by drug-associated cues. The intensity of cue-induced drug seeking in rodent models... Delivery Method:
catheter to brain nucleus accumbans core (NAcore) Organism or Cell Type:
Rat Citation Extract: Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW
. Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons. J Neurosci. 2020 Oct 28;40(44):8463-8477. doi: 10.1523/JNEUROSCI.2666-19.2020. Epub 2020 Oct 13. PMID: 33051346; PMCID: PMC7605418. |
Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer
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Citation:
Aging. 2020;12. doi:10.18632/aging.103766 Epub:
Not Epub Abstract:
Splicing dysregulation, which leads to apoptosis resistance, has been recognized as a major hallmark for tumorigenesis and... Delivery Method:
Endo-Porter, Vivo-Morpholino Organism or Cell Type:
cell culture: gastric cancer lines MKN-28, SGC-7901, and MKN-45; xenograft mice Citation Extract: Li Y, Gao X, Wei C, Guo R, Xu H, Bai Z, Zhou J, Zhu J, Wang W, Wu Y, Li J, Zhang Z, Xie X. Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer. Aging. 2020;12. doi:10.18632/aging.103766. |
Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1
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Citation:
Sci Rep. 2020;10:17326. doi:10.1038/s41598-020-73862-y Epub:
Not Epub Abstract:
Classical cadherins are well-known adhesion molecules responsible for physically connecting neighboring cells and signaling... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1. Sci Rep. 2020;10:17326. doi:10.1038/s41598-020-73862-y. |
β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors
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Citation:
Sci Rep. 2020;10:17379. doi:10.1038/s41598-020-74360-x Epub:
Not Epub Abstract:
BNip1, which functions as a t-SNARE component of the syntaxin18 complex, is localized on the ER membrane and regulates... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nishiwaki Y, Masai I. β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors. Sci Rep. 2020;10:17379. doi:10.1038/s41598-020-74360-x. |