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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1

Authors:
Lee M, Betz C, Paatero I, Schellinx N, Yin J, Wilson CW, Ye W, Affolter M, Belting H-G
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.27.269977
Epub:
Not Epub
Abstract:
Organ morphogenesis is driven by a wealth of tightly orchestrated cellular behaviors, which ensure proper organ assembly and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee M, Betz C, Paatero I, Schellinx N, Yin J, Wilson CW, Ye W, Affolter M, Belting H-G. Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.27.269977 .

Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies

Authors:
Donati A, Schneider-Maunoury S, Vesque C
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/702282
Epub:
Not Epub
Abstract:
To produce a directional flow, ciliated epithelia display a uniform orientation of ciliary beating. Oriented beating requires...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Donati A, Schneider-Maunoury S, Vesque C. Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies. bioRxiv. 2020;[preprint] doi:10.1101/702282.

Cell-Cell Adhesion During Nephron Development Is Driven by Wnt/PCP Formin Daam1

Authors:
Krneta-Stankic V, Corkins M, Paulucci-Holthauzen A, Kloc M, Gladden A, Miller R
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.18.256123
Epub:
Not Epub
Abstract:
E-cadherin junctions facilitate the assembly and disassembly of cell-cell contacts that drive development and homeostasis of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Krneta-Stankic V, Corkins M, Paulucci-Holthauzen A, Kloc M, Gladden A, Miller R. Cell-Cell Adhesion During Nephron Development Is Driven by Wnt/PCP Formin Daam1. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.18.256123 .

Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

Authors:
Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM
Citation:
Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881
Epub:
Not Epub
Abstract:
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM. Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881.

Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis

Authors:
Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Inshya Desai, Karthikeyan S, Dagny J. Gould DJ, Yennawar S, Weiner AT, Krishnan A, Rolls M, Lowery LA, Girirajan S
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.14.295923
Epub:
Not Epub
Abstract:
We previously identified a deletion on chromosome 16p12.1 that is mostly inherited and associated with multiple...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Inshya Desai, Karthikeyan S, Dagny J. Gould DJ, Yennawar S, Weiner AT, Krishnan A, Rolls M, Lowery LA, Girirajan S. Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.14.295923 .

TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit

Authors:
Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P
Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print
Epub:
Yes
Abstract:
Sprouting angiogenesis is a highly coordinately process controlled by vascular endothelial growth factor receptor (VEGFR)-Notch...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P. TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit. FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print.

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord

Authors:
Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.258707
Epub:
Not Epub
Abstract:
Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C. Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.258707.

The N-Glycome regulates the endothelial-to-hematopoietic transition

Authors:
Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/602912
Epub:
Not Epub
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) that establish and maintain the blood system in adult vertebrates arise from...
Organism or Cell Type:
zebrafish
Citation Extract:
Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S. The N-Glycome regulates the endothelial-to-hematopoietic transition. bioRxiv. 2020;[preprint] doi:10.1101/602912 .

Glypican4 mediates Wnt transport between germ layers via signaling filopodia

Authors:
Hu B, Balaraju AK, Rodriguez JJ, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.08.288613
Epub:
Not Epub
Abstract:
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu B, Balaraju AK, Rodriguez JJ, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican4 mediates Wnt transport between germ layers via signaling filopodia. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.08.288613.

Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a

Authors:
Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM
Citation:
Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print
Epub:
Not Epub
Abstract:
Diamond Blackfan Anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a. Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print.

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