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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
The low affinity p75 neurotrophin receptor is down-regulated in congenital anomalies of the kidney and the urinary tract: Possible involvement in early nephrogenesis
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Citation:
Biochem Biophys Res Commun. 2020 Sep 25:S0006-291X(20)31831-3. doi: 10.1016/j.bbrc.2020.09.084 Epub:
Not Epub Abstract:
Congenital Anomalies of the Kidney and of the Urinary Tract (CAKUT) cover a broad range of disorders including abnormal kidney... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fédou C, Lescat O, Feuillet G, Buléon M, Neau E, Breuil B, Alvès M, Batut J, Blader P, Decramer S, Saulnier-Blache JS, Klein J, Buffin-Meyer B, Schanstra JP. The low affinity p75 neurotrophin receptor is down-regulated in congenital anomalies of the kidney and the urinary tract: Possible involvement in early nephrogenesis. Biochem Biophys Res Commun. 2020 Sep 25:S0006-291X(20)31831-3. doi: 10.1016/j.bbrc.2020.09.084. |
A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson’s Disease Arising from Parkin Mutations
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Citation:
Int J Mol Sci. 2020;21(19):7282. doi:10.3390/ijms21197282 Epub:
Not Epub Abstract:
Parkin-type autosomal recessive juvenile-onset Parkinson’s disease is caused by mutations in the PRKN gene and accounts for 50... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: PRKN patient-derived fibroblasts Citation Extract: Li D, Aung-Htut MT, Ham KA, Fletcher S, Wilton SD. A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson’s Disease Arising from Parkin Mutations. Int J Mol Sci. 2020;21(19):7282. doi:10.3390/ijms21197282. |
Beta-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism
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Citation:
Cancer Res. 2020;[Epub] doi:10.1158/0008-5472.CAN-19-3382 Epub:
Not Epub Abstract:
Disturbance of sphingolipid metabolism may represent a novel therapeutic target in metastatic melanoma, the most lethal form of... Organism or Cell Type:
zebrafish Citation Extract: Belleri M, Paganini G, Coltrini D, Ronca R, Zizioli D, Corsini M, Barbieri A, Grillo E, Calza S, Bresciani R, Maiorano E, Mastropasqua MG, Annese T, Giacomini A, Ribatti D, Casas J, Levade T, Fabrias G, Presta M. Beta-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism. Cancer Res. 2020;[Epub] doi:10.1158/0008-5472.CAN-19-3382. |
Hmx3a has essential functions in zebrafish spinal cord, ear and lateral line development
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Citation:
bioRxiv 2020.01.23.917468; doi: https://doi.org/10.1101/2020.01.23.917468 Epub:
Not Epub Abstract:
Transcription factors that contain a homeodomain DNA-binding domain have crucial functions in most aspects of cellular function... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: England SJ, Cerda GA, Kowalchuk AM, Sorice T, Grieb GM, Lewis KE. Hmx3a has essential functions in zebrafish spinal cord, ear and lateral line development. bioRxiv 2020.01.23.917468; doi: https://doi.org/10.1101/2020.01.23.917468 . |
Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.29.319731 Epub:
Not Epub Abstract:
Background: SARS-CoV-2 is the causative agent of COVID-19 and a pathogen of immense global public health importance.... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Vero-E6 and SARS-CoV-2 Citation Extract: Rosenke K, Leventhal S, Moulton H, Hatlevig S, Hawman D, Feldmann H, Stein DA. Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.29.319731. |
Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces
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Citation:
Neuroscience. 2020;[Epub ahead of print] doi:10.1016/j.neuroscience.2020.09.046 Epub:
Yes Abstract:
Growth cone - mediated axonal outgrowth and accurate synaptic targeting are central to brain morphogenesis. Translocation of... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) spinal cord explants Citation Extract: Ghate K, Mutalik SP, Sthanam LK, Sen S, Ghose A. Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces. Neuroscience. 2020;[Epub ahead of print] doi:10.1016/j.neuroscience.2020.09.046. |
VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
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Citation:
J Biol Chem. 2020;[Epub ahead of print] doi:10.1074/jbc.RA120.015282 Epub:
Yes Abstract:
The Wnt/β-catenin pathway is one of the major pathways that regulates embryonic development, adult homeostasis, and stem cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang H, Rong X, Wang C, Liu Y, Lu L, Li Y, Zhao C, Zhou J. VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs. J Biol Chem. 2020;[Epub ahead of print] doi:10.1074/jbc.RA120.015282. |
Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules
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Citation:
Sci Rep. 2020;10:15954 doi:10.1038/s41598-020-72905-8 Epub:
Not Epub Abstract:
Mutations of cilia-associated molecules cause multiple developmental defects that are collectively termed ciliopathies. However... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mallarino LE, Engel C, Ilık İA, Maticzka D, Heyl F, Müller B, Toma A. Yakulov TA, Dengjel J, Backofen R, Akhtar A, Gerd Walz G. Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules. Sci Rep. 2020;10:15954 doi:10.1038/s41598-020-72905-8. |
LRRC17 Is Linked to Prognosis of Ovarian Cancer Through a p53-dependent Anti-apoptotic Function
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Citation:
Anticancer Res. 2020;40(10):5601-9. doi:10.21873/anticanres.14573 Epub:
Not Epub Abstract:
Background/Aim: Since pathways involving LRRC17 are related to the survival of patients with various cancers, we analyzed... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oh C-K, Park JJ, Ha M, Heo HJ, Kang J, Kwon EJ, Kang JW, Kim Y, Kang JM, Yoon SZ, KO Y, Ko DS, Kim YH. LRRC17 Is Linked to Prognosis of Ovarian Cancer Through a p53-dependent Anti-apoptotic Function. Anticancer Res. 2020;40(10):5601-9. doi:10.21873/anticanres.14573. |
ndufa7 plays a critical role in cardiac hypertrophy
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Citation:
J Cell Molec Med. 2020;[Epub ahead of print] doi:10.1111/jcmm.15921 Epub:
Yes Abstract:
Cardiac hypertrophy is a common pathological change in patients with progressive cardiac function failure, which can be caused... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi X, Zhang Y, Chen R, Gong Y, Zhang M, Guan R, Rotstein OD, Liu X, Wen X-Y. ndufa7 plays a critical role in cardiac hypertrophy. J Cell Molec Med. 2020;[Epub ahead of print] doi:10.1111/jcmm.15921. |