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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes

Authors:
Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.21.260216
Epub:
Not Epub
Abstract:
Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.21.260216v1
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN. Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.21.260216 .

Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy

Authors:
Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405
Epub:
Not Epub
Abstract:
Defects in mitophagy, the selective recycling of mitochondria through autophagy, are linked to aging, sarcopenia, and...
Link:
https://www.biorxiv.org/content/10.1101/2020.03.26.010405v3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W. Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405.

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

Authors:
Veloso A, Bleuart A, Orban T, Bruyr J, Cabochette P, Germano RFV, Bernard A, Vanhollebeke B, Martin M, Dequiedt F
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.259663
Epub:
Not Epub
Abstract:
Lymphangiogenesis, the formation of lymphatic vessels is tightly linked to the development of the venous vasculature, both at...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.20.259663v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veloso A, Bleuart A, Orban T, Bruyr J, Cabochette P, Germano RFV, Bernard A, Vanhollebeke B, Martin M, Dequiedt F. The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.259663 .

Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.

Authors:
Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH
Citation:
Military Medical Sciences. 2017;41(8):662-666 (Chinese)
Epub:
Not Epub
Abstract:
Objective: To explore and optimize the processes for synthesis of key intermediates of phosphorodiamidate morpholino...
Link:
http://wprim.whocc.org.cn/admin/article/articleDetail?WPRIMID=664426&articleId=664426
Citation Extract:
Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH. Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.. Military Medical Sciences. 2017;41(8):662-666 (Chinese).

Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells

Authors:
Lobo S, Pereira C, Oliveira C, Almeida GM
Citation:
Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378
Epub:
Not Epub
Abstract:
De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may...
Link:
https://www.mdpi.com/2072-6694/12/9/2378
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human gastric cancer, MKN45 & GP202
Citation Extract:
Lobo S, Pereira C, Oliveira C, Almeida GM. Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells. Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378.

Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development

Authors:
Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S
Citation:
Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print
Epub:
Yes
Abstract:
Mammalian acid-labile subunit (ALS) is a serum protein that binds binary complexes between Insulin-like growth factors (IGFs)...
Link:
https://www.sciencedirect.com/science/article/pii/S0016648020303440
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S. Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development. Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print.

Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons

Authors:
Hahn I, Voelzmann A, Parkin J, Fuelle JB, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.19.257808
Epub:
Not Epub
Abstract:
Axons are the enormously long cable-like cellular processes of neurons that wire nervous systems and have to survive for up to...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.19.257808v2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hahn I, Voelzmann A, Parkin J, Fuelle JB, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A. Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.19.257808 .

Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein

Authors:
Li D, Adams AM, Johnsen RD, Fletcher S, Wilton SD
Citation:
Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019
Epub:
Not Epub
Abstract:
Dystrophin plays a crucial role in maintaining sarcolemma stability during muscle contractions, and mutations that prevent the...
Link:
https://www.sciencedirect.com/science/article/pii/S2162253120302481
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: murine H2K mdx myogenic cells, mice
Citation Extract:
Li D, Adams AM, Johnsen RD, Fletcher S, Wilton SD. Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein. Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019.

Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development

Authors:
Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ
Citation:
PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967
Epub:
Not Epub
Abstract:
Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008967
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ. Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967.

In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence

Authors:
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C
Citation:
Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B
Epub:
Yes
Abstract:
This study monitors dynamic progress of newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-...
Link:
https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc03090b
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C. In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence. Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B.

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