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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Transferrin receptor (TFRC) is essential for meiotic progression during mouse spermatogenesis
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Citation:
Zygote. 2020 Dec 16:1-7. doi:10.1017/S0967199420000659 Epub:
Not Epub Abstract:
Meiosis is a highly conserved process, and is responsible for the production of haploid gametes and generation of genetic... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: mouse testis explants Citation Extract: Gao T, Lin M, Wu Y, Li K, Liu C, Zhou Q, Shen C, Zheng B, Huang X. Transferrin receptor (TFRC) is essential for meiotic progression during mouse spermatogenesis. Zygote. 2020 Dec 16:1-7. doi:10.1017/S0967199420000659. |
TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production
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Citation:
Cell Immunol. 2020 Nov;357:104201. doi: 10.1016/j.cellimm.2020.104201. Epub 2020 Sep 9 Epub:
Not Epub Abstract:
The DNA binding protein AT-rich interacting domain 3a (ARID3a)2 is expressed in healthy human hematopoietic cord blood... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: human hematopoietic stem progenitor cells (HSPCs) Citation Extract: Ratliff ML, Shankar M, Guthridge JM, James JA, Webb CF. TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production. Cell Immunol. 2020 Nov;357:104201. doi: 10.1016/j.cellimm.2020.104201. Epub 2020 Sep 9. |
The tight junctions protein Claudin-5 limits endothelial cell motility
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Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.248237 Epub:
Yes Abstract:
Steinberg's differential adhesion hypothesis suggests that adhesive mechanisms are important for sorting of cells and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Stephan A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J. The tight junctions protein Claudin-5 limits endothelial cell motility. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.248237. |
The RNA helicase DDX3 induces neural crest by promoting AKT activity
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Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.184341 Epub:
Not Epub Abstract:
Mutations in the RNA helicase DDX3 have emerged as a frequent cause of intellectual disability in humans. Because many patients... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Perfetto M, Xu X, Lu C, Shi Y, Yousaf N, Li J, Yien YY, Wei S. The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development. 2020;[Epub ahead of print] doi:10.1242/dev.184341. |
16p12.1 Deletion Orthologs are Expressed in Motile Neural Crest Cells and are Important for Regulating Craniofacial Development in Xenopus laevis
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Citation:
Front Genet. 2022 Mar 24;13:833083. doi: 10.3389/fgene.2022.833083. PMID: 35401697; PMCID: PMC8987115 Epub:
Not Epub Abstract:
Copy number variants (CNVs) associated with neurodevelopmental disorders are characterized by extensive phenotypic... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lasser M, Bolduc J, Murphy L, O'Brien C, Lee S, Girirajan S, Lowery LA. 16p12.1 Deletion Orthologs are Expressed in Motile Neural Crest Cells and are Important for Regulating Craniofacial Development in Xenopus laevis. Front Genet. 2022 Mar 24;13:833083. doi: 10.3389/fgene.2022.833083. PMID: 35401697; PMCID: PMC8987115. |
Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis
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Citation:
Antioxidants 2020;9(12):1265. doi:10.3390/antiox9121265 Epub:
Not Epub Abstract:
Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and is a key antioxidant enzyme... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Ismail T, Kim Y, Chae S, Ryu H-Y, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis. Antioxidants 2020;9(12):1265. doi:10.3390/antiox9121265. |
Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation
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Citation:
Elife. 2021 May 25;10:e65390. doi: 10.7554/eLife.65390. PMID: 34032216; PMCID: PMC8205493 Epub:
Not Epub Abstract:
Morphogenesis is governed by the interplay of molecular signals and mechanical forces across multiple length scales. The last... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Huebner RJ, Malmi-Kakkada AN, Sarıkaya S, Weng S, Thirumalai D, Wallingford JB. Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation. Elife. 2021 May 25;10:e65390. doi: 10.7554/eLife.65390. PMID: 34032216; PMCID: PMC8205493. |
In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces
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Citation:
Fluids Barriers CNS. 2020;17(1):72. doi:10.1186/s12987-020-00234-z Epub:
Not Epub Abstract:
Hydrocephalus, the pathological expansion of the cerebrospinal fluid (CSF)-filled cerebral ventricles, is a common, deadly... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Dur AH, Tang T, Viviano S, Sekuri A, Willsey HR, Tagare HD, Kahle KT, Deniz E. In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces. Fluids Barriers CNS. 2020;17(1):72. doi:10.1186/s12987-020-00234-z. |
Chemical Modulators of Fibrinogen Production and Their Impact on Venous Thrombosis
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Citation:
Thromb Haemost. 2020 Dec 10. doi: 10.1055/s-0040-1718414. Online ahead of print Epub:
Yes Abstract:
Thrombosis is a leading cause of morbidity and mortality. Fibrinogen, the soluble substrate for fibrin-based clotting, has a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vilar R, Lukowski SW, Garieri M, Di Sanza C, Neerman-Arbez M, Fish RJ. Chemical Modulators of Fibrinogen Production and Their Impact on Venous Thrombosis. Thromb Haemost. 2020 Dec 10. doi: 10.1055/s-0040-1718414. Online ahead of print. |
PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
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Citation:
Sci Rep. 2020;10(1):21492. doi:10.1038/s41598-020-76338-1 Epub:
Not Epub Abstract:
Upregulation of utrophin, a dystrophin related protein, is considered a promising therapeutic approach for Duchenne muscular... Delivery Method:
injection Organism or Cell Type:
mice (mdx) Citation Extract: Sengupta K, Loro E, Khurana TS. PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD). Sci Rep. 2020;10(1):21492. doi:10.1038/s41598-020-76338-1. |