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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Abortive Intussusceptive Angiogenesis Causes Multi-Cavernous Vascular Malformations
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.14.251744 Epub:
Not Epub Abstract:
Mosaic inactivation of CCM2 in humans causes cerebral cavernous malformations (CCMs) containing adjacent dilated blood-filled... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. Abortive Intussusceptive Angiogenesis Causes Multi-Cavernous Vascular Malformations. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.14.251744. |
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production
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Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.07.015 Epub:
Yes Abstract:
Embryonic hematopoietic stem and progenitor cells (HSPCs) robustly proliferate while maintaining multilineage potential in vivo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Frame JM, Kubaczka C, Long TL, Esain V, Soto RA, Hachimi M, Jing R, Shwartz A, Goessling W, Daley GQ, North TE. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.07.015. |
De novo phosphoinositide synthesis in zebrafish is required for triad formation but not essential for myogenesis
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Citation:
PLoS ONE. 2020;15(8):e0231364. doi:10.1371/journal.pone.0231364 Epub:
Not Epub Abstract:
Phosphoinositides (PIPs) and their regulatory enzymes are key players in many cellular processes and are required for aspects... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Smith L, Fabian L, Al-Maawali A, Noche RR, Dowling JJ. De novo phosphoinositide synthesis in zebrafish is required for triad formation but not essential for myogenesis. PLoS ONE. 2020;15(8):e0231364. doi:10.1371/journal.pone.0231364. |
Pathogenic variants in IMPG1 cause autosomal dominant and autosomal recessive retinitis pigmentosa
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Citation:
J Med Genet. 2020;[Epub ahead of print] doi: 10.1136/jmedgenet-2020-107150 Epub:
Yes Abstract:
Background: Inherited retinal disorders are a clinically and genetically heterogeneous group of conditions and a major cause of... Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Olivier G, Corton M, Intartaglia D, Verbakel SK, Sergouniotis PI, Le Meur G, Dhaenens C-M, Naacke H, Avila-Fernández A, Hoyng CB, Klevering J, Bocquet B, Roubertie A, Sénéchal A, Banfi S, Muller A, Hamel CL, Black GC, Conte I, Roosing S, Zanlonghi X, Ayuso C, Meunier I, Manes G. Pathogenic variants in IMPG1 cause autosomal dominant and autosomal recessive retinitis pigmentosa. J Med Genet. 2020;[Epub ahead of print] doi: 10.1136/jmedgenet-2020-107150. |
CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos
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Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.07.013 Epub:
Not Epub Abstract:
Early embryonic development is driven exclusively by maternal gene products deposited into the oocyte. Although critical in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kushawah G, Hernandez-Huertas L, del Prado JA-N, Martinez-Morales JR, DeVore ML, Huzaifa Hassan H, Moreno-Sanchez I, Tomas-Gallardo L, Diaz-Moscoso A, Monges DE, Guelfo JR, Theune WC, Brannan EO, Wang W, Corbin TJ, Moran AM, Alvarado AS, Málaga-Trillo E, Takacs CM, Bazzini AA, Moreno-Mateos MA. CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.07.013. |
Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway
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Citation:
Sci Rep. 2020 Aug 13;10(1):13752. doi: 10.1038/s41598-020-70670-2 Epub:
Not Epub Abstract:
Sproutys are negative regulators of the Ras/Raf/MAPK signaling pathway and involved in regulation of organogenesis,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Sun J, Yoon J, Lee M, Hwang YS, Daar IO. Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway. Sci Rep. 2020 Aug 13;10(1):13752. doi: 10.1038/s41598-020-70670-2. |
The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts
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Citation:
Int J Mol Sci. 2020;21:5709. doi:10.3390/ijms21165709 Epub:
Not Epub Abstract:
The Cpi-17 (ppp1r14) gene family is an evolutionarily conserved, vertebrate specific group of protein phosphatase 1 (PP1)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lang I, Virk G, Zheng DC, Young J, Nguyen MJ, Amiri R, Fong M, Arata A, Chadaideh KS, Walsh S, Weiser DC. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Int J Mol Sci. 2020;21:5709. doi:10.3390/ijms21165709 . |
THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis
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Citation:
PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953 Epub:
Not Epub Abstract:
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. PLoS Genet. 2020;16(8):e1008953. doi:10.1371/journal.pgen.1008953. |
Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast
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Citation:
PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414 Epub:
Not Epub Abstract:
The host innate immune system has developed elegant processes for the detection and clearance of invasive fungal pathogens.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scherer AK, Blair BA, Park J, Seman BG, Kelley JB, Wheeler RT. Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast. PLoS Pathog. 2020;16(8):e1008414. doi:10.1371/journal.ppat.1008414. |
NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation
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Citation:
J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275 Epub:
Not Epub Abstract:
The Nck-associated protein 1–like (NCKAP1L) gene, alternatively called hematopoietic protein 1 (HEM-1), encodes a hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castro CN, Rosenzwajg M, Carapito R, Shahrooei M, Konantz M, Khan A, Miao Z, Groß M, Tranchant T, Radosavljevic M, Paul N, Stemmelen T, Pitoiset F, Hirschler A, Nespola B, Molitor A, Rolli V, Pichot A, Faletti LE, Rinaldi B, Friant S, Mednikov M, Karauzum H, Aman MJ, Carapito C, Lengerke C, Ziaee V, Eyaid W, Ehl S, Alroqi F, Parvaneh N, Bahram S. NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation. J Exp Med. 2020 Dec 7;217(12):e20192275. doi:10.1084/jem.20192275. |