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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS

Authors:
Tingaud-Sequeira A, Trimouille A, Marlin S, Lopez E, Berenguer M, Gherbi S, Arveiler B, Lacombe D, Rooryck C
Citation:
Mol Genet Genomic Med. 2020 Aug 1:e1375. doi: 10.1002/mgg3.1375. Online ahead of print
Epub:
Not Epub
Abstract:
Background: The Oculo-Auriculo-Vertebral Spectrum (OAVS) or Goldenhar Syndrome is an embryonic developmental disorder...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1002/mgg3.1375
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tingaud-Sequeira A, Trimouille A, Marlin S, Lopez E, Berenguer M, Gherbi S, Arveiler B, Lacombe D, Rooryck C. Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS. Mol Genet Genomic Med. 2020 Aug 1:e1375. doi: 10.1002/mgg3.1375. Online ahead of print.

Rare heterozygous GDF6 variants in patients with renal anomalies

Authors:
Martens H, Hennies I, Getwan M, Christians A, Weiss A-C, Brand F, Gjerstad AC, Christians A, Gucev Z, Geffers R, Seeman T, Kispert A, Tasic V, Bjerre A, Lienkamp SS, Haffner D, Weber RG
Citation:
Eur J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s41431-020-0678-9
Epub:
Yes
Abstract:
Although over 50 genes are known to cause renal malformation if mutated, the underlying genetic basis, most easily identified...
Link:
https://www.nature.com/articles/s41431-020-0678-9
Delivery Method:
injection into stage 39 tadpoles
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Martens H, Hennies I, Getwan M, Christians A, Weiss A-C, Brand F, Gjerstad AC, Christians A, Gucev Z, Geffers R, Seeman T, Kispert A, Tasic V, Bjerre A, Lienkamp SS, Haffner D, Weber RG. Rare heterozygous GDF6 variants in patients with renal anomalies. Eur J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s41431-020-0678-9.

New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian

Authors:
Kanska J, Frank U
Citation:
J Cell Sci. 2013 Jul 15;126(Pt 14):3192-203. doi: 10.1242/jcs.127233. Epub 2013 May 9
Epub:
Not Epub
Abstract:
Nanos is a pan-metazoan germline marker, important for germ cell development and maintenance. In flies, Nanos also acts in...
Link:
https://jcs.biologists.org/content/126/14/3192
Delivery Method:
microinjection
Organism or Cell Type:
Hydractinia echinata (cnidarian)
Citation Extract:
Kanska J, Frank U. New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian. J Cell Sci. 2013 Jul 15;126(Pt 14):3192-203. doi: 10.1242/jcs.127233. Epub 2013 May 9.

Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site

Authors:
Smith SJ, Towers N, Demetriou K, Mohun TJ
Citation:
PLoS One. 2020 Jul 29;15(7):e0235433. doi: 10.1371/journal.pone.0235433. eCollection 2020
Epub:
Not Epub
Abstract:
ADP-ribosylhydrolase-like 1 (Adprhl1) is a pseudoenzyme expressed in the developing heart myocardium of all vertebrates. In the...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235433
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Smith SJ, Towers N, Demetriou K, Mohun TJ. Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. PLoS One. 2020 Jul 29;15(7):e0235433. doi: 10.1371/journal.pone.0235433. eCollection 2020.

Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development

Authors:
Kesner P, Schohl A, Warren EC, Fan Ma F, Ruthazer ES
Citation:
Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955
Epub:
Not Epub
Abstract:
To study contributions of N-methyl-D-aspartate receptors (NMDARs) in presynaptic and postsynaptic neurons of the developing...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30936-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kesner P, Schohl A, Warren EC, Fan Ma F, Ruthazer ES. Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development. Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955.

Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis

Authors:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N
Citation:
bioRxiv 20205;[preprint] doi:10.1101/2020.07.26.221515
Epub:
Not Epub
Abstract:
Animal cytokinesis ends with the formation of a thin intercellular membrane bridge connecting the two newly formed sibling...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.26.221515v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N. Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis. bioRxiv 20205;[preprint] doi:10.1101/2020.07.26.221515.

Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1B/BUBR1 Signaling

Authors:
Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.07.24.220475
Epub:
Not Epub
Abstract:
Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure, and/or spontaneous...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.24.220475v1
Delivery Method:
microinjection
Organism or Cell Type:
Bos taurus (cattle) oocytes
Citation Extract:
Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL. Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1B/BUBR1 Signaling. bioRxiv 2020;[preprint] doi:10.1101/2020.07.24.220475 .

MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B

Authors:
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C
Citation:
EMBO J. 2020 Jul 27:e105696. doi: 10.15252/embj.2020105696. Online ahead of print
Epub:
Yes
Abstract:
Lysosomal degradation of the endoplasmic reticulum (ER) via autophagy (ER-phagy) is emerging as a critical regulator of cell...
Link:
https://www.embopress.org/doi/epdf/10.15252/embj.2020105696
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C. MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. EMBO J. 2020 Jul 27:e105696. doi: 10.15252/embj.2020105696. Online ahead of print.

Heroin Cues Reveal Astroglial Heterogeneity in the Nucleus Accumbens Core

Authors:
Kruyer A, Kalivas PW
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.22.216036
Epub:
Not Epub
Abstract:
BACKGROUND: Cues predicting heroin delivery induce heroin seeking by initiating synaptic glutamate release in the nucleus...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.22.216036v1
Delivery Method:
brain infusion
Organism or Cell Type:
Rattus norvegicus (Rat) Sprague-Dawley
Citation Extract:
Kruyer A, Kalivas PW. Heroin Cues Reveal Astroglial Heterogeneity in the Nucleus Accumbens Core. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.22.216036 .

The effect of absent blood flow on the zebrafish cerebral and trunk vasculature

Authors:
Kugler E, Snodgrass R, Bowley G, Plant K, Serbanovic-Canic J, Evans PC, Chico T, Armitage P
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.23.216192
Epub:
Not Epub
Abstract:
The role of blood flow is complex and context-dependent. In this study, we quantify the effect of the lack of blood flow on...
Link:
https://www.biorxiv.org/content/10.1101/2020.07.23.216192v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kugler E, Snodgrass R, Bowley G, Plant K, Serbanovic-Canic J, Evans PC, Chico T, Armitage P. The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.23.216192 .

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