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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development
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Citation:
Cells. 2020;9(8):2073-4409. doi:10.3390/cells9081782 Epub:
Not Epub Abstract:
Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Da’as SI, Aamer W, Hasan W, Al-Maraghi A, Al-Kurbi A, Kilani H, AlRayahi J, Zamel K, Stotland MA, Fakhro KA. PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development. Cells. 2020;9(8):2073-4409. doi:10.3390/cells9081782. |
RNA-Seq analysis on ets1 mutant embryos of Xenopus tropicalis identifies microseminoprotein beta gene 3 as an essential regulator of neural crest migration
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Citation:
FASEB J. 2020 Jul 26. doi: 10.1096/fj.202000603R. Online ahead of print Epub:
Yes Abstract:
The proto-oncogene ets1 is highly expressed in the pre-migratory and migratory neural crest (NC), and has been implicated in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis & Xenopus tropicalis Citation Extract: Wang C, Qi X, Zhou X, Sun J, Cai D, Lu G, Chen X, Jiang Z, Yao YG, Chan WY, Zhao H. RNA-Seq analysis on ets1 mutant embryos of Xenopus tropicalis identifies microseminoprotein beta gene 3 as an essential regulator of neural crest migration. FASEB J. 2020 Jul 26. doi: 10.1096/fj.202000603R. Online ahead of print. |
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
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Citation:
Life Sci Alliance. 2020;3(9):e202000786 doi:10.26508/lsa.202000786 Epub:
Not Epub Abstract:
The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute infection of the respiratory tract (COVID-19)... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Calu-3 human airway epithelial cells Citation Extract: Bestle D, Heindl MR, Limburg H, Lam van TV, Pilgram O, Moulton H, Stein DA, Hardes K, Eickmann M, Dolnik O, Rohde C, Klenk H-D, Garten W, Steinmetzer T, Böttcher-Friebertshäuser E. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells. Life Sci Alliance. 2020;3(9):e202000786 doi:10.26508/lsa.202000786. |
Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio)
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Citation:
J Exp Biol. 2020;jeb.226753 [Epub ahead of print] doi:10.1242/jeb.226753 Epub:
Yes Abstract:
Fishes living in fresh water counter the passive loss of salts by actively absorbing ions through specialized cells termed... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Parker JJ, Zimmer AM, Perry SF. Respirometry and cutaneous oxygen flux measurements reveal a negligible aerobic cost of ion regulation in larval zebrafish (Danio rerio). J Exp Biol. 2020;jeb.226753 [Epub ahead of print] doi:10.1242/jeb.226753. |
Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
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Citation:
PLoS Biol. 2020;18(7):e3000561. doi:10.1371/journal.pbio.3000561 Epub:
Not Epub Abstract:
Maternal β-catenin activity is essential and critical for dorsal induction and its dorsal activation has been thoroughly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He M, Zhang R, Jiao S, Zhang F, Ye D, Wang H, Sun Y. Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors. PLoS Biol. 2020;18(7):e3000561. doi:10.1371/journal.pbio.3000561. |
A zebrafish model of Granulin deficiency reveals essential roles in myeloid cell differentiation
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Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.07.23.217067 Epub:
Not Epub Abstract:
Granulin (GRN) is a pleiotropic protein involved in inflammation, wound healing, neurodegenerative disease, and tumorigenesis.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Palazon RE, Campbell CA, Fursova O, Cheng X, Snella E, McCune A, Li L, Solchenberger B, Schmid B, Sahoo D, Morton M, Traver D. A zebrafish model of Granulin deficiency reveals essential roles in myeloid cell differentiation. bioRxiv. 2020;[preprint] doi:/10.1101/2020.07.23.217067. |
Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy
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Citation:
Nat Commun. 2020;11(1):3698. doi:10.1038/s41467-020-17452-6 Epub:
Not Epub Abstract:
Intellectual disability (ID) is a heterogeneous clinical entity and includes an excess of males who harbor variants on the X-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee Y-R, Khan K, Armfield-Uhas K, Srikanth S, Thompson NA, Pardo M, Yu L, Norris JW, Peng Y, Gripp KW, Aleck KA, Li C, Spence E, Choi T-I, Kwon SJ, Park H-M, Yu D, Do HW, Mooney MR, Baig SM, Wentzensen IM, Telegrafi A, McWalter K, Moreland T, Roadhouse C, Ramsey K, Lyons MJ, Skinner C, Alexov E, Katsanis N, Stevenson RE, Choudhary JS, Adams DJ, Kim C-H, Davis EE, Schwartz CE. Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy. Nat Commun. 2020;11(1):3698. doi:10.1038/s41467-020-17452-6. |
The role of TASK-2 channels in CO2 sensing in zebrafish (Danio rerio)
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Citation:
Am J Physiol Regul Integr Comp Physiol. 2020 Jul 22. doi: 10.1152/ajpregu.00132.2020. Online ahead of print Epub:
Not Epub Abstract:
Peripheral chemosensitivity in fishes is thought to be mediated by serotonin-enriched neuroepithelial cells (NECs) that are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koudrina N, Perry SF, Gilmour KM. The role of TASK-2 channels in CO2 sensing in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2020 Jul 22. doi: 10.1152/ajpregu.00132.2020. Online ahead of print. |
INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.20.209130 Epub:
Not Epub Abstract:
Oral-facial-digital syndromes (OFD) are a heterogeneous group of congenital disorders characterized by malformations of the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang K-L, Peart NJ, Singh MK, Lee H, Merriman B, Jodoin JN, Lee LA, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Fathalla R, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Russell WK, Amiel J, Reversade B, Wagner EJ. INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.20.209130 . |
Automated Fast-Flow Synthesis of Antisense Phosphorodiamidate Morpholino Oligomers
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Citation:
ChemRxiv. 2020;[preprint] doi:10.26434/chemrxiv.12685886.v1 Epub:
Not Epub Abstract:
The antisense phosphorodiamidate morpholino oligomer (PMO) drugs Eteplirsen and Golodirsen are improving the lives of some... Citation Extract: Li C, Callahan AJ, Simon MD, Totaro KA, Mijalis AJ, Hartrampf N, Schissel CK, Zhou M, Zong H, Hanson GJ, Loas A, Pohl NLB, Pentelute BL. Automated Fast-Flow Synthesis of Antisense Phosphorodiamidate Morpholino Oligomers. ChemRxiv. 2020;[preprint] doi:10.26434/chemrxiv.12685886.v1. |