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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling

Authors:
Schmid S, Willi RA, Fent K
Citation:
Aquat Toxicol. 2020 Jul 3;226:105562. doi: 10.1016/j.aquatox.2020.105562. Online ahead of print.
Epub:
Yes
Abstract:
Fish are exposed to steroids of different classes in contaminated waters, but their effects are not sufficiently understood....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schmid S, Willi RA, Fent K. Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling. Aquat Toxicol. 2020 Jul 3;226:105562. doi: 10.1016/j.aquatox.2020.105562. Online ahead of print..

CYFIP2 containing WAVE complexes inhibit cell migration

Authors:
Polesskaya A, Boutillon A, Wang Y, Lavielle M, Vacher S, Schnitzler A, Molinie N, Rocques N, Fokin A, Bièche I, David NB, Gautreau AM
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.02.184655
Epub:
Not Epub
Abstract:
Branched actin networks polymerized by the Arp2/3 complex are critical for cell migration. The WAVE complex is the major Arp2/3...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Polesskaya A, Boutillon A, Wang Y, Lavielle M, Vacher S, Schnitzler A, Molinie N, Rocques N, Fokin A, Bièche I, David NB, Gautreau AM. CYFIP2 containing WAVE complexes inhibit cell migration. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.02.184655 .

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis

Authors:
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J
Citation:
Genes Dev. 2020 Jul 2. doi: 10.1101/gad.338178.120. Online ahead of print
Epub:
Yes
Abstract:
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
explant: murine pancreatic islets
Citation Extract:
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. A role for alternative splicing in circadian control of exocytosis and glucose homeostasis. Genes Dev. 2020 Jul 2. doi: 10.1101/gad.338178.120. Online ahead of print.

Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells

Authors:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP
Citation:
J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print
Epub:
Yes
Abstract:
In vascular smooth muscle cells (VMSCs), stimulation of Ca2+ -permeable canonical transient receptor potential channel 1 (TRPC1...
Organism or Cell Type:
cell culture: contractile rat mesenteric artery vascular smooth muscle cells (VMSCs)
Citation Extract:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP. Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells. J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print.

A Novel Micropeptide Encoded by Y-Linked LINC00278 Links Cigarette Smoking and AR Signaling in Male Esophageal Squamous Cell Carcinoma

Authors:
Wu S, Zhang L, Deng J, Guo B, Li F, Wang Y, Wu R, Zhang S, Lu J, Zhou Y
Citation:
Cancer Res. 2020 Mar 13:canres.3440.2019. doi: 10.1158/0008-5472.CAN-19-3440. Online ahead of print
Epub:
Yes
Abstract:
Long non-coding RNAs (lncRNA) have been shown to play critical roles in many diseases, including esophageal squamous cell...
Organism or Cell Type:
cell culture:Het-1A, xenograft Esophageal Squamous Cell Carcinoma
Citation Extract:
Wu S, Zhang L, Deng J, Guo B, Li F, Wang Y, Wu R, Zhang S, Lu J, Zhou Y. A Novel Micropeptide Encoded by Y-Linked LINC00278 Links Cigarette Smoking and AR Signaling in Male Esophageal Squamous Cell Carcinoma. Cancer Res. 2020 Mar 13:canres.3440.2019. doi: 10.1158/0008-5472.CAN-19-3440. Online ahead of print.

Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System

Authors:
Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M
Citation:
Cancer 2020;12:1756. doi:10.3390/cancers12071756
Epub:
Not Epub
Abstract:
Primary cilium drives the left-right asymmetry process during embryonic development. Moreover, its dysregulation contributes to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M. Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System. Cancer 2020;12:1756. doi:10.3390/cancers12071756 .

Asymmetric neurogenic commitment of retinal progenitors is regulated via the Notch endocytic pathway

Authors:
Nerli E, Rocha-Martins M, Norden C
Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.06.30.179499
Epub:
Not Epub
Abstract:
During brain development, progenitor cells need to balance proliferation and differentiation in order to generate different...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nerli E, Rocha-Martins M, Norden C. Asymmetric neurogenic commitment of retinal progenitors is regulated via the Notch endocytic pathway. bioRxiv. 2020;[preprint] doi:/10.1101/2020.06.30.179499 .

Disabled-2: a positive regulator of the early differentiation of myoblasts

Authors:
Shang N, Lee JTY, Huang T, Wang C, Lee TL, Mok SC, Zhao H, Chan WY
Citation:
Cell Tissue Res. 2020 Jun 30;[Epub ahead of print] doi: 10.1007/s00441-020-03237-2. Online ahead of print
Epub:
Yes
Abstract:
Dab2 is an adaptor protein and a tumor suppressor. Our previous study has found that Dab2 was expressed in early...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shang N, Lee JTY, Huang T, Wang C, Lee TL, Mok SC, Zhao H, Chan WY. Disabled-2: a positive regulator of the early differentiation of myoblasts. Cell Tissue Res. 2020 Jun 30;[Epub ahead of print] doi: 10.1007/s00441-020-03237-2. Online ahead of print.

A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation

Authors:
Ray D, Yu CY, Idris M, Cheng S, Boot A, Tan BHI, Rozen SG, Tan P, Epstein DM
Citation:
Proc Nat Acad Sci USA. 2020:202002499 [Epub ahead of print] doi:10.1073/pnas.2002499117
Epub:
Yes
Abstract:
Master splicing regulator MBNL1 shapes large transcriptomic changes that drive cellular differentiation during development....
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HFE-145
Citation Extract:
Ray D, Yu CY, Idris M, Cheng S, Boot A, Tan BHI, Rozen SG, Tan P, Epstein DM. A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation. Proc Nat Acad Sci USA. 2020:202002499 [Epub ahead of print] doi:10.1073/pnas.2002499117.

Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk

Authors:
Pined S, Nikolova-Krstevski V, Leimena C, Atkinson AJ, Altekoester A-K, Cox CD, Jacoby A, Huttner IG, Ju Y-K, Soka M, Ohanian M, Trived G, Johnson R, Molenaar P, Kuchar D, Allen DG, Hill AP, Bodmer R, Vogler G, Dobrzyn H, Ocorr K, Fatkin D
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.28.176495
Epub:
Not Epub
Abstract:
Background: KCNMA1 encodes the a-subunit of the large-conductance Ca2+-activated K+ channel, KCa1.1, and lies within a linkage...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pined S, Nikolova-Krstevski V, Leimena C, Atkinson AJ, Altekoester A-K, Cox CD, Jacoby A, Huttner IG, Ju Y-K, Soka M, Ohanian M, Trived G, Johnson R, Molenaar P, Kuchar D, Allen DG, Hill AP, Bodmer R, Vogler G, Dobrzyn H, Ocorr K, Fatkin D. Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.28.176495 .

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