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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein
Citation:
Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019 Epub:
Not Epub Abstract:
Dystrophin plays a crucial role in maintaining sarcolemma stability during muscle contractions, and mutations that prevent the... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: murine H2K mdx myogenic cells, mice Citation Extract: Li D, Adams AM, Johnsen RD, Fletcher S, Wilton SD. Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein. Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019. |
Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development
Citation:
PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967 Epub:
Not Epub Abstract:
Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ. Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967. |
In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence
Citation:
Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B Epub:
Yes Abstract:
This study monitors dynamic progress of newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C. In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence. Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B. |
The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish
Citation:
Neurosci Bull. 2020 Aug 18. doi: 10.1007/s12264-020-00554-y. Online ahead of print. Epub:
Yes Abstract:
Joubert syndrome is characterized by unique malformation of the cerebellar vermis. More than thirty Joubert syndrome genes have... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu J, Wang HT, Chen YR, Yan LY, Han YY, Liu LY, Cao Y, Liu ZZ, Xu HA. The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish. Neurosci Bull. 2020 Aug 18. doi: 10.1007/s12264-020-00554-y. Online ahead of print.. |
Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.08.17.254912 Epub:
Not Epub Abstract:
The formation of new blood vessel networks occurs via angiogenesis during development, tissue repair and disease. Angiogenesis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Okuda K, Keyser M, Gurevich DB, Sturtzel C, Paterson S, Chen H, Scott M, Condon N, Martin PB, Distel M, Hogan BM. Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis. bioRxiv 2020;[preprint] doi:10.1101/2020.08.17.254912. |
Production of common carp donor-derived offspring from goldfish surrogate broodstock
Citation:
Research Square. 2020:[preprint] doi:10.21203/rs.3.rs-57467/v1+ Epub:
Not Epub Abstract:
Background: Common carp is the fourth most-produced species in worldwide aquaculture. Significant efforts are invested in... Delivery Method:
microinjection Organism or Cell Type:
Carassius auratus (goldfish) Citation Extract: Franěk R, Kašpar V, Gela D, Pšenička M. Production of common carp donor-derived offspring from goldfish surrogate broodstock. Research Square. 2020:[preprint] doi:10.21203/rs.3.rs-57467/v1+. |
Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome
Citation:
Cell Stem Cell. 2020;[Epub ahead of print] doi:10.1016/j.stem.2020.07.015 Epub:
Not Epub Abstract:
Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease characterized by abnormalities in the left... Delivery Method:
injection Organism or Cell Type:
Xenopus Citation Extract: Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen J-R, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M. Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. Cell Stem Cell. 2020;[Epub ahead of print] doi:10.1016/j.stem.2020.07.015. |
Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation
Citation:
Cell Rep. 2020;32(7):108039. doi:10.1016/j.celrep.2020.108039 Epub:
Not Epub Abstract:
A fundamental question in developmental biology is how morphogens, such as bone morphogenetic protein (BMP), form precise... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tuazon FB, Wang X, Andrade JL, Umulis D, Mullins MC. Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation. Cell Rep. 2020;32(7):108039. doi:10.1016/j.celrep.2020.108039. |
In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.17.255158 Epub:
Not Epub Abstract:
Cerebral palsy (CP), the most prevalent physical disability in children, has long been ignored with regard to its inherent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li N, Zhou P, Tang H, He L, Fang X, Zhao J, Wang X, Qi Y, Sun C, Lin Y, Qin F, Yang M, Zhang Z, Liao C, Zheng S, Peng X, Xue T, Zhu Q, Li Y, Liu L, Huang J, Liu L, Peng C, Han D, Liu D, Xu K, Hu H(C). In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.17.255158. |
Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy
Citation:
J Am Heart Assoc. 2020 Aug 18:e017055. doi:10.1161/JAHA.119.017055. Online ahead of print Epub:
Yes Abstract:
Background Sorbs2b (sorbin and SH3 domain-containing 2b) was recently identified as a cardiomyopathy gene from a zebrafish... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ding Y, Yang J, Chen P, Lu T, Jiao K, Tester DJ, Giudicessi JR, Jiang K, Ackerman MJ, Li Y, Wang DW, Lee HC, Wang DW, Xu X. Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy. J Am Heart Assoc. 2020 Aug 18:e017055. doi:10.1161/JAHA.119.017055. Online ahead of print. |