You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
|
Citation:
Mol Ther Nucleic Acids. 2020 Jun 27;21:623-635. doi: 10.1016/j.omtn.2020.06.027. Online ahead of print Epub:
Not Epub Abstract:
Parkinson's disease (PD) is a progressive neurological disorder estimated to affect 7-10 million people worldwide. There... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: patient-derived fibroblasts Citation Extract: Korecka JA, Thomas R, Hinrich AJ, Moskites AM, Macbain ZK, Hallett PJ, Isacson O, Hastings ML. Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice. Mol Ther Nucleic Acids. 2020 Jun 27;21:623-635. doi: 10.1016/j.omtn.2020.06.027. Online ahead of print. |
Congenital sensorineural hearing loss as the initial presentation of PTPN11-associated Noonan syndrome with multiple lentigines or Noonan syndrome: clinical features and underlying mechanisms
|
Citation:
J Med Genet. 2020 Jul 31:jmedgenet-2020-106892. doi: 10.1136/jmedgenet-2020-106892. Online ahead of print Epub:
Not Epub Abstract:
Background: Germline variants in PTPN11 are the primary cause of Noonan syndrome with multiple lentigines (NSML) and Noonan... Organism or Cell Type:
zebrafish Citation Extract: Gao X, Huang SS, Qiu SW, Su Y, Wang WQ, Xu HY, Xu JC, Kang DY, Dai P, Yuan YY. Congenital sensorineural hearing loss as the initial presentation of PTPN11-associated Noonan syndrome with multiple lentigines or Noonan syndrome: clinical features and underlying mechanisms. J Med Genet. 2020 Jul 31:jmedgenet-2020-106892. doi: 10.1136/jmedgenet-2020-106892. Online ahead of print. |
Assessment of Vascular Patterning in the Zebrafish
|
Citation:
Methods Mol Biol. 2021;2206:205-222. doi: 10.1007/978-1-0716-0916-3_15 Epub:
Not Epub Abstract:
The zebrafish has emerged as a valuable and important model organism for studying vascular development and vascular biology.... Organism or Cell Type:
zebrafish Citation Extract: Stratman AN, Weinstein BM. Assessment of Vascular Patterning in the Zebrafish. Methods Mol Biol. 2021;2206:205-222. doi: 10.1007/978-1-0716-0916-3_15. |
Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS
|
Citation:
Mol Genet Genomic Med. 2020 Aug 1:e1375. doi: 10.1002/mgg3.1375. Online ahead of print Epub:
Not Epub Abstract:
Background: The Oculo-Auriculo-Vertebral Spectrum (OAVS) or Goldenhar Syndrome is an embryonic developmental disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tingaud-Sequeira A, Trimouille A, Marlin S, Lopez E, Berenguer M, Gherbi S, Arveiler B, Lacombe D, Rooryck C. Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS. Mol Genet Genomic Med. 2020 Aug 1:e1375. doi: 10.1002/mgg3.1375. Online ahead of print. |
Rare heterozygous GDF6 variants in patients with renal anomalies
|
Citation:
Eur J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s41431-020-0678-9 Epub:
Yes Abstract:
Although over 50 genes are known to cause renal malformation if mutated, the underlying genetic basis, most easily identified... Delivery Method:
injection into stage 39 tadpoles Organism or Cell Type:
Xenopus laevis Citation Extract: Martens H, Hennies I, Getwan M, Christians A, Weiss A-C, Brand F, Gjerstad AC, Christians A, Gucev Z, Geffers R, Seeman T, Kispert A, Tasic V, Bjerre A, Lienkamp SS, Haffner D, Weber RG. Rare heterozygous GDF6 variants in patients with renal anomalies. Eur J Hum Genet. 2020;[Epub ahead of print] doi:10.1038/s41431-020-0678-9. |
New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian
|
Citation:
J Cell Sci. 2013 Jul 15;126(Pt 14):3192-203. doi: 10.1242/jcs.127233. Epub 2013 May 9 Epub:
Not Epub Abstract:
Nanos is a pan-metazoan germline marker, important for germ cell development and maintenance. In flies, Nanos also acts in... Delivery Method:
microinjection Organism or Cell Type:
Hydractinia echinata (cnidarian) Citation Extract: Kanska J, Frank U. New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian. J Cell Sci. 2013 Jul 15;126(Pt 14):3192-203. doi: 10.1242/jcs.127233. Epub 2013 May 9. |
Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site
|
Citation:
PLoS One. 2020 Jul 29;15(7):e0235433. doi: 10.1371/journal.pone.0235433. eCollection 2020 Epub:
Not Epub Abstract:
ADP-ribosylhydrolase-like 1 (Adprhl1) is a pseudoenzyme expressed in the developing heart myocardium of all vertebrates. In the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Smith SJ, Towers N, Demetriou K, Mohun TJ. Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. PLoS One. 2020 Jul 29;15(7):e0235433. doi: 10.1371/journal.pone.0235433. eCollection 2020. |
Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development
|
Citation:
Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955 Epub:
Not Epub Abstract:
To study contributions of N-methyl-D-aspartate receptors (NMDARs) in presynaptic and postsynaptic neurons of the developing... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kesner P, Schohl A, Warren EC, Fan Ma F, Ruthazer ES. Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development. Cell Rep. 2020;32(4):107955. doi:10.1016/j.celrep.2020.107955. |
Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis
|
Citation:
bioRxiv 20205;[preprint] doi:10.1101/2020.07.26.221515 Epub:
Not Epub Abstract:
Animal cytokinesis ends with the formation of a thin intercellular membrane bridge connecting the two newly formed sibling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N. Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis. bioRxiv 20205;[preprint] doi:10.1101/2020.07.26.221515. |
Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1B/BUBR1 Signaling
|
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.07.24.220475 Epub:
Not Epub Abstract:
Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure, and/or spontaneous... Delivery Method:
microinjection Organism or Cell Type:
Bos taurus (cattle) oocytes Citation Extract: Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL. Genotypic Complexity in Initial Cleavage Divisions of Mammalian Embryos is Contributed by Defective BUB1B/BUBR1 Signaling. bioRxiv 2020;[preprint] doi:10.1101/2020.07.24.220475 . |