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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Amyloid-β precursor protein mutant zebrafish exhibit seizure susceptibility that depends on prion protein
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Citation:
Exp Neurol. 2020;328:113283 doi:10.1016/j.expneurol.2020.113283 Epub:
Not Epub Abstract:
It has been proposed that Amyloid β Precursor Protein (APP) might act as a rheostat controlling neuronal excitability, but... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kanyo R, Leighton PLA, Neil GJ, Locskai LF, Allison WT. Amyloid-β precursor protein mutant zebrafish exhibit seizure susceptibility that depends on prion protein. Exp Neurol. 2020;328:113283 doi:10.1016/j.expneurol.2020.113283. |
Lamprey VLRB participates in pathogen detection, VLRB/L-BLNK/L-NF-κB (B-like cells) signal transduction, and development
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Citation:
Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.05.030 Epub:
Yes Abstract:
In jawed vertebrates, B cell receptors (BCR) are primary pathogen detectors that activate downstream signaling pathways to... Delivery Method:
microinjection Organism or Cell Type:
Lampetra morii (lamprey) Citation Extract: Han Y, Li J, Pang Y, Xu L, Ma Q, Liu H, Song X, Su P, Sun F, Gou M, Lu J, Shan Y, Liu X, Li Q. Lamprey VLRB participates in pathogen detection, VLRB/L-BLNK/L-NF-κB (B-like cells) signal transduction, and development. Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.05.030. |
Acute knockdown of extracellular matrix protein Tinagl1 disrupts heart laterality and pronephric cilia in zebrafish embryonic development
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Citation:
bioRxiv. 2020;[preprint] doi: doi:10.1101/2020.06.05.136747 Epub:
Not Epub Abstract:
A highly-conserved extracellular matrix protein, Tinagl1, modulates Wnt, integrin, TGF-β, and EGF-R signaling in vitro, but its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Neiswender H, LeMosy EK. Acute knockdown of extracellular matrix protein Tinagl1 disrupts heart laterality and pronephric cilia in zebrafish embryonic development. bioRxiv. 2020;[preprint] doi: doi:10.1101/2020.06.05.136747. |
Beclin 1 controls pigmentation by changing the nuclear localization of melanogenic factor MITF
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Citation:
Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.118 Epub:
Yes Abstract:
The primary contributor for the determination of skin color is melanin, a pigment that is produced in specialized cells called... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rai A, Chatterjee B, Bhowmick S, Sagar S, Roy SS. Beclin 1 controls pigmentation by changing the nuclear localization of melanogenic factor MITF. Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.118. |
Hatching gland development and hatching in zebrafish embryos: A role for zinc and its transporters Zip10 and Znt1a
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Citation:
Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.131 Epub:
Yes Abstract:
Zinc transporters of the ZIP (Slc39, importers) and ZnT (Slc30, exporters) protein families have evolutionary conserved roles... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Muraina IA, Maret W, Bury NR, Hogstrand C. Hatching gland development and hatching in zebrafish embryos: A role for zinc and its transporters Zip10 and Znt1a. Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.131. |
Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts
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Citation:
Scars Burn. Heal. 2020;6;[Epub] doi:10.1177/2059513120908857 Epub:
Not Epub Abstract:
Background: In burn patients, wound healing is often accompanied by hypertrophic scar (HS) development, resulting in both... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: primary human fibroblasts Citation Extract: Raktoe RS, Rietveld MH, Out-Luiting JJ, Kruithof-de Julio M, van Zuijlen PPM, van Doorn R, El Ghalbzouri A. Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts. Scars Burn. Heal. 2020;6;[Epub] doi:10.1177/2059513120908857. |
Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress
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Citation:
EMBO Mol Med. 2020;e11861 [Epub] doi:10.15252/emmm.201911861 Epub:
Yes Abstract:
The ubiquitin–proteasome system degrades ubiquitin‐modified proteins to maintain protein homeostasis and to control signalling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kröll‐Hermi A, Ebstein F, Stoetzel C, Geoffroy V, Schaefer E, Scheidecker S, Bär S, Takamiya M, Kawakami K, Zieba BA, Studer F, Pelletier V, Eyermann C, Speeg‐Schatz C, Laugel V, Lipsker D, Sandron F, McGinn S, Boland A, Deleuze J-F, Kuhn L, Chicher J, Hammann P, Friant S, Etard C, Krüger E, Muller J, Strähle U, Dollfus H
. Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress. EMBO Mol Med. 2020;e11861 [Epub] doi:10.15252/emmm.201911861. |
Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals
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Citation:
Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.05.030 Epub:
Yes Abstract:
Neutrophils are major inflammatory cells that rapidly infiltrate wounds to provide antimicrobial functions. Within the damaged... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Poplimont H, Georgantzoglou A, Boulch M, Walker HA, Coombs C, Papaleonidopoulou F, Sarris M. Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals. Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.05.030. |
LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling
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Citation:
JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434 Epub:
Yes Abstract:
The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing hormone (GnRH) secretion. In turn,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L. LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling. JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434. |
Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish
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Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-27670/v1 Epub:
Not Epub Abstract:
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castellanos BS, Quintana A. Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-27670/v1. |