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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii

Authors:
Li J, Liu H, Ma Q, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Guan H, Liu X, Li Q, Han Y
Citation:
Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.07.013
Epub:
Yes
Abstract:
The complement component 3 of the lamprey, a jawless vertebrate, functions as an opsonin during the phagocytosis of rabbit red...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1050464820304976
Delivery Method:
microinjection
Organism or Cell Type:
Lampetra morii (lamprey)
Citation Extract:
Li J, Liu H, Ma Q, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Guan H, Liu X, Li Q, Han Y. VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii. Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.07.013.

Wang X, Dunlap K, Satterfield M, Frank J, Li X, Ying W, Burghardt R, Johnson GA, Wu G, Antoniazzi AQ, Nett TM, Hansen TR, Bazer FW

Authors:
Effects of In Vivo Knockdown of Translation of Arginine-Associated Gene Transcripts in Conceptus Trophectoderm on Growth, Development, and Gene Expression by Ovine Conceptuses
Citation:
Biol Reprod. 2012;87(suppl 1)394. doi:10.1093/biolreprod/87.s1.394
Epub:
Not Epub
Abstract:
Arginine (Arg), a nutritionally essential amino acid for conceptus development, can be metabolized to nitric oxide (NO) and...
Link:
https://academic.oup.com/biolreprod/article/87/Suppl_1/394/2956708
Delivery Method:
bathing in uterine lumen
Organism or Cell Type:
Ovis aries (sheep) conceptus
Citation Extract:
Effects of In Vivo Knockdown of Translation of Arginine-Associated Gene Transcripts in Conceptus Trophectoderm on Growth, Development, and Gene Expression by Ovine Conceptuses . Wang X, Dunlap K, Satterfield M, Frank J, Li X, Ying W, Burghardt R, Johnson GA, Wu G, Antoniazzi AQ, Nett TM, Hansen TR, Bazer FW. Biol Reprod. 2012;87(suppl 1)394. doi:10.1093/biolreprod/87.s1.394.

Sensory Neuroblast Quiescence Dependson Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow

Authors:
Taberner L, Banñó A, Alsina B
Citation:
Cell Rep. 2020;32:107903. doi:10.1016/j.celrep.2020.107903
Epub:
Not Epub
Abstract:
In many organs, stem cell function depends on communication with their niche partners. Cranial sensory neurons develop in...
Link:
https://www.cell.com/cell-reports/pdf/S2211-1247(20)30884-6.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taberner L, Banñó A, Alsina B. Sensory Neuroblast Quiescence Dependson Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow. Cell Rep. 2020;32:107903. doi:10.1016/j.celrep.2020.107903.

IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules

Authors:
Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A
Citation:
Nat Commun. 2020;11(1):3516 doi:10.1038/s41467-020-17091-x
Epub:
Not Epub
Abstract:
It is unclear whether the establishment of apical–basal cell polarity during the generation of epithelial lumens requires...
Link:
https://www.nature.com/articles/s41467-020-17091-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A. IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules. Nat Commun. 2020;11(1):3516 doi:10.1038/s41467-020-17091-x.

Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis

Authors:
Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried SA
Citation:
Cell Rep. 2020;32(2):107833. doi:10.1016/j.celrep.2020.107883
Epub:
Not Epub
Abstract:
The formation of cardiac valves depends on mechanical forces exerted by blood flow. Endocardial cells lining the interior of...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30864-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried SA. Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis. Cell Rep. 2020;32(2):107833. doi:10.1016/j.celrep.2020.107883.

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation

Authors:
Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, Busch-Nentwich EM, Zon LI, Illingworth RS, Patton EE
Citation:
Dev Cell. 2020 Jul 8:S1534-5807(20)30463-9. doi: 10.1016/j.devcel.2020.06.013. Online ahead of print
Epub:
Yes
Abstract:
Melanocytes, replenished throughout life by melanocyte stem cells (MSCs), play a critical role in pigmentation and melanoma....
Link:
https://www.sciencedirect.com/science/article/pii/S1534580720304639
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, Busch-Nentwich EM, Zon LI, Illingworth RS, Patton EE. PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation. Dev Cell. 2020 Jul 8:S1534-5807(20)30463-9. doi: 10.1016/j.devcel.2020.06.013. Online ahead of print.

Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia

Authors:
Gauert A, Olk N, Pimentel-Gutiérrez H, Astrahantseff K, Jensen LD, Cao Yihai, Eggert A, Eckert C, Hagemann AIH
Citation:
Cancers. 2020;12(7):[Epub] doi:10.3390/cancers12071883
Epub:
Not Epub
Abstract:
Only half of patients with relapsed B-cell precursor (BCP) acute lymphoblastic leukemia (ALL) currently survive with standard...
Link:
https://www.mdpi.com/2072-6694/12/7/1883
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gauert A, Olk N, Pimentel-Gutiérrez H, Astrahantseff K, Jensen LD, Cao Yihai, Eggert A, Eckert C, Hagemann AIH. Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia. Cancers. 2020;12(7):[Epub] doi:10.3390/cancers12071883.

Molecular basis for the distinct functions of redox-active and FeS-transfering glutaredoxins

Authors:
Trnka D, Engelke AD, Gellert M, Moseler D, Hossain MdF, Lindenberg TT, Pedroletti L, Odermatt B, de Souza JV, Bronowska AK, Dick TP, Mühlenhoff U, Meyer AJ, Berndt, Lillig CH
Citation:
Nat Commun. 2020;11:3445. doi:10.1038/s41467-020-17323-0
Epub:
Not Epub
Abstract:
Despite their very close structural similarity, CxxC/S-type (class I) glutaredoxins (Grxs) act as oxidoreductases, while CGFS-...
Link:
https://www.nature.com/articles/s41467-020-17323-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Trnka D, Engelke AD, Gellert M, Moseler D, Hossain MdF, Lindenberg TT, Pedroletti L, Odermatt B, de Souza JV, Bronowska AK, Dick TP, Mühlenhoff U, Meyer AJ, Berndt, Lillig CH. Molecular basis for the distinct functions of redox-active and FeS-transfering glutaredoxins. Nat Commun. 2020;11:3445. doi:10.1038/s41467-020-17323-0.

Cardiac Na+-Ca2+ exchanger 1 (ncx1h) is critical for the ventricular cardiomyocyte formation via regulating the expression levels of gata4 and hand2 in zebrafish

Authors:
Chu L, Yin H, Gao L, Gao L, Xia Y, Zhang C, Chen Y, Liu T, Huang J, Boheler KR, Zhou Y, Yang HT
Citation:
Sci China Life Sci. 2020 Jul 7. doi:10.1007/s11427-019-1706-1. Online ahead of print
Epub:
Yes
Abstract:
Ca2+ signaling is critical for heart development; however, the precise roles and regulatory pathways of Ca2+ transport proteins...
Link:
https://link.springer.com/article/10.1007%2Fs11427-019-1706-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chu L, Yin H, Gao L, Gao L, Xia Y, Zhang C, Chen Y, Liu T, Huang J, Boheler KR, Zhou Y, Yang HT. Cardiac Na+-Ca2+ exchanger 1 (ncx1h) is critical for the ventricular cardiomyocyte formation via regulating the expression levels of gata4 and hand2 in zebrafish. Sci China Life Sci. 2020 Jul 7. doi:10.1007/s11427-019-1706-1. Online ahead of print.

Induction of a local muscular dystrophy using electroporation in vivo: an easy tool for screening therapeutics

Authors:
Derenne A, Tassin A, Nguyen TH, De Roeck E, Jenart V, Ansseau E, Belayew A, Coppée F, Declèves A-E, Legrand A
Citation:
Sci Rep. 2020;10(1):11301. doi:10.1038/s41598-020-68135-7
Epub:
Not Epub
Abstract:
Intramuscular injection and electroporation of naked plasmid DNA (IMEP) has emerged as a potential alternative to viral vector...
Link:
https://www.nature.com/articles/s41598-020-68135-7
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Derenne A, Tassin A, Nguyen TH, De Roeck E, Jenart V, Ansseau E, Belayew A, Coppée F, Declèves A-E, Legrand A. Induction of a local muscular dystrophy using electroporation in vivo: an easy tool for screening therapeutics. Sci Rep. 2020;10(1):11301. doi:10.1038/s41598-020-68135-7.

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