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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Transgenerational inheritance of impaired larval T cell development in zebrafish
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Citation:
Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9 Epub:
Not Epub Abstract:
Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Aberrant patterns of DNA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iwanami N, Lawir DF, Sikora K, O Meara C, Takeshita K, Schorpp M, Boehm T. Transgenerational inheritance of impaired larval T cell development in zebrafish. Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9. |
A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia
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Citation:
Front Cell Dev Biol. 2020;8:922. doi:10.3389/fcell.2020.571004 Epub:
Not Epub Abstract:
Background: Hemifacial microsomia (HFM) is a type of rare congenital syndrome caused by developmental disorders of the first... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yibei W, Lu P, Xiaodong L, Yushan C, Xinmiao F, Lianyan L, Yaping L, Pu W, Shuyang Z, Bo Z, Xiaowei C. A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia. Front Cell Dev Biol. 2020;8:922. doi:10.3389/fcell.2020.571004. |
CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.08.282707 Epub:
Not Epub Abstract:
CTCF is an 11-zinc-finger DNA-binding protein that acts as a transcriptional repressor and insulator as well as an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franke M, De la Calle-Mustienes E, Neto A, Acemel RD, Tena JJ, Santos-Pereira JM, Gómez-Skarmeta JL. CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.08.282707. |
Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish
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Citation:
Elife. 2020 Sep 8;9:e53761. doi: 10.7554/eLife.53761 Epub:
Not Epub Abstract:
Fibrodysplasia ossificans progressiva (FOP) is a rare human genetic disorder characterized by altered skeletal development and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Allen RS, Tajer B, Shore EM, Mullins MC. Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish. Elife. 2020 Sep 8;9:e53761. doi: 10.7554/eLife.53761. |
The single nucleotide variant at c.662A>G in human RRM2B is a loss-of-function mutation
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Citation:
Mol Genet Genomic Med. 2020 Sep 15:e1497. doi: 10.1002/mgg3.1497. Online ahead of print Epub:
Not Epub Abstract:
Background: Mitochondrial DNA maintenance defects (MDMDs) is one of the critical pediatric dysfunction. One of the recent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tseng YT, Li SW, HuangFu WC, Yen Y, Liu IH. The single nucleotide variant at c.662A>G in human RRM2B is a loss-of-function mutation. Mol Genet Genomic Med. 2020 Sep 15:e1497. doi: 10.1002/mgg3.1497. Online ahead of print. |
Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin
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Citation:
Int J Dev Biol. 2020 Aug 25. doi: 10.1387/ijdb.200113fz. Online ahead of print Epub:
Yes Abstract:
Photoreceptors of the vertebrate neural retina are originated from the neuroepithelium, and like other neurons, must undergo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Aparicio G, Rodao M, Badano JL, Zolessi FR. Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin. Int J Dev Biol. 2020 Aug 25. doi: 10.1387/ijdb.200113fz. Online ahead of print. |
Tek/Tie2 is not required for cardiovascular development in zebrafish
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Citation:
Development. 2020 Sep 14:dev.193029. doi: 10.1242/dev.193029. Online ahead of print Epub:
Not Epub Abstract:
Angiopoietin/TIE signalling plays a major role in blood and lymphatic vessel development. In mouse, Tek/Tie2 mutants die... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiang Z, Carlantoni C, Allanki S, Ebersberger I, Stainier DYR. Tek/Tie2 is not required for cardiovascular development in zebrafish. Development. 2020 Sep 14:dev.193029. doi: 10.1242/dev.193029. Online ahead of print. |
IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity
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Citation:
J Allergy Clin Immunol. 2020 Sep 6:S0091-6749(20)31234-3. doi: 10.1016/j.jaci.2020.08.024. Online ahead of print Epub:
Yes Abstract:
Background: ILC2s are the dominant innate lymphoid cell population in the lungs at steady state and their release of type 2... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Murine Group 2 Innate Lymphoid Cells ILC2 Citation Extract: Howard E, Lewis G, Galle-Treger L, Hurrell BP, Helou DG, Shafiei-Jahani P, Painter J, Muench GA, Soroosh P, Akbari O. IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity. J Allergy Clin Immunol. 2020 Sep 6:S0091-6749(20)31234-3. doi: 10.1016/j.jaci.2020.08.024. Online ahead of print. |
NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma
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Citation:
Cell Mol Life Sci. 2020 Sep 10. doi: 10.1007/s00018-020-03632-6. Online ahead of print Epub:
Yes Abstract:
Many long non-coding RNAs (lncRNA) are highly dysregulated in cancer and are emerging as therapeutic targets. One example is... Delivery Method:
DNA leash and Lipofectamine Organism or Cell Type:
cell culture: neuroblastoma lines: KELLY, BE2C & SK-N-AS Citation Extract: Naveed A, Cooper JA, Li R, Hubbard A, Chen J, Liu T, Wilton SD, Fletcher S, Fox AH. NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma. Cell Mol Life Sci. 2020 Sep 10. doi: 10.1007/s00018-020-03632-6. Online ahead of print. |
A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish
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Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.201902308RR. Online ahead of print. Epub:
Yes Abstract:
12-Lipoxygenase (12-LOX) is a key enzyme in arachidonic acid metabolism, and alongside its major product, 12-HETE, plays a key... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hernandez-Perez M, Kulkarni A, Samala N, Sorrell C, El K, Haider I, Mukhtar Aleem A, Holman TR, Rai G, Tersey SA, Mirmira RG, Anderson RM. A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish. FASEB J. 2020 Sep 12. doi: 10.1096/fj.201902308RR. Online ahead of print.. |