You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Deletion of morpholino binding sites (DeMOBS) to assess specificity of morphant phenotypes
|
Citation:
Sci Rep. 2020 Sep 21;10(1):15366. doi: 10.1038/s41598-020-71708-1 Epub:
Not Epub Abstract:
Two complimentary approaches are widely used to study gene function in zebrafish: induction of genetic mutations, usually using... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cunningham CM, Bellipanni G, Habas R, Balciunas D. Deletion of morpholino binding sites (DeMOBS) to assess specificity of morphant phenotypes. Sci Rep. 2020 Sep 21;10(1):15366. doi: 10.1038/s41598-020-71708-1. |
Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides
|
Citation:
J Vis Exp. 2020 May 7;(159). doi: 10.3791/60672 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a degenerative muscle disease that causes progressive loss of muscle mass, leading to... Link:
Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Nordin JZ, Mizobe Y, Nakamura H, Komaki H, Takeda S, Aoki Y. Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides. J Vis Exp. 2020 May 7;(159). doi: 10.3791/60672. |
Autophagy induction promotes renal cyst growth in polycystic kidney disease
|
Citation:
EBioMedicine. 2020 Sep 16;60:102986. doi: 10.1016/j.ebiom.2020.102986. Online ahead of print Epub:
Yes Abstract:
Background: Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee EJ, Ko JY, Oh S, Jun J, Mun H, Lim CJ, Seo S, Ko HW, Kim H, Oh YK, Ahn C, Kang M, Kim MJ, Yoo KH, Oh GT, Park JH. Autophagy induction promotes renal cyst growth in polycystic kidney disease. EBioMedicine. 2020 Sep 16;60:102986. doi: 10.1016/j.ebiom.2020.102986. Online ahead of print. |
Posttranscriptional regulation of maternal Pou5f1/Oct4 during mouse oogenesis and early embryogenesis
|
Citation:
Histochem Cell Biol. 2020 Sep 15. doi: 10.1007/s00418-020-01915-4. Online ahead of print. PMID: 32930837 Epub:
Yes Abstract:
Protein syntheses at appropriate timings are important for promoting diverse biological processes and are controlled at the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Takada Y, Iyyappan R, Susor A, Kotani T. Posttranscriptional regulation of maternal Pou5f1/Oct4 during mouse oogenesis and early embryogenesis. Histochem Cell Biol. 2020 Sep 15. doi: 10.1007/s00418-020-01915-4. Online ahead of print. PMID: 32930837 . |
Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans
|
Citation:
Redox Biol. 2020;101723. doi:10.1016/j.redox.2020.101723 Epub:
Not Epub Abstract:
Increased methylglyoxal (MG) formation is associated with diabetes and its complications. In zebrafish, knockout of the main MG... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lou B, Boger M, Bennewitz K, Sticht C, Kopf S, Morgenstern J, Fleming T, Hell R, Yuan Z, Nawroth PP, Kroll J. Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans. Redox Biol. 2020;101723. doi:10.1016/j.redox.2020.101723. |
Knockdown of Gene Expression Following Activation of the NMD Pathway Using Splice-Switching Oligonucleotides
|
Citation:
Methods Mol Biol. 2025;2962:237-253. doi: 10.1007/978-1-0716-4726-4_16. PMID: 40699433 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) are commonly used to induce transient changes in gene expression and do not result in... Delivery Method:
Vivo-Morpholino versus "transfection" of standard Morpholinos Organism or Cell Type:
cell culture: SUDHL4 and OCILY10 (DLBCL) lines, primary Human Peripheral Blood Mononuclear B Cells (PBMC) Citation Extract: Hirt P, Marchalot A, Horiot C, Moreaux J, Delpy L. Knockdown of Gene Expression Following Activation of the NMD Pathway Using Splice-Switching Oligonucleotides. Methods Mol Biol. 2025;2962:237-253. doi: 10.1007/978-1-0716-4726-4_16. PMID: 40699433. |
Molluskan Dorsal-Ventral Patterning Relying on BMP2/4 and Chordin Provides Insights into Spiralian Development and Evolution
|
Citation:
Mol Biol Evol. 2022 Jan 7;39(1):msab322. doi: 10.1093/molbev/msab322. PMID: 34751376; PMCID: PMC8789067 Epub:
Not Epub Abstract:
Although a conserved mechanism relying on BMP2/4 and Chordin is suggested for animal dorsal-ventral (DV) patterning, this... Delivery Method:
microinjection Organism or Cell Type:
Lottia goshimai (limpet) Citation Extract: Tan S, Huan P, Liu B. Molluskan Dorsal-Ventral Patterning Relying on BMP2/4 and Chordin Provides Insights into Spiralian Development and Evolution. Mol Biol Evol. 2022 Jan 7;39(1):msab322. doi: 10.1093/molbev/msab322. PMID: 34751376; PMCID: PMC8789067. |
Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1
|
Citation:
Development. 2021 Aug 1;148(15):dev197509. doi: 10.1242/dev.197509. Epub 2021 Aug 12. PMID: 34383884; PMCID: PMC8380458 Epub:
Not Epub Abstract:
Organ morphogenesis is driven by a wealth of tightly orchestrated cellular behaviors, which ensure proper organ assembly and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee M, Betz C, Yin J, Paatero I, Schellinx N, Carte AN, Wilson CW, Ye W, Affolter M, Belting HG. Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1. Development. 2021 Aug 1;148(15):dev197509. doi: 10.1242/dev.197509. Epub 2021 Aug 12. PMID: 34383884; PMCID: PMC8380458. |
The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development
|
Citation:
Cell Rep. 2021 Jul 6;36(1):109340. doi: 10.1016/j.celrep.2021.109340. PMID: 34233186; PMCID: PMC8629027 Epub:
Not Epub Abstract:
E-cadherin junctions facilitate assembly and disassembly of cell contacts that drive development and homeostasis of epithelial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Krneta-Stankic V, Corkins ME, Paulucci-Holthauzen A, Kloc M, Gladden AB, Miller RK. The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development. Cell Rep. 2021 Jul 6;36(1):109340. doi: 10.1016/j.celrep.2021.109340. PMID: 34233186; PMCID: PMC8629027. |
Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk
|
Citation:
Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881 Epub:
Not Epub Abstract:
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM. Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881. |