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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma
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Citation:
Cell Mol Life Sci. 2020 Sep 10. doi: 10.1007/s00018-020-03632-6. Online ahead of print Epub:
Yes Abstract:
Many long non-coding RNAs (lncRNA) are highly dysregulated in cancer and are emerging as therapeutic targets. One example is... Delivery Method:
DNA leash and Lipofectamine Organism or Cell Type:
cell culture: neuroblastoma lines: KELLY, BE2C & SK-N-AS Citation Extract: Naveed A, Cooper JA, Li R, Hubbard A, Chen J, Liu T, Wilton SD, Fletcher S, Fox AH. NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma. Cell Mol Life Sci. 2020 Sep 10. doi: 10.1007/s00018-020-03632-6. Online ahead of print. |
A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish
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Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.201902308RR. Online ahead of print. Epub:
Yes Abstract:
12-Lipoxygenase (12-LOX) is a key enzyme in arachidonic acid metabolism, and alongside its major product, 12-HETE, plays a key... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hernandez-Perez M, Kulkarni A, Samala N, Sorrell C, El K, Haider I, Mukhtar Aleem A, Holman TR, Rai G, Tersey SA, Mirmira RG, Anderson RM. A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish. FASEB J. 2020 Sep 12. doi: 10.1096/fj.201902308RR. Online ahead of print.. |
Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders
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Citation:
Genesis. 2020 Sep 11:e23394. doi: 10.1002/dvg.23394. Online ahead of print Epub:
Yes Abstract:
The chromodomain family member chromodomain 1 (CHD1) has been shown to have numerous critical molecular functions including... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wyatt BH, Raymond TO, Lansdon LA, Darbro BW, Murray JC, Manak JR, Dickinson AJG. Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders. Genesis. 2020 Sep 11:e23394. doi: 10.1002/dvg.23394. Online ahead of print. |
Esco2 and Cohesin Regulate CRL4 Ubiquitin Ligase ddb1 Expression and Thalidomide Teratogenicity
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.02.280149 Epub:
Not Epub Abstract:
Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanchez AC, Thren ED, Iovine MK, Skibbens RV. Esco2 and Cohesin Regulate CRL4 Ubiquitin Ligase ddb1 Expression and Thalidomide Teratogenicity. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.02.280149. |
Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation
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Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.09.03.281659 Epub:
Not Epub Abstract:
The dynamic control of the actin cytoskeleton is a key aspect of essentially all animal cell movements. Experiments in single... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Devitt CC, Lee C, Cox RM, Papoulas O, Alvarado J, Marcotte EM, Wallingford JB. Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation. bioRxiv. 2020;[preprint] doi:/10.1101/2020.09.03.281659. |
A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs
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Citation:
Nature. 2007 Apr 26;446(7139):1100-4. doi: 10.1038/nature05688. Epub 2007 Apr 4 Epub:
Not Epub Abstract:
In vertebrates, unfertilized eggs (or mature oocytes) are arrested at metaphase of meiosis II by a cytoplasmic activity called... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Inoue D, Ohe M, Kanemori Y, Nobui T, Sagata N. A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs. Nature. 2007 Apr 26;446(7139):1100-4. doi: 10.1038/nature05688. Epub 2007 Apr 4. |
Critical Role for Cold Shock Protein YB-1 in Cytokinesis
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Citation:
Cancers (Basel). 2020 Sep 1;12(9):E2473. doi: 10.3390/cancers12092473 Epub:
Not Epub Abstract:
High levels of the cold shock protein Y-box-binding protein-1, YB-1, are tightly correlated with increased cell proliferation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mehta S, Algie M, Al-Jabry T, McKinney C, Kannan S, Verma CS, Ma W, Zhang J, Bartolec TK, Masamsetti VP, Parker K, Henderson L, Gould ML, Bhatia P, Harfoot R, Chircop M, Kleffmann T, Cohen SB, Woolley AG, Cesare AJ, Braithwaite A. Critical Role for Cold Shock Protein YB-1 in Cytokinesis. Cancers (Basel). 2020 Sep 1;12(9):E2473. doi: 10.3390/cancers12092473. |
Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish
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Citation:
Nat Cell Biol. 2020 Sep;22(9):1049-1055. doi: 10.1038/s41556-020-0564-2. Epub 2020 Aug 31 Epub:
Not Epub Abstract:
Rapid wound detection by distant leukocytes is essential for antimicrobial defence and post-infection survival1. The reactive... Organism or Cell Type:
zebrafish Citation Extract: Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, Niethammer P. Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish. Nat Cell Biol. 2020 Sep;22(9):1049-1055. doi: 10.1038/s41556-020-0564-2. Epub 2020 Aug 31. |
Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway
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Citation:
Development. 2020 Aug 28:dev.188094. doi: 10.1242/dev.188094. Online ahead of print Epub:
Yes Abstract:
Among the three embryonic germ layers, the mesoderm plays a central role in the establishment of the vertebrate body plan. The... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY. Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway. Development. 2020 Aug 28:dev.188094. doi: 10.1242/dev.188094. Online ahead of print. |
Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease
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Citation:
Genome Med. 2020 Aug 28;12(1):76. doi: 10.1186/s13073-020-00772-z Epub:
Not Epub Abstract:
Background: Congenital heart disease (CHD) occurs in almost 1% of newborn children and is considered a multifactorial disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Izarzugaza JMG, Ellesøe SG, Doganli C, Ehlers NS, Dalgaard MD, Audain E, Dombrowsky G, Banasik K, Sifrim A, Wilsdon A, Thienpont B, Breckpot J, Gewillig M; Competence Network for Congenital Heart Defects, Germany, Brook JD, Hitz MP, Larsen LA, Brunak S. Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease. Genome Med. 2020 Aug 28;12(1):76. doi: 10.1186/s13073-020-00772-z. |