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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish
Citation:
Res Pract Thromb Haemost. 2020 Sep 22;4(7):1150-1157. doi: 10.1002/rth2.12428. eCollection 2020 Oct Epub:
Not Epub Abstract:
Background: Blood clotting in humans is initiated by the binding of tissue factor to activated coagulation factor VII (FVIIa)... Delivery Method:
Vivo-Morpholino (piggyback) Organism or Cell Type:
zebrafish Citation Extract: Khandekar G, Iyer N, Jagadeeswaran P. Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish. Res Pract Thromb Haemost. 2020 Sep 22;4(7):1150-1157. doi: 10.1002/rth2.12428. eCollection 2020 Oct. |
Influence of astrocytic glutamine transporter SN1 deficiency on electrophysiological correlates of glutamatergic transmission
Citation:
J Neurochem. 2017; 142(suppl 1):125. doi:10.1111/jnc.14093 Epub:
Not Epub Abstract:
The N-system glutamine transporter SN1 preferentially transfers glutamine out of astrocytes (Chaudhry et al., Cell 1999), and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Popek M, Bobula B, Sowa J, Hess G, Albrecht J, Zielinska M. Influence of astrocytic glutamine transporter SN1 deficiency on electrophysiological correlates of glutamatergic transmission. J Neurochem. 2017; 142(suppl 1):125. doi:10.1111/jnc.14093. |
Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation
Citation:
J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2020.07.008 Epub:
Yes Abstract:
Congenital hearing loss is a common disorder worldwide. Heterogeneous gene variation accounts for approximately 20% - 25% of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Su X, Feng Y, Rahman SA, Wu S, Li G, Rüschendorf F, Zhao L, Cui H, Liang J, Fang L, Hu H, Froehler S, Yu Y, Patone G, Hummel O, Chen Q, Raile K, Luft FC, Bähring S, Hussain K, Chen W, Zhang J, Gong. Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation. J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2020.07.008. |
Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis
Citation:
Stem Cells. 2020 Oct 27. doi: 10.1002/stem.3287. Online ahead of print Epub:
Yes Abstract:
In the peripheral nervous system (PNS), proper development of Schwann cells (SCs) contributing to axonal myelination is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Won SY, Kwon S, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE. Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis. Stem Cells. 2020 Oct 27. doi: 10.1002/stem.3287. Online ahead of print. |
Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition
Citation:
Cell Rep. 2020;33(4):108311. doi:10.1016/j.celrep.2020.108311 Epub:
Not Epub Abstract:
Animal embryogenesis requires a precise coordination between morphogenesis and cell fate specification. During mesoderm... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kinney BA, Anber AA, Row RH, Tseng Y-J, Weidmann MD, Knaut H, Martin BL. Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition. Cell Rep. 2020;33(4):108311. doi:10.1016/j.celrep.2020.108311. |
GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons
Citation:
FASEB J. 2020 Oct 27;[Epub ahead of print] doi:10.1096/fj.202001113R. Online ahead of print Epub:
Yes Abstract:
Developmental and epileptic encephalopathy (DEE) represents a group of neurodevelopmental disorders characterized by infantile‐... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Akamine S, Okuzono S, Yamamoto H, Setoyama D, Sagata N, Ohgidani M, Kato TA, Ishitani T, Kato H, Masuda K, Matsushita Y, Ono H, Ishizaki Y, Sanefuji M, Saitsu H, Matsumoto N, Kang D, Kanba S, Nakabeppu Y, Sakai Y, Ohga S. GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons. FASEB J. 2020 Oct 27;[Epub ahead of print] doi:10.1096/fj.202001113R. Online ahead of print. |
Actin-based protrusions lead microtubules during stereotyped axon initiation in spinal neurons in vivo
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.24.353284 Epub:
Not Epub Abstract:
In vitro, developing neurons progress through well-defined stages to form an axon and multiple dendrites. In vivo, neurons are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moore RE, Pop S, Alleyne C, Clarke JDW. Actin-based protrusions lead microtubules during stereotyped axon initiation in spinal neurons in vivo. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.24.353284 . |
Dual function of perivascular fibroblasts in vascular stabilization in zebrafish
Citation:
PLoS Genet. 2020;16(10):e1008800. doi:10.1371/journal.pgen.1008800 Epub:
Not Epub Abstract:
Blood vessels are vital to sustain life in all vertebrates. While it is known that mural cells (pericytes and smooth muscle... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rajan AM, Ma RC, Kocha KM, Zhang DJ, Huang P. Dual function of perivascular fibroblasts in vascular stabilization in zebrafish. PLoS Genet. 2020;16(10):e1008800. doi:10.1371/journal.pgen.1008800. |
Dopachrome tautomerase variants in patients with oculocutaneous albinism
Citation:
Genet Med. 2020 Oct 26. doi: 10.1038/s41436-020-00997-8. Online ahead of print Epub:
Yes Abstract:
Purpose: Albinism is a clinically and genetically heterogeneous condition. Despite analysis of the 20 known genes, ~30%... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B. Dopachrome tautomerase variants in patients with oculocutaneous albinism. Genet Med. 2020 Oct 26. doi: 10.1038/s41436-020-00997-8. Online ahead of print. |
E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow
Citation:
Nat Commun. 2020 Oct 26;11(1):5397. doi: 10.1038/s41467-020-19114-z Epub:
Not Epub Abstract:
The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Grimaldi C, Schumacher I, Boquet-Pujadas A, Tarbashevich K, Vos BE, Bandemer J, Schick J, Aalto A, Olivo-Marin JC, Betz T, Raz E. E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow. Nat Commun. 2020 Oct 26;11(1):5397. doi: 10.1038/s41467-020-19114-z. |