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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning
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Citation:
Nat Methods. 2021. doi:10.1038/s41592-021-01058-x Epub:
Not Epub Abstract:
Light-field microscopy has emerged as a technique of choice for high-speed volumetric imaging of fast biological processes.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P. Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning. Nat Methods. 2021. doi:10.1038/s41592-021-01058-x. |
Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish
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Citation:
Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409 Epub:
Not Epub Abstract:
Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid... Delivery Method:
injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Sengupta A, Padhan DK, Ganguly A, Sen M. Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish. Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409. |
Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation
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Citation:
Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w Epub:
Not Epub Abstract:
Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: PC12 Citation Extract: Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fernández-Rodriguez J, Blanco I, Castellanos E, Carrió M, Lazaro C, Serra E. Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation. Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w. |
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides
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Citation:
Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease caused by frameshift or nonsense mutations in the DMD gene... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture:CXMDJ immortalized myoblasts Citation Extract: Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y. Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides. Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print. |
Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation
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Citation:
Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693 Epub:
Not Epub Abstract:
Integrated molecular signals regulate cell fate decisions in the embryonic aortic endothelium to drive hematopoietic stem cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E. Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation. Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693. |
The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development
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Citation:
Neural Dev. 2017 Feb 15;12(1):3. doi: 10.1186/s13064-017-0080-7. PMID: 28202041; PMCID: PMC5312526 Epub:
Not Epub Abstract:
Background: Formation of precise neuronal connections requires proper axon guidance. Microtubules (MTs) of the growth cone... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Erdogan B, Cammarata GM, Lee EJ, Pratt BC, Francl AF, Rutherford EL, Lowery LA. The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development. Neural Dev. 2017 Feb 15;12(1):3. doi: 10.1186/s13064-017-0080-7. PMID: 28202041; PMCID: PMC5312526. |
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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Citation:
eLife. 2021;10:e59067 doi:10.7554/eLife.59067 Epub:
Not Epub Abstract:
Genetic variants associated with type 2 diabetes (T2D) risk affect gene regulation in metabolically relevant tissues, such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. eLife. 2021;10:e59067 doi:10.7554/eLife.59067. |
l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain
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Citation:
Front Genet. 2021 Jan 21;11:612343. doi: 10.3389/fgene.2020.612343. eCollection 2020 Epub:
Not Epub Abstract:
Isomerization of l-aspartyl and l-asparaginyl residues to l-isoaspartyl residues is one type of protein damage that can occur... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Soliman R, Cordero-Maldonado ML, Martins TG, Moein M, Conrotte JF, Warmack RA, Skupin A, Crawford AD, Clarke SG, Linster CL. l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain. Front Genet. 2021 Jan 21;11:612343. doi: 10.3389/fgene.2020.612343. eCollection 2020. |
Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine
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Citation:
Nat Commun. 2021 Feb 5;12(1):833. doi: 10.1038/s41467-021-21053-2 Epub:
Not Epub Abstract:
The structure of proline prevents it from adopting an optimal position for rapid protein synthesis. Poly-proline-tract (PPT)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faundes V, Jennings MD, Crilly S, Legraie S, Withers SE, Cuvertino S, Davies SJ, Douglas AGL, Fry AE, Harrison V, Amiel J, Lehalle D, Newman WG, Newkirk P, Ranells J, Splitt M, Cross LA, Saunders CJ, Sullivan BR, Granadillo JL, Gordon CT, Kasher PR, Pavitt GD, Banka S. Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine. Nat Commun. 2021 Feb 5;12(1):833. doi: 10.1038/s41467-021-21053-2. |
Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk
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Citation:
Development. 2021 Feb 5:dev.194993. doi: 10.1242/dev.194993. Online ahead of print Epub:
Not Epub Abstract:
Previous studies have shown that Vasohibin-1 (Vash1) is stimulated by VEGFs in endothelial cells and that its overexpression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bastos de Oliveira M, Meier K, Jung S, Bartels-Klein E, Coxam B, Geudens I, Szymborska A, Skoczylas R, Fechner I, Koltowska K, Gerhardt H. Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk. Development. 2021 Feb 5:dev.194993. doi: 10.1242/dev.194993. Online ahead of print. |