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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

DNA Methylation Reprogramming during Sex Determination and Transition in Zebrafish

Authors:
Wang X, Ma X, Wei G, Ma W, Zhang Z, Chen X, Gao L, Liu Z, Yuan Y, Yi L, Wang J, Tokumoto T, Huang J, Chen D, Zhang J, Liu J
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.17.301580
Epub:
Not Epub
Abstract:
It is a mystery about sex determination and sexual plasticity in species without sex chromosomes. DNA methylation is a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Ma X, Wei G, Ma W, Zhang Z, Chen X, Gao L, Liu Z, Yuan Y, Yi L, Wang J, Tokumoto T, Huang J, Chen D, Zhang J, Liu J. DNA Methylation Reprogramming during Sex Determination and Transition in Zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.17.301580 .

Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles

Authors:
Didiano D, Abner JJ, Hinger SA, Flickinger Z, Kent M, Clement MA, Balaiya S, Liu Q, Dai X, Levine EM, Patton JG
Citation:
Exp Eye Res. 2020 Sep 19:108254. doi: 10.1016/j.exer.2020.108254. Online ahead of print
Epub:
Not Epub
Abstract:
Ongoing research using cell transplantation and viral-mediated gene therapy has been making progress to restore vision by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Didiano D, Abner JJ, Hinger SA, Flickinger Z, Kent M, Clement MA, Balaiya S, Liu Q, Dai X, Levine EM, Patton JG. Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles. Exp Eye Res. 2020 Sep 19:108254. doi: 10.1016/j.exer.2020.108254. Online ahead of print.

Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis

Authors:
Pentagna N, Pinheiro da Costa T, Soares Dos Santos Cardoso F, Martins de Almeida F, Blanco Martinez AM, Abreu JG, Levin M, Carneiro K
Citation:
Dev Comp Immunol. 2020 Aug 25;114:103840. doi: 10.1016/j.dci.2020.103840. Online ahead of print
Epub:
Not Epub
Abstract:
In the present work we have focused on the Histone Deacetylase (HDAC) control of myeloid cells behavior during Xenopus tail...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pentagna N, Pinheiro da Costa T, Soares Dos Santos Cardoso F, Martins de Almeida F, Blanco Martinez AM, Abreu JG, Levin M, Carneiro K. Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis. Dev Comp Immunol. 2020 Aug 25;114:103840. doi: 10.1016/j.dci.2020.103840. Online ahead of print.

RNA localization and co-translational interactions control RAB13 GTPase function and cell migration

Authors:
Moissoglu K, Stueland M, Gasparski AN, Wang T, Jenkins LM, Hastings ML, Mili S
Citation:
EMBO J. 2020 Sep 18:e2020104958. doi: 10.15252/embj.2020104958. Online ahead of print
Epub:
Not Epub
Abstract:
Numerous RNAs exhibit specific distribution patterns in mammalian cells. However, the functional and mechanistic consequences...
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
cell culture: NIH/3T3 mouse fibroblast, MDA‐MB‐231 human breast cancer
Citation Extract:
Moissoglu K, Stueland M, Gasparski AN, Wang T, Jenkins LM, Hastings ML, Mili S. RNA localization and co-translational interactions control RAB13 GTPase function and cell migration. EMBO J. 2020 Sep 18:e2020104958. doi: 10.15252/embj.2020104958. Online ahead of print.

Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation

Authors:
Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.18.303230
Epub:
Not Epub
Abstract:
Integrated molecular signals regulate cell fate during embryonic hematopoietic stem cell (HSC) generation. The G-protein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E. Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.18.303230.

Using the Zebrafish Model to Study T Cell Development

Authors:
Zhang Y, Wiest DL
Citation:
Methods Mol Biol. 2016;1323:273-92. doi: 10.1007/978-1-4939-2809-5_22
Epub:
Not Epub
Abstract:
While zebrafish has for some time been regarded as a powerful model organism with which to study early events in hematopoiesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Wiest DL. Using the Zebrafish Model to Study T Cell Development. Methods Mol Biol. 2016;1323:273-92. doi: 10.1007/978-1-4939-2809-5_22.

Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state

Authors:
Helker CS, Eberlein J, Wilhelm K, Sugino T, Malchow J, Schuermann A, Baumeister S, Kwon HB, Maischein HM, Potente M, Herzog W, Stainier DY
Citation:
Elife. 2020 Sep 21;9:e55589. doi: 10.7554/eLife.55589. Online ahead of print
Epub:
Not Epub
Abstract:
To form new blood vessels (angiogenesis), endothelial cells (ECs) must be activated and acquire highly migratory and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Helker CS, Eberlein J, Wilhelm K, Sugino T, Malchow J, Schuermann A, Baumeister S, Kwon HB, Maischein HM, Potente M, Herzog W, Stainier DY. Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state. Elife. 2020 Sep 21;9:e55589. doi: 10.7554/eLife.55589. Online ahead of print.

Deletion of morpholino binding sites (DeMOBS) to assess specificity of morphant phenotypes

Authors:
Cunningham CM, Bellipanni G, Habas R, Balciunas D
Citation:
Sci Rep. 2020 Sep 21;10(1):15366. doi: 10.1038/s41598-020-71708-1
Epub:
Not Epub
Abstract:
Two complimentary approaches are widely used to study gene function in zebrafish: induction of genetic mutations, usually using...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cunningham CM, Bellipanni G, Habas R, Balciunas D. Deletion of morpholino binding sites (DeMOBS) to assess specificity of morphant phenotypes. Sci Rep. 2020 Sep 21;10(1):15366. doi: 10.1038/s41598-020-71708-1.

Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides

Authors:
Nordin JZ, Mizobe Y, Nakamura H, Komaki H, Takeda S, Aoki Y
Citation:
J Vis Exp. 2020 May 7;(159). doi: 10.3791/60672
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a degenerative muscle disease that causes progressive loss of muscle mass, leading to...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Nordin JZ, Mizobe Y, Nakamura H, Komaki H, Takeda S, Aoki Y. Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides. J Vis Exp. 2020 May 7;(159). doi: 10.3791/60672.

Mouse fertilization triggers a conserved transcription program in one-cell embryos

Authors:
Asami M, Lam BYH, Hoffmann M, Suzuki T, Lu X, VerMilyea MD, Yoshida N, Ma MK, Rainbow K, Braun S, Patwary N, Yeo GSH, Klein CA, Perry ACF
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.15.298018
Epub:
Not Epub
Abstract:
Following fertilization, the new embryo reprograms parental genomes to begin transcription (embryonic genome activation, EGA)....
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Asami M, Lam BYH, Hoffmann M, Suzuki T, Lu X, VerMilyea MD, Yoshida N, Ma MK, Rainbow K, Braun S, Patwary N, Yeo GSH, Klein CA, Perry ACF. Mouse fertilization triggers a conserved transcription program in one-cell embryos. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.15.298018 .

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