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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Grb10a knockdown in Danio rerio during early life alters growth and cardiometabolic function associated with a remodelled transcriptome
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.06.413633 Epub:
Not Epub Abstract:
Embryonic growth trajectory is a risk factor for chronic metabolic and cardiovascular disorders and influences birth weight... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Evans B, Garner T, DeLeonibus C, Wearing O, Shiels H, Hurlstone AH, Clayton P, Stevens A. Grb10a knockdown in Danio rerio during early life alters growth and cardiometabolic function associated with a remodelled transcriptome. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.06.413633. |
Long noncoding RNAs implicated in embryonic development in Ybx1 knockout zebrafish
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Citation:
FEBS Open Bio. 2021 Apr;11(4):1259-1276. doi: 10.1002/2211-5463.13057 Epub:
Not Epub Abstract:
Y-box-binding protein 1 (Ybx1, YB-1), also known as Y-box transcription factor, is involved in a variety of biological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang C, Zhu B, Leng D, Ge W, Zhang XD. Long noncoding RNAs implicated in embryonic development in Ybx1 knockout zebrafish. FEBS Open Bio. 2021 Apr;11(4):1259-1276. doi: 10.1002/2211-5463.13057. |
Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
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Citation:
Nat Commun. 2020;11:6235. doi:10.1038/s41467-020-20023-4 Epub:
Not Epub Abstract:
The extensive array of morphological diversity among animal taxa represents the product of millions of years of evolution.... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Cary GA, McCauley BS, Zueva O, Pattinato J, Longabaugh W, Hinman VF. Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development. Nat Commun. 2020;11:6235. doi:10.1038/s41467-020-20023-4. |
Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication
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Citation:
Int J Molec Sci. 2020;21(23):1422-0067 doi:10.3390/ijms21239260 Epub:
Not Epub Abstract:
Current methods to detect and monitor pathogens in biological systems are largely limited by the tradeoffs between spatial... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Vero, BHK-21 Citation Extract: Victorio CB, Novera W, Tham JY, Watanabe S, Vasudevan SG, Chacko A-M. Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication. Int J Molec Sci. 2020;21(23):1422-0067 doi:10.3390/ijms21239260. |
The N-glycome regulates the endothelial-to-hematopoietic transition
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Citation:
Science. 2020:370(6521):1186-1191. doi:10.1126/science.aaz2121 Epub:
Not Epub Abstract:
Definitive hematopoietic stem and progenitor cells (HSPCs) arise from the transdifferentiation of hemogenic endothelial cells (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, William C. Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S. The N-glycome regulates the endothelial-to-hematopoietic transition. Science. 2020:370(6521):1186-1191. doi:10.1126/science.aaz2121. |
Unravelling the developmental and functional significance of an ancient Argonaute duplication
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Citation:
Nat Comm. 2020;11:6187. doi:10.1038/s41467-020-20003-8 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) base-pair to messenger RNA targets and guide Argonaute proteins to mediate their silencing. This target... Organism or Cell Type:
Nematostella vectensis (cniderian) Citation Extract: Fridrich A, Modepalli V, Lewandowska M, Aharoni R, Moran Y. Unravelling the developmental and functional significance of an ancient Argonaute duplication. Nat Comm. 2020;11:6187. doi:10.1038/s41467-020-20003-8. |
Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.01.404053 Epub:
Not Epub Abstract:
Histone tails are subject to various post-translational modifications, which play a fundamental role in altering chromatin... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis Citation Extract: Angerilli A, Tait J, Berges J, Shcherbakova I, Schauer T, Smialowski P, Hsam O, Mentele E, Nicetto D, Rupp RAW. Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.01.404053 . |
Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish
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Citation:
Biochem Biophys Res Commun. 2020 Nov 27:S0006-291X(20)32121-5. doi: 10.1016/j.bbrc.2020.11.077. Online ahead of print Epub:
Yes Abstract:
Paired Box (Pax) gene family, a group of transcription regulators have been implicated in diverse physiological processes.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pak B, Schmitt CE, Oh S, Kim JD, Choi W, Han O, Kim M, Kim MJ, Ham HJ, Kim S, Huh TL, Kim JI, Jin SW. Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish. Biochem Biophys Res Commun. 2020 Nov 27:S0006-291X(20)32121-5. doi: 10.1016/j.bbrc.2020.11.077. Online ahead of print. |
Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model for Phospholamban R14del cardiomyopathy
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.25.397422 Epub:
Not Epub Abstract:
The heterozygous phospholamban (PLN) p.Arg14del (R14del) mutation is found in patients with dilated or arrhythmogenic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kamel SM, van Opbergen CJM, Koopman CD, Verkerk AO, Onderwater YL, Chocron S, Polidoro Pontalti C, Vos MA, de Boer TP, van Veen TAB, Bakkers J. Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model for Phospholamban R14del cardiomyopathy. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.25.397422. |
Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.26.399626 Epub:
Not Epub Abstract:
Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y. Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.26.399626. |