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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish

Authors:
Takahashi K, Ito Y, Yoshimura M, Nikaido M, Yuikawa T, Kawamura A, Tsuda S, Kage D, Yamasu K
Citation:
Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print
Epub:
Yes
Abstract:
The zebrafish is an excellent model animal that is amenable to forward genetics approaches. To uncover unknown developmental...
Link:
https://pubmed.ncbi.nlm.nih.gov/33358912/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takahashi K, Ito Y, Yoshimura M, Nikaido M, Yuikawa T, Kawamura A, Tsuda S, Kage D, Yamasu K. A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish. Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print.

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1

Authors:
Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X
Citation:
Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5
Epub:
Not Epub
Abstract:
Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance...
Link:
https://www.nature.com/articles/s41392-020-00375-5
Organism or Cell Type:
cell culture: HepG2-SR
Citation Extract:
Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X. CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5.

ace2 expression is higher in intestines and liver while being tightly regulated in development and disease in zebrafish

Authors:
Ayse Gokce Keskus, Melike Tombaz, Burcin I. Arici, Fatma B. Dincaslan, Afshan Nabi, Huma Shehwana, Ozlen Konu
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.24.424209
Epub:
Not Epub
Abstract:
Human Angiotensin I Converting Enzyme 2 (ACE2) that acts as a receptor for SARS-CoV-2 entry is highly expressed in human type...
Link:
https://www.biorxiv.org/content/10.1101/2020.12.24.424209v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ayse Gokce Keskus, Melike Tombaz, Burcin I. Arici, Fatma B. Dincaslan, Afshan Nabi, Huma Shehwana, Ozlen Konu. ace2 expression is higher in intestines and liver while being tightly regulated in development and disease in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.24.424209.

Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice

Authors:
Li J, Liu Y, Li Q, Huang X, Zhou D, Xu H, Zhao F, Mi X, Wang R, Jia F, Xu F, Yang J, Liu D, Deng X, Zhang Y
Citation:
Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print
Epub:
Not Epub
Abstract:
Myoclonus dystonia syndrome (MDS) is an inherited movement disorder, and most MDS-related mutations have so far been found in...
Link:
https://link.springer.com/article/10.1007/s12264-020-00612-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Liu Y, Li Q, Huang X, Zhou D, Xu H, Zhao F, Mi X, Wang R, Jia F, Xu F, Yang J, Liu D, Deng X, Zhang Y. Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice. Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print.

Discovery and mechanistic characterization of a novel AhR receptor ligand that induces apoptosis in cancer cells

Authors:
O'Donnell E, Jang HS, Liefwalker D, Kerkvliet N, Kolluri SK
Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-131951/v1
Epub:
Not Epub
Abstract:
Background: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the bHLH/PAS (basic...
Link:
https://www.researchsquare.com/article/rs-131951/v1
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: Hepa 1
Citation Extract:
O'Donnell E, Jang HS, Liefwalker D, Kerkvliet N, Kolluri SK. Discovery and mechanistic characterization of a novel AhR receptor ligand that induces apoptosis in cancer cells. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-131951/v1.

Transcriptome Profile of the Sinoatrial Ring Reveals Conserved and Novel Genetic Programs of the Zebrafish Pacemaker

Authors:
Minhas R, Loeffler-Wirth H, Siddiqui Y, Obrebski T, Vhashist S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL
Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-130687/v1
Epub:
Not Epub
Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the...
Link:
https://www.researchsquare.com/article/rs-130687/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Minhas R, Loeffler-Wirth H, Siddiqui Y, Obrebski T, Vhashist S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome Profile of the Sinoatrial Ring Reveals Conserved and Novel Genetic Programs of the Zebrafish Pacemaker. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-130687/v1.

Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis

Authors:
Shi Y, Liu Z, Zhang Q, Vallee I, Mo Z, Kishi S, Yang X-L
Citation:
PLoS Biol. 2020;18(12):e3000991. doi:10.1371/journal.pbio.3000991
Epub:
Not Epub
Abstract:
Hypoxia-induced angiogenesis maintains tissue oxygen supply and protects against ischemia but also enhances tumor progression...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000991
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi Y, Liu Z, Zhang Q, Vallee I, Mo Z, Kishi S, Yang X-L. Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis. PLoS Biol. 2020;18(12):e3000991. doi:10.1371/journal.pbio.3000991.

osr1 maintains renal progenitors and regulates podocyte development by promoting wnt2ba through antagonism of hand2

Authors:
Drummond BE, Chambers BE, Wesselman HM, Ulrich MN, Gerlach GF, Kroeger PT, Leshchiner I, Goessling W, Wingert RA
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.21.423845
Epub:
Not Epub
Abstract:
Knowledge about the genetic pathways that control renal cell lineage development is essential to better understand the basis of...
Link:
https://www.biorxiv.org/content/10.1101/2020.12.21.423845v1.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Drummond BE, Chambers BE, Wesselman HM, Ulrich MN, Gerlach GF, Kroeger PT, Leshchiner I, Goessling W, Wingert RA. osr1 maintains renal progenitors and regulates podocyte development by promoting wnt2ba through antagonism of hand2. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.21.423845 .

Nrl is dispensable for specification of rod photoreceptors in adult zebrafish contrasting a deeply conserved requirement earlier in ontogeny

Authors:
Oel AP, Neil GJ, Dong EM, Balay SD, Collett K, Allison WT
Citation:
iScience. 2020;23(12):101805 doi:10.1016/j.isci.2020.101805
Epub:
Not Epub
Abstract:
The transcription factor NRL (neural retina leucine zipper) has been canonized as the master regulator of photoreceptor cell...
Link:
https://www.cell.com/iscience/fulltext/S2589-0042(20)31002-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oel AP, Neil GJ, Dong EM, Balay SD, Collett K, Allison WT. Nrl is dispensable for specification of rod photoreceptors in adult zebrafish contrasting a deeply conserved requirement earlier in ontogeny. iScience. 2020;23(12):101805 doi:10.1016/j.isci.2020.101805.

Transformed notochordal cells trigger chronic wounds destabilizing the vertebral column and bone homeostasis

Authors:
Lopez-Cuevas P, Deane L, Yang Y, Hammond CL, Kague E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.18.423470
Epub:
Not Epub
Abstract:
Notochordal cells play a pivotal role in vertebral column patterning, contributing to the formation of the inner architecture...
Link:
https://www.biorxiv.org/content/10.1101/2020.12.18.423470v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lopez-Cuevas P, Deane L, Yang Y, Hammond CL, Kague E. Transformed notochordal cells trigger chronic wounds destabilizing the vertebral column and bone homeostasis. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.18.423470 .

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