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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus

Authors:
Tsironis I, Paganos P, Gouvi G, Tsimpos P, Stamopoulou A, Arnone MI, Flytzanis CN
Citation:
Dev Biol. 2021 Jan 20:S0012-1606(20)30322-5. doi:10.1016/j.ydbio.2020.12.012. Online ahead of print
Epub:
Yes
Abstract:
Coup-TF, a member of the nuclear receptor super-family, is present in the pool of maternal mRNAs and proteins in the sea urchin...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160620303225
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Tsironis I, Paganos P, Gouvi G, Tsimpos P, Stamopoulou A, Arnone MI, Flytzanis CN. Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus. Dev Biol. 2021 Jan 20:S0012-1606(20)30322-5. doi:10.1016/j.ydbio.2020.12.012. Online ahead of print.

Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish

Authors:
Zhao L, Zhang B, Huang S, Zhou Z, Jia X, Qiao C, Wang F, Sun M, Shi Y, Yao L, Cui C, Shen Y
Citation:
Cell Mol Neurobiol. 2021 Jan 22. doi:10.1007/s10571-020-01022-x. Online ahead of print
Epub:
Not Epub
Abstract:
Insulin-like growth factor-1 (IGF-1) is a neurotrophic factor produced locally in the central nervous system which can promote...
Link:
https://link.springer.com/article/10.1007%2Fs10571-020-01022-x
Delivery Method:
lesion site
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao L, Zhang B, Huang S, Zhou Z, Jia X, Qiao C, Wang F, Sun M, Shi Y, Yao L, Cui C, Shen Y. Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish. Cell Mol Neurobiol. 2021 Jan 22. doi:10.1007/s10571-020-01022-x. Online ahead of print.

Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

Authors:
Ma J, Scott CA, Ho YN, Marsay KS, Zhang C, Teow CKJ, Ng SS, Zhang W, Tergaonkar V, Partridge LJ, Roy S, Amaya E, Carney TJ
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.21.427549
Epub:
Not Epub
Abstract:
Tissues respond to damage by increasing inflammation and epithelial cell motility. How damage detection and responses are...
Link:
https://www.biorxiv.org/content/10.1101/2021.01.21.427549v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma J, Scott CA, Ho YN, Marsay KS, Zhang C, Teow CKJ, Ng SS, Zhang W, Tergaonkar V, Partridge LJ, Roy S, Amaya E, Carney TJ. Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.21.427549.

Diversified Biomineralization Roles of Pteria penguin Pearl Shell Lectins as Matrix Proteins

Authors:
Ogawa T, Sato R, Naganuma T, Liu K, Sato S, Sakaue S, Osada M, Yoshimi K, Muramoto K
Citation:
Int J Mol Sci. 2021;22(3),1081. doi:10.3390/ijms22031081
Epub:
Not Epub
Abstract:
Previously, we isolated jacalin-related lectins termed PPL2, PPL3 (PPL3A, 3B and 3C) and PPL4 from the mantle secretory fluid...
Link:
https://www.mdpi.com/1422-0067/22/3/1081/htm
Delivery Method:
Endo-Porter
Organism or Cell Type:
Pteria penguin (oyster)
Citation Extract:
Ogawa T, Sato R, Naganuma T, Liu K, Sato S, Sakaue S, Osada M, Yoshimi K, Muramoto K. Diversified Biomineralization Roles of Pteria penguin Pearl Shell Lectins as Matrix Proteins. Int J Mol Sci. 2021;22(3),1081. doi:10.3390/ijms22031081.

A recurrent missense variant in EYA3 gene is associated with oculo-auriculo-vertebral spectrum

Authors:
Tingaud-Sequeira A, Trimouille A, Salaria M, Stapleton R, Claverol S, Plaisant C, Bonneu M, Lopez E, Arveiler B, Lacombe D, Rooryck C
Citation:
Hum Genet. 2021;[Epub ahead of print] doi:s00439-021-02255-6
Epub:
Yes
Abstract:
Goldenhar syndrome or oculo-auriculo-vertebral spectrum (OAVS) is a complex developmental disorder characterized by asymmetric...
Link:
https://link.springer.com/article/10.1007%2Fs00439-021-02255-6
Organism or Cell Type:
zebrafish
Citation Extract:
Tingaud-Sequeira A, Trimouille A, Salaria M, Stapleton R, Claverol S, Plaisant C, Bonneu M, Lopez E, Arveiler B, Lacombe D, Rooryck C. A recurrent missense variant in EYA3 gene is associated with oculo-auriculo-vertebral spectrum. Hum Genet. 2021;[Epub ahead of print] doi:s00439-021-02255-6.

LIM Homeobox 4 (lhx4) regulates retinal neural differentiation and visual function in zebrafish

Authors:
Guo R, Ge K, Wang Y, Lu M, Li F, Tian L, Gan L, Sheng D
Citation:
Sci Rep. 2021;11:1977. doi:10.1038/s41598-021-81211-w
Epub:
Not Epub
Abstract:
LIM homeobox 4 (LHX4) is expressed in the photoreceptors (PRs) of the outer nuclear layer (ONL) and bipolar cells (BCs) of the...
Link:
https://www.nature.com/articles/s41598-021-81211-w
Delivery Method:
microinjection, Vivo-Morpholino (ocular injection)
Organism or Cell Type:
zebrafish
Citation Extract:
Guo R, Ge K, Wang Y, Lu M, Li F, Tian L, Gan L, Sheng D. LIM Homeobox 4 (lhx4) regulates retinal neural differentiation and visual function in zebrafish. Sci Rep. 2021;11:1977. doi:10.1038/s41598-021-81211-w.

Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia

Authors:
Brastrom LK, Scott CA, Wang K, Slusarski DC
Citation:
Biomedicines. 2021;9(2):100. doi:10.3390/biomedicines9020100
Epub:
Not Epub
Abstract:
Congenital eye defects represent a large class of disorders affecting roughly 21 million children worldwide. Microphthalmia and...
Link:
https://www.mdpi.com/2227-9059/9/2/100
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brastrom LK, Scott CA, Wang K, Slusarski DC. Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia. Biomedicines. 2021;9(2):100. doi:10.3390/biomedicines9020100.

Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome

Authors:
Lee S, Shin CH, Lee J, Jeong SD, Hong CY, Kim J-D, Kim A-R, Son SJ, Kokhan O, Yoo T, Ko JS, Sohn YB, Kim O-H, Ko JM, Cho T-J, Wright NT, Seong JK, Jin S-W, Kang HJ, Kim HH, Choi M
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/483362
Epub:
Not Epub
Abstract:
Shwachman-Diamond syndrome (SDS; OMIM: #260400) is caused by variants in SBDS (Shwachman-Bodian-Diamond syndrome gene), which...
Link:
https://www.biorxiv.org/content/10.1101/483362v5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S, Shin CH, Lee J, Jeong SD, Hong CY, Kim J-D, Kim A-R, Son SJ, Kokhan O, Yoo T, Ko JS, Sohn YB, Kim O-H, Ko JM, Cho T-J, Wright NT, Seong JK, Jin S-W, Kang HJ, Kim HH, Choi M. Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome. bioRxiv. 2021;[preprint] doi:10.1101/483362.

Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos

Authors:
Cafora M, Forti F, Briani F, Ghisotti D, Pistocchi A
Citation:
J Vis Exp. 2020;(159):e61275. doi:10.3791/61275
Epub:
Not Epub
Abstract:
Antimicrobial resistance, a major consequence of diagnostic uncertainty and antimicrobial overprescription, is an increasingly...
Link:
https://www.jove.com/t/61275/phage-therapy-application-to-counteract-pseudomonas-aeruginosa
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cafora M, Forti F, Briani F, Ghisotti D, Pistocchi A. Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos. J Vis Exp. 2020;(159):e61275. doi:10.3791/61275 .

An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy

Authors:
Pagnamenta AT, Kaiyrzhanov R, Zou Y, Da'as SI, Maroofian R, Donkervoort S, Dominik N, Lauffer M, Ferla MP, Orioli A, Giess A, Tucci A, Beetz C, Sedghi M, Ansari B, Barresi R, Basiri K, Cortese A, Elgar G, Fernandez-Garcia MA, Yip J, Foley AR, Gutowski N, Jungbluth H, Lassche S, Lavin T, Marcelis C, Marks P, Marini-Bettolo C, Medne L, Moslemi A-R, Sarkozy A, Reilly MM, Muntoni F, Millan F, Muraresku CC, Need AC, Nemeth AH, Neuhaus SB, Norwood F, O'Donnell M, O’Driscoll M, Rankin J, Yum SW, Zolkipli-Cunningham Z, Brusius I, Wunderlich G, Genomics England Research Consortium, Karakaya M, Wirth B, Fakhro KA, Tajsharghi H, Bönnemann CG, Taylor JC, Houlden H
Citation:
Brain. 2021;[Epub ahead of print] doi:10.1093/brain/awaa420
Epub:
Yes
Abstract:
The extracellular matrix comprises a network of macromolecules such as collagens, proteoglycans and glycoproteins. VWA1 (von...
Link:
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaa420/6103826
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pagnamenta AT, Kaiyrzhanov R, Zou Y, Da'as SI, Maroofian R, Donkervoort S, Dominik N, Lauffer M, Ferla MP, Orioli A, Giess A, Tucci A, Beetz C, Sedghi M, Ansari B, Barresi R, Basiri K, Cortese A, Elgar G, Fernandez-Garcia MA, Yip J, Foley AR, Gutowski N, Jungbluth H, Lassche S, Lavin T, Marcelis C, Marks P, Marini-Bettolo C, Medne L, Moslemi A-R, Sarkozy A, Reilly MM, Muntoni F, Millan F, Muraresku CC, Need AC, Nemeth AH, Neuhaus SB, Norwood F, O'Donnell M, O’Driscoll M, Rankin J, Yum SW, Zolkipli-Cunningham Z, Brusius I, Wunderlich G, Genomics England Research Consortium, Karakaya M, Wirth B, Fakhro KA, Tajsharghi H, Bönnemann CG, Taylor JC, Houlden H. An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy. Brain. 2021;[Epub ahead of print] doi:10.1093/brain/awaa420.

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