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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Cytoskeletal Protein Zyxin Inhibits the Activity of Genes Responsible for Embryonic Stem Cell Status
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Citation:
Cell Rep. 2020;33(7):108396. doi:10.1016/j.celrep.2020.108396 Epub:
Not Epub Abstract:
Zyxin is a cytoskeletal LIM-domain protein that regulates actin cytoskeleton assembly and gene expression. In the present work... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis and zebrafish Citation Extract: Parshina EA, Eroshkin FM, Оrlov EE, Gyoeva FK, Shokhina AG, Staroverov DB, Belousov VV, Zhigalova NA, Prokhortchouk EB, Zaraisky AG, Martynova NY. Cytoskeletal Protein Zyxin Inhibits the Activity of Genes Responsible for Embryonic Stem Cell Status. Cell Rep. 2020;33(7):108396. doi:10.1016/j.celrep.2020.108396. |
Zebrafish Cdx1b modulates epithalamic asymmetry by regulating ndr2 and lft1 expression
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Citation:
Dev Biol. 2020 Nov 13:S0012-1606(20)30293-1. doi: 10.1016/j.ydbio.2020.11.001. Online ahead of print Epub:
Yes Abstract:
Nodal signaling is essential for mesoderm and endoderm formation, as well as neural plate induction and establishment of left-... Delivery Method:
microinjection, Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Wu CS, Lu YF, Liu YH, Huang CJ, Hwang SL. Zebrafish Cdx1b modulates epithalamic asymmetry by regulating ndr2 and lft1 expression. Dev Biol. 2020 Nov 13:S0012-1606(20)30293-1. doi: 10.1016/j.ydbio.2020.11.001. Online ahead of print. |
GJA1 Depletion Causes Ciliary Defects by Affecting Rab11 Trafficking to the Ciliary Base
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.13.381764 Epub:
Not Epub Abstract:
The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Jang DG, Kwon KY, Kweon YC, Kim B-g, Myung K, Lee H-S, Park CY, Kwon T, Park TJ. GJA1 Depletion Causes Ciliary Defects by Affecting Rab11 Trafficking to the Ciliary Base. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.13.381764 . |
Pcdh18a-positive tip cells instruct notochord formation in zebrafish
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Citation:
bioRxiv. 2018;[preprint] doi:10.1101/257717 Epub:
Not Epub Abstract:
The notochord defines the axial structure of all vertebrates during development. Notogenesis is a result of major cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bosze B, Mattes B, Sinner C, Stricker K, Gourain V, Thumberger T, Tlili S, Weber S, Wittbrodt J, Saunders TE, Strähle U, Schug A, Scholpp S. Pcdh18a-positive tip cells instruct notochord formation in zebrafish. bioRxiv. 2018;[preprint] doi:10.1101/257717. |
RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis
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Citation:
Nat Commun. 2020;11:5816 doi:10.1038/s41467-020-19658-0 Epub:
Not Epub Abstract:
Primary microcephaly (MCPH) is characterized by reduced brain size and intellectual disability. The exact pathophysiological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Farooq M, Lindbæk L, Krogh N, Doganli C, Keller C, Mönnich M, Gonçalves AB, Sakthivel S, Mang Y, Fatima A, Andersen VS, Hussain MS, Eiberg H, Hansen L, Kjaer KW, Gopalakrishnan J, Pedersen LB, Møllgård K, Nielsen H, Baig SM, Tommerup N, Christensen ST, Larsen LA. RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis. Nat Commun. 2020;11:5816 doi:10.1038/s41467-020-19658-0. |
Investigating the effect of DMD non-sequential splicing on exon skipping strategies
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Citation:
Neuromuscul Disord. 2020;30(Suppl 1):S128-S129. P.281 doi:10.1016/j.nmd.2020.08.278 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy is one of the most common myopathies, with an incidence of 1:5000 in new-born boys. The root cause... Organism or Cell Type:
cell culture: myocytes Citation Extract: Goossens R, Verwey N, Schnell F, Aartsma-Rus A. Investigating the effect of DMD non-sequential splicing on exon skipping strategies. Neuromuscul Disord. 2020;30(Suppl 1):S128-S129. P.281 doi:10.1016/j.nmd.2020.08.278. |
Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.
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Citation:
Front Cell Infect Microbiol. 2020 Oct 29;10:519503. doi: 10.3389/fcimb.2020.519503 Epub:
Not Epub Abstract:
The ADP ribosylation factor (ARF) GTPase activation protein ASAP1 possesses multiple biological functions, including regulation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cui J, Chen G, Wen D, Wang Y, Zhao Z, Wu C. Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.. Front Cell Infect Microbiol. 2020 Oct 29;10:519503. doi: 10.3389/fcimb.2020.519503. |
The Caudal ParaHox gene is required for hindgut development in the mollusc Tritia (a.k.a. Ilyanassa)
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Citation:
Dev Biol. 2020 Oct 24;470:1-9. doi: 10.1016/j.ydbio.2020.10.010. Online ahead of print Epub:
Not Epub Abstract:
Caudal homeobox genes are found across animals, typically linked to two other homeobox genes in what has been called the... Organism or Cell Type:
Tritia obsoleta (previously Ilyanassa obsoleta) gastropod Citation Extract: Johnson AB, Lambert JD. The Caudal ParaHox gene is required for hindgut development in the mollusc Tritia (a.k.a. Ilyanassa). Dev Biol. 2020 Oct 24;470:1-9. doi: 10.1016/j.ydbio.2020.10.010. Online ahead of print. |
Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells
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Citation:
Nanomedicine. 2020;[Epub] doi:10.1016/j.nano.2020.102332 Epub:
Not Epub Abstract:
Human diabetic corneas develop delayed wound healing, epithelial stem cell dysfunction, recurrent erosions, and keratitis.... Delivery Method:
nanopolymer Organism or Cell Type:
cell culture: diabetic limbal epithelial cells; organ culture: cornea Citation Extract: Kramerov AA, Shah R, Ding H, Holler E, Turjman S, Rabinowitz YS, Ghiam S, Maguen E, Svendsen CN, Saghizadeh M, Ljubimova JY, Ljubimov AV. Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells. Nanomedicine. 2020;[Epub] doi:10.1016/j.nano.2020.102332. |
The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina
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Citation:
Cell Rep. 2020 Nov 10;33(6):108360. doi: 10.1016/j.celrep.2020.108360 Epub:
Not Epub Abstract:
Expansion of a CAG repeat in ATXN3 causes the dominant polyglutamine disease spinocerebellar ataxia type 3 (SCA3), yet the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Toulis V, García-Monclús S, de la Peña-Ramírez C, Arenas-Galnares R, Abril JF, Todi SV, Khan N, Garanto A, Costa MDC, Marfany G. The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina. Cell Rep. 2020 Nov 10;33(6):108360. doi: 10.1016/j.celrep.2020.108360. |