You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Transcriptional regulation of EMT by nuclear MMP28

Authors:
Gouignard N, Bibonne A, Saint-Jeannet J-P, Theveneau E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.19.389544
Epub:
Not Epub
Abstract:
Epithelial-Mesenchymal Transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.19.389544v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Bibonne A, Saint-Jeannet J-P, Theveneau E. Transcriptional regulation of EMT by nuclear MMP28. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.19.389544 .

Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h

Authors:
Espanola SG, Song H, Ryu E, Saxena A, Kim E-S, Manegold JE, Nasamran CA, Sahoo D, Oh C-K, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang M-S, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-00604-7
Epub:
Yes
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) have been the focus of developmental and regenerative studies, yet our...
Link:
https://www.nature.com/articles/s41556-020-00604-7
Organism or Cell Type:
zebrafish
Citation Extract:
Espanola SG, Song H, Ryu E, Saxena A, Kim E-S, Manegold JE, Nasamran CA, Sahoo D, Oh C-K, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang M-S, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-00604-7.

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells

Authors:
Jin L, Chen Y, Crossman DK, Datta A, Vu T, Mobley JA, Basu MK, Scarduzio M, Wang H, Chang C, Datta PK
Citation:
Nat Comm. 2020;11(1):5941. doi:10.1038/s41467-020-19698-6
Epub:
Not Epub
Abstract:
Alternative splicing (AS) is involved in cell fate decisions and embryonic development. However, regulation of these processes...
Link:
https://www.nature.com/articles/s41467-020-19698-6
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jin L, Chen Y, Crossman DK, Datta A, Vu T, Mobley JA, Basu MK, Scarduzio M, Wang H, Chang C, Datta PK. STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells. Nat Comm. 2020;11(1):5941. doi:10.1038/s41467-020-19698-6.

PDE10A inhibition reduces the manifestation of pathology in DMD zebrafish and represses the genetic modifier PITPNA

Authors:
Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM
Citation:
Mol Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.11.021
Epub:
Yes
Abstract:
Duchenne Muscular Dystrophy (DMD) is a severe genetic disorder caused by mutations in the DMD gene. Absence of dystrophin...
Link:
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(20)30619-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM. PDE10A inhibition reduces the manifestation of pathology in DMD zebrafish and represses the genetic modifier PITPNA. Mol Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.11.021.

The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network

Authors:
Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.185827
Epub:
Yes
Abstract:
\Understanding how complex organ systems are assembled from simple embryonic tissues is a major challenge. Across the animal...
Link:
https://dev.biologists.org/content/early/2020/11/15/dev.185827
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
cell culture: Gallus gallus (chick) somite tissue
Citation Extract:
Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE. The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network. Development. 2020;[Epub ahead of print] doi:10.1242/dev.185827.

Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis

Authors:
Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P
Citation:
Genes. 2020:11(11):2073-4425. doi:10.3390/genes11111363
Epub:
Not Epub
Abstract:
Gastrulation drives the establishment of three germ layers and embryonic axes during frog embryonic development. Mesodermal...
Link:
https://www.mdpi.com/2073-4425/11/11/1363/htm
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P. Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis. Genes. 2020:11(11):2073-4425. doi:10.3390/genes11111363.

Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching

Authors:
Kundu T, Das SS, Kumar DS, Sewatkar LK, Ghose A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.16.384099
Epub:
Not Epub
Abstract:
Interstitial collateral branching of axons is a critical component in the development of functional neural circuits. Axon...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.16.384099v1
Organism or Cell Type:
cell culture: chick spinal neurons
Citation Extract:
Kundu T, Das SS, Kumar DS, Sewatkar LK, Ghose A. Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.16.384099.

PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia

Authors:
Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, Sawa A, Wetsel WC, Werge T, Katsanis N
Citation:
Nat Comm. 2020;11:5903. doi:10.1038/s41467-020-19637-5
Epub:
Not Epub
Abstract:
The neuronal primary cilium and centriolar satellites have functions in neurogenesis, but little is known about their roles in...
Link:
https://www.nature.com/articles/s41467-020-19637-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, Sawa A, Wetsel WC, Werge T, Katsanis N. PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. Nat Comm. 2020;11:5903. doi:10.1038/s41467-020-19637-5.

Tension heterogeneity directs form and fate to pattern the myocardial wall

Authors:
Priya R, Allanki S, Gentile A, Mansingh S, Uribe V, Maischein H-M, Stainier DYR
Citation:
Nature. 2020;[Epub ahead of print] doi:10.1038/s41586-020-2946-9
Epub:
Yes
Abstract:
How diverse cell fates and complex forms emerge and feed back to each other to sculpt functional organs remains unclear. In the...
Link:
https://www.nature.com/articles/s41586-020-2946-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Priya R, Allanki S, Gentile A, Mansingh S, Uribe V, Maischein H-M, Stainier DYR. Tension heterogeneity directs form and fate to pattern the myocardial wall. Nature. 2020;[Epub ahead of print] doi:10.1038/s41586-020-2946-9.

RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish

Authors:
Raman R, Ryon M, Jagadeeswaran P
Citation:
Sci Rep. 2020;10:20187 doi:10.1038/s41598-020-76655-5
Epub:
Not Epub
Abstract:
We recently developed a piggyback knockdown method that was used to knockdown genes in adult zebrafish. In this method, a vivo...
Link:
https://www.nature.com/articles/s41598-020-76655-5
Delivery Method:
Vivo-Morpholino (piggyback )
Organism or Cell Type:
zebrafish
Citation Extract:
Raman R, Ryon M, Jagadeeswaran P. RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish. Sci Rep. 2020;10:20187 doi:10.1038/s41598-020-76655-5.

Pages