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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Integrin intra-heterodimer affinity inversely correlates with integrin activatability
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Citation:
Cell Rep. 2021;35(10):109230. doi:10.1016/j.celrep.2021.109230 Epub:
Not Epub Abstract:
Integrins are heterodimeric cell surface receptors composed of an α and β subunit that mediate cell adhesion to extracellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun G, Guillon E, Holley SA. Integrin intra-heterodimer affinity inversely correlates with integrin activatability. Cell Rep. 2021;35(10):109230. doi:10.1016/j.celrep.2021.109230. |
eSkip-Finder: a machine learning-based web application and database to identify the optimal sequences of antisense oligonucleotides for exon skipping
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Citation:
Nucl Acids Res. 2021;[Epub ahead of print] doi:10.1093/nar/gkab442 Epub:
Yes Abstract:
Exon skipping using antisense oligonucleotides (ASOs) has recently proven to be a powerful tool for mRNA splicing modulation.... Organism or Cell Type:
cell culture: primary human myotubes Citation Extract: Chiba S, Lim KRQ, Sheri N, Anwar S, Erkut E, Shah MNA, Aslesh T, Woo S, Sheikh O, Maruyama R, Takano H, Kunitake K, Duddy W, Okuno Y, Aoki Y, Yokota T. eSkip-Finder: a machine learning-based web application and database to identify the optimal sequences of antisense oligonucleotides for exon skipping. Nucl Acids Res. 2021;[Epub ahead of print] doi:10.1093/nar/gkab442. |
Early inflammation dysregulates neuronal circuit formation in vivo via upregulation of IL-1β
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Citation:
J Neurosci. 2021 Jun 8:JN-RM-2159-20. doi: 10.1523/JNEUROSCI.2159-20.2021. Online ahead of print Epub:
Yes Abstract:
Neuro-immune interaction during development is strongly implicated in the pathogenesis of neurodevelopmental disorders, but the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Solek CM, Farooqi NAI, Brake N, Kesner P, Schohl A, Antel JP, Ruthazer ES. Early inflammation dysregulates neuronal circuit formation in vivo via upregulation of IL-1β. J Neurosci. 2021 Jun 8:JN-RM-2159-20. doi: 10.1523/JNEUROSCI.2159-20.2021. Online ahead of print. |
A precise regulation of presenilin expression is required for the sea urchin early development
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Citation:
J Cell Sci. 2021;jcs.258382. doi:10.1242/jcs.258382 Epub:
Not Epub Abstract:
Presenilins or PSENs homologues are widely expressed across eukaryotes. Two PSEN are expressed in humans where they play a... Organism or Cell Type:
sea urchin Citation Extract: Bronchain O, Philippe-Caraty L, Anquetil V, Ciapa B. A precise regulation of presenilin expression is required for the sea urchin early development. J Cell Sci. 2021;jcs.258382. doi:10.1242/jcs.258382. |
Three-dimensional folding dynamics of the Xenopus tropicalis genome
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Citation:
Nat Genet. 2021;[Epub ahead of print] doi:10.1038/s41588-021-00878-z Epub:
Yes Abstract:
Animal interphase chromosomes are organized into topologically associating domains (TADs). How TADs are formed is not fully... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Niu L, Shen W, Shi Z, Tan Y, He N, Wan J, Sun J, Zhang Y, Huang Y, Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Li L, Hou C. Three-dimensional folding dynamics of the Xenopus tropicalis genome. Nat Genet. 2021;[Epub ahead of print] doi:10.1038/s41588-021-00878-z. |
[Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]
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Citation:
Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6 Epub:
Not Epub Abstract:
Donepezil, the most widely used drug for the treatment of Alzheimer's disease (AD), is an acetylcholinesterase (AChE)... Organism or Cell Type:
cell culture: primary fetal rat cortical neurons Citation Extract: Takada-Takatori Y. [Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]. Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6. |
Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos
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Citation:
In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5 Epub:
Not Epub Abstract:
The regulation of reproduction in zebrafish, the prime model of fish research, is not fully understood. An efficient tool to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Orbán L, Saju JM, Tzung KW, Liew WC. Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos. In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5. |
Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage
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Citation:
J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054 Epub:
Not Epub Abstract:
Neutrophil recruitment to tissue damage is essential for host defense but can also impede tissue repair. The cues that... Organism or Cell Type:
zebrafish Citation Extract: Houseright RA, Miskolci V, Mulvaney O, Bortnov V, Mosher DF, Rindy J, Bennin DA, Huttenlocher A. Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage. J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054. |
A Novel BLOC1S5-Related HPS-11 Patient and Zebrafish with bloc1s5 Disruption
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Citation:
Pigment Cell Melanoma Res. 2021 May 31. doi: 10.1111/pcmr.12995. Online ahead of print Epub:
Yes Abstract:
HPS (Hermansky-Pudlak Syndrome) cases present with a variable degree of OCA and bleeding tendency. HPS is categorized into... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhong Z, Wu Z, Zhang J, Chen J. A Novel BLOC1S5-Related HPS-11 Patient and Zebrafish with bloc1s5 Disruption. Pigment Cell Melanoma Res. 2021 May 31. doi: 10.1111/pcmr.12995. Online ahead of print. |
Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish
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Citation:
Front Cell Dev Biol. 2021 May 11;9:663995. doi: 10.3389/fcell.2021.663995. eCollection 2021 Epub:
Not Epub Abstract:
Hereditary hearing loss caused by defective hair cells is one of the most common congenital diseases, whose nosogenesis is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gong J, Qian P, Hu Y, Guo C, Wei G, Wang C, Cai C, Wang H, Liu D. Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish. Front Cell Dev Biol. 2021 May 11;9:663995. doi: 10.3389/fcell.2021.663995. eCollection 2021. |