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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

LIM Homeobox 9 Knockdown by Morpholino does not Affect Zebrafish Retinal Development

Authors:
Guo R, Li F, Lu M, Ge K, Gan L, Sheng D
Citation:
Bio Open. 2021:bio.056382 doi:10.1242/bio.056382
Epub:
Not Epub
Abstract:
LIM homeobox 9 (Lhx9) is a member of the LIM homeodomain transcription factor family, which expresses and functions in various...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo R, Li F, Lu M, Ge K, Gan L, Sheng D. LIM Homeobox 9 Knockdown by Morpholino does not Affect Zebrafish Retinal Development. Bio Open. 2021:bio.056382 doi:10.1242/bio.056382.

Transformed notochordal cells trigger chronic wounds destabilizing the vertebral column and bone homeostasis

Authors:
López-Cuevas P, Deane L, Yang Y, Hammond CL, Kague E
Citation:
Dis Model Mech. 2021;dmm.047001 doi:10.1242/dmm.047001
Epub:
Yes
Abstract:
Notochordal cells play a pivotal role in vertebral column patterning, contributing to the formation of the inner architecture...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
López-Cuevas P, Deane L, Yang Y, Hammond CL, Kague E. Transformed notochordal cells trigger chronic wounds destabilizing the vertebral column and bone homeostasis. Dis Model Mech. 2021;dmm.047001 doi:10.1242/dmm.047001.

Chemokine-biased robust self-organizing polarization of migrating cells in vivo

Authors:
Olguin-Olguin A, Aalto A, Maugis B, Boquet-Pujadas A, Hoffmann D, Ermlich L, Betz T, Gov NS, Reichman-Fried M, Raz E
Citation:
Proc Natl Acad Sci USA. 2021;118(7);e2018480118 doi:10.1073/pnas.2018480118
Epub:
Not Epub
Abstract:
To study the mechanisms controlling front-rear polarity in migrating cells, we used zebrafish primordial germ cells (PGCs) as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Olguin-Olguin A, Aalto A, Maugis B, Boquet-Pujadas A, Hoffmann D, Ermlich L, Betz T, Gov NS, Reichman-Fried M, Raz E. Chemokine-biased robust self-organizing polarization of migrating cells in vivo. Proc Natl Acad Sci USA. 2021;118(7);e2018480118 doi:10.1073/pnas.2018480118.

Retinol Binding Protein 1 Affects Xenopus Anterior Neural Development via All-trans Retinoic Acid Signalling

Authors:
Flach H, Basten T, Schreiner C, Dietmann P, Greco S, Nies L, Roßmanith N, Walter S, Kühl M, Kühl SJ
Citation:
Dev Dyn. 2021 Feb 11. doi: 10.1002/dvdy.313. Online ahead of print
Epub:
Not Epub
Abstract:
Background: Retinol binding protein 1 (Rbp1) acts as an intracellular regulator of vitamin A metabolism and retinoid transport...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Flach H, Basten T, Schreiner C, Dietmann P, Greco S, Nies L, Roßmanith N, Walter S, Kühl M, Kühl SJ. Retinol Binding Protein 1 Affects Xenopus Anterior Neural Development via All-trans Retinoic Acid Signalling. Dev Dyn. 2021 Feb 11. doi: 10.1002/dvdy.313. Online ahead of print.

sGC activity and regulation of blood flow in a Zebrafish model system

Authors:
Vishnolia KK, Rakovic A, Hoene C, Tarhbalouti K, Aherrahrou Z, Erdmann J
Citation:
Front Physiol. 2021;[provisional] doi: 10.3389/fphys.2021.633171
Epub:
Yes
Abstract:
Soluble guanylyl cyclase (sGC) protein is a heterodimer formed by two subunits encoded by the GUCY1A1 and GUCY1B1 genes. The...
Organism or Cell Type:
zebrafish
Citation Extract:
Vishnolia KK, Rakovic A, Hoene C, Tarhbalouti K, Aherrahrou Z, Erdmann J. sGC activity and regulation of blood flow in a Zebrafish model system. Front Physiol. 2021;[provisional] doi: 10.3389/fphys.2021.633171.

Computational Simulation of 4-D Micro-Circular Network in Zebrafish Tail Amputation and Regeneration

Authors:
Roustaei M, Baek KI, Wang Z, Cavallero S, Satta S, Lai A, O'Donnell R, Vedula V, Ding Y, Marsden AL, Hsiai T
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.10.430654
Epub:
Not Epub
Abstract:
Wall shear stress (WSS) in micro-vasculature contributes to biomechanical cues to regulate mechanotransduction underlying...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roustaei M, Baek KI, Wang Z, Cavallero S, Satta S, Lai A, O'Donnell R, Vedula V, Ding Y, Marsden AL, Hsiai T. Computational Simulation of 4-D Micro-Circular Network in Zebrafish Tail Amputation and Regeneration. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.10.430654 .

Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning

Authors:
Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P
Citation:
Nat Methods. 2021. doi:10.1038/s41592-021-01058-x
Epub:
Not Epub
Abstract:
Light-field microscopy has emerged as a technique of choice for high-speed volumetric imaging of fast biological processes....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P. Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning. Nat Methods. 2021. doi:10.1038/s41592-021-01058-x.

Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish

Authors:
Sengupta A, Padhan DK, Ganguly A, Sen M
Citation:
Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409
Epub:
Not Epub
Abstract:
Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Sengupta A, Padhan DK, Ganguly A, Sen M. Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish. Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409.

Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation

Authors:
Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fernández-Rodriguez J, Blanco I, Castellanos E, Carrió M, Lazaro C, Serra E
Citation:
Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w
Epub:
Not Epub
Abstract:
Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: PC12
Citation Extract:
Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fernández-Rodriguez J, Blanco I, Castellanos E, Carrió M, Lazaro C, Serra E. Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation. Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w.

Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides

Authors:
Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y
Citation:
Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease caused by frameshift or nonsense mutations in the DMD gene...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture:CXMDJ immortalized myoblasts
Citation Extract:
Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y. Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides. Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print.

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