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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation

Authors:
Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E
Citation:
Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693
Epub:
Not Epub
Abstract:
Integrated molecular signals regulate cell fate decisions in the embryonic aortic endothelium to drive hematopoietic stem cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E. Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation. Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693.

Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme

Authors:
Abu NK, Migdał M, Quinn TA, Poon K-L, Łapinski M, Sulej A, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428386
Epub:
Not Epub
Abstract:
The atrioventricular canal (AVC) is an essential feature of the heart, which separates the atrium from the ventricle. During...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Abu NK, Migdał M, Quinn TA, Poon K-L, Łapinski M, Sulej A, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C. Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428386.

Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction

Authors:
Weng S, Huebner RJ, Wallingford JB
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.12.426405
Epub:
Not Epub
Abstract:
Convergent extension is an evolutionarily conserved collective cell movement that elongates the body axis of all animals and is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Weng S, Huebner RJ, Wallingford JB. Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.12.426405 .

Eya1-dependent homeostasis of morphogenetic territories during collective cell migration

Authors:
Miranda-Rodríguez JR, Borges A, Pinto-Teixeira F, Wibowo I, Pogoda H-M, Hammerschmidt M, Kawakami K, López-Schier H
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428404
Epub:
Not Epub
Abstract:
Tissue remodeling presents an enormous challenge to the stability of intercellular signaling domains. Here we investigate this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miranda-Rodríguez JR, Borges A, Pinto-Teixeira F, Wibowo I, Pogoda H-M, Hammerschmidt M, Kawakami K, López-Schier H. Eya1-dependent homeostasis of morphogenetic territories during collective cell migration. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428404 .

Slit2 is necessary for optic axon organization in the zebrafish ventral midline

Authors:
Davison C, Zolessi FR
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.09.25.314062
Epub:
Not Epub
Abstract:
The functional connection of the retina with the brain implies the extension of retinal ganglion cells axons through a long and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davison C, Zolessi FR. Slit2 is necessary for optic axon organization in the zebrafish ventral midline. bioRxiv 2020;[preprint] doi:10.1101/2020.09.25.314062 .

Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility

Authors:
Romanos M, Allio G, Combres L, Médevielle F, Escalas N, Soula C, Steventon B, Trescases A, Bénazéraf
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611
Epub:
Not Epub
Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Coturnix japonica (quail) embryo
Citation Extract:
Romanos M, Allio G, Combres L, Médevielle F, Escalas N, Soula C, Steventon B, Trescases A, Bénazéraf. Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611 .

Tacc3 modulates microtubule network dynamicity and focal adhesion remodeling to affect cranial neural crest cell migration in Xenopus laevis

Authors:
Bearce EA, Pratt B, Rutherford EL, Carandang LA, Lowery L
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430297
Epub:
Not Epub
Abstract:
Coordinated cell migration is critical during embryogenesis, as cells must leave their point of origin, navigate a complex...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bearce EA, Pratt B, Rutherford EL, Carandang LA, Lowery L. Tacc3 modulates microtubule network dynamicity and focal adhesion remodeling to affect cranial neural crest cell migration in Xenopus laevis. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430297 .

Bidirectional neuronal migration coordinates retinal morphogenesis by preventing spatial competition

Authors:
Rocha-Martins M, Kretzschmar J, Nerli E, Weigert M, Icha J, Myers EW, Norden C
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430189
Epub:
Not Epub
Abstract:
While the design of industrial products is often optimized for the sequential assembly of single components, organismal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rocha-Martins M, Kretzschmar J, Nerli E, Weigert M, Icha J, Myers EW, Norden C. Bidirectional neuronal migration coordinates retinal morphogenesis by preventing spatial competition. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430189.

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

Authors:
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M
Citation:
eLife. 2021;10:e59067 doi:10.7554/eLife.59067
Epub:
Not Epub
Abstract:
Genetic variants associated with type 2 diabetes (T2D) risk affect gene regulation in metabolically relevant tissues, such as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. eLife. 2021;10:e59067 doi:10.7554/eLife.59067.

l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Authors:
Soliman R, Cordero-Maldonado ML, Martins TG, Moein M, Conrotte JF, Warmack RA, Skupin A, Crawford AD, Clarke SG, Linster CL
Citation:
Front Genet. 2021 Jan 21;11:612343. doi: 10.3389/fgene.2020.612343. eCollection 2020
Epub:
Not Epub
Abstract:
Isomerization of l-aspartyl and l-asparaginyl residues to l-isoaspartyl residues is one type of protein damage that can occur...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Soliman R, Cordero-Maldonado ML, Martins TG, Moein M, Conrotte JF, Warmack RA, Skupin A, Crawford AD, Clarke SG, Linster CL. l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain. Front Genet. 2021 Jan 21;11:612343. doi: 10.3389/fgene.2020.612343. eCollection 2020.

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