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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

Mvda is required for zebrafish early development

Authors:
Wong W, Huang Y, Wu Z, Kong Y, Luan J, Zhang Q, Pan J, Yan K, Zhang Z
Citation:
Biol Res. 2021 May 29;54(1):17. doi: 10.1186/s40659-021-00341-7
Epub:
Not Epub
Abstract:
Background: The MVD gene mutations are identified in porokeratosis, which is considered a skin-specific autoinflammatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong W, Huang Y, Wu Z, Kong Y, Luan J, Zhang Q, Pan J, Yan K, Zhang Z. Mvda is required for zebrafish early development. Biol Res. 2021 May 29;54(1):17. doi: 10.1186/s40659-021-00341-7.

Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies

Authors:
Dworschak GC, Punetha J, Kalanithy JC, Mingardo E, Erdem HB, Akdemir ZC, Karaca E, Mitani T, Marafi D, Fatih JM, Jhangiani SN, Hunter JV, Dakal TC, Dhabhai B, Dabbagh O, Alsaif HS, Alkuraya FS, Maroofian R, Houlden H, Efthymiou S, Dominik N, Salpietro V, Sultan T, Haider S, Bibi F, Thiele H, Hoefele J, Riedhammer KM, Wagner M, Guella I, Demos M, Keren B, Buratti J, Charles P, Nava C, Héron D, Heide S, Valkanas E, Waddell LB, Jones KJ, Oates EC, Cooper ST, MacArthur D, Syrbe S, Ziegler A, Platzer K, Okur V, Chung WK, O'Shea SA, Alcalay R, Fahn S, Mark PR, Guerrini R, Vetro A, Hudson B, Schnur RE, Hoganson GE, Burton JE, McEntagart M, Lindenberg T, Yilmaz Ö, Odermatt B, Pehlivan D, Posey JE, Lupski JR, Reutter H
Citation:
Genet Med. 2021 May 30. doi: 10.1038/s41436-021-01196-9. Online ahead of print
Epub:
Not Epub
Abstract:
Purpose: To investigate the effect of PLXNA1 variants on the phenotype of patients with autosomal dominant and recessive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dworschak GC, Punetha J, Kalanithy JC, Mingardo E, Erdem HB, Akdemir ZC, Karaca E, Mitani T, Marafi D, Fatih JM, Jhangiani SN, Hunter JV, Dakal TC, Dhabhai B, Dabbagh O, Alsaif HS, Alkuraya FS, Maroofian R, Houlden H, Efthymiou S, Dominik N, Salpietro V, Sultan T, Haider S, Bibi F, Thiele H, Hoefele J, Riedhammer KM, Wagner M, Guella I, Demos M, Keren B, Buratti J, Charles P, Nava C, Héron D, Heide S, Valkanas E, Waddell LB, Jones KJ, Oates EC, Cooper ST, MacArthur D, Syrbe S, Ziegler A, Platzer K, Okur V, Chung WK, O'Shea SA, Alcalay R, Fahn S, Mark PR, Guerrini R, Vetro A, Hudson B, Schnur RE, Hoganson GE, Burton JE, McEntagart M, Lindenberg T, Yilmaz Ö, Odermatt B, Pehlivan D, Posey JE, Lupski JR, Reutter H. Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies. Genet Med. 2021 May 30. doi: 10.1038/s41436-021-01196-9. Online ahead of print.

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family

Authors:
Mathieu H, Patten SA, Aragon-Martin JA, Ocaka L, Simpson M, Child A, Moldovan F
Citation:
Sci Rep. 2021 May 26;11(1):11026. doi: 10.1038/s41598-021-90155-0
Epub:
Not Epub
Abstract:
Idiopathic scoliosis (IS) is a complex 3D deformation of the spine with a strong genetic component, most commonly found in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathieu H, Patten SA, Aragon-Martin JA, Ocaka L, Simpson M, Child A, Moldovan F. Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family. Sci Rep. 2021 May 26;11(1):11026. doi: 10.1038/s41598-021-90155-0.

CX3CR1 is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats

Authors:
Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S
Citation:
J Virol. 2021 Jul 26;95(16):e0001021. doi: 10.1128/JVI.00010-21. Epub 2021 Jul 26. PMID: 34037420; PMCID: PMC8312862
Epub:
Not Epub
Abstract:
Respiratory syncytial virus (RSV) has been reported to use CX3CR1 in vitro as a receptor on cultured primary human airway...
Delivery Method:
peptide-linked
Organism or Cell Type:
Sigmodon sp. (Cotton rat)
Citation Extract:
Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S. CX3CR1 is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats. J Virol. 2021 Jul 26;95(16):e0001021. doi: 10.1128/JVI.00010-21. Epub 2021 Jul 26. PMID: 34037420; PMCID: PMC8312862.

Rab35 regulates skeletogenesis and gastrulation by facilitating actin remodeling and vesicular trafficking

Authors:
Remsburg C, Testa M, Song JL
Citation:
Cells Dev. 2021 Mar;165:203660. doi: 10.1016/j.cdev.2021.203660. Epub 2021 Jan 18
Epub:
Not Epub
Abstract:
Rab35 is a small GTPase that regulates plasma membrane to early endosome vesicular trafficking and mediates actin remodeling to...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Remsburg C, Testa M, Song JL. Rab35 regulates skeletogenesis and gastrulation by facilitating actin remodeling and vesicular trafficking. Cells Dev. 2021 Mar;165:203660. doi: 10.1016/j.cdev.2021.203660. Epub 2021 Jan 18.

FASCIN regulates actin assembly for spindle movement and polar body extrusion in mouse oocyte meiosis

Authors:
Hu LL, Pan MH, Yang FL, Zong ZA, Tang F, Pan ZN, Lu X, Ren YP, Wang JL, Sun SC
Citation:
J Cell Physiol. 2021 May 21. doi: 10.1002/jcp.30443. Online ahead of print
Epub:
Not Epub
Abstract:
During mouse oocyte meiotic maturation, actin filaments play multiple roles in meiosis such as spindle migration and...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hu LL, Pan MH, Yang FL, Zong ZA, Tang F, Pan ZN, Lu X, Ren YP, Wang JL, Sun SC. FASCIN regulates actin assembly for spindle movement and polar body extrusion in mouse oocyte meiosis. J Cell Physiol. 2021 May 21. doi: 10.1002/jcp.30443. Online ahead of print.

Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations

Authors:
Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH
Citation:
Elife. 2021 May 20;10:e62155. doi: 10.7554/eLife.62155. Online ahead of print
Epub:
Not Epub
Abstract:
Mosaic inactivation of CCM2 in humans causes cerebral cavernous malformations (CCMs) containing adjacent dilated blood-filled...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 May 20;10:e62155. doi: 10.7554/eLife.62155. Online ahead of print.

Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism

Authors:
Sun F, Fang Y, Zhang MM, Zhang RJ, Wu FY, Yang RM, Tu PH, Dong M, Zhao SX, Song HD
Citation:
Endocrinology. 2021 May 21:bqab101. doi: 10.1210/endocr/bqab101. Online ahead of print
Epub:
Yes
Abstract:
Congenital hypothyroidism (CH) is a highly prevalent but treatable neonatal endocrine disorder. Thyroid dyshormonogenesis is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun F, Fang Y, Zhang MM, Zhang RJ, Wu FY, Yang RM, Tu PH, Dong M, Zhao SX, Song HD. Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism. Endocrinology. 2021 May 21:bqab101. doi: 10.1210/endocr/bqab101. Online ahead of print.

Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models

Authors:
Heller IS, Guenther CA, Meireles AM, Talbot WS, Kingsley DM
Citation:
Bone. 2022 Feb;155:116263. doi: 10.1016/j.bone.2021.116263. Epub 2021 Nov 23. PMID: 34826632; PMCID: PMC9007314
Epub:
Not Epub
Abstract:
Many key signaling molecules used to build tissues during embryonic development are re-activated at injury sites to stimulate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heller IS, Guenther CA, Meireles AM, Talbot WS, Kingsley DM. Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models. Bone. 2022 Feb;155:116263. doi: 10.1016/j.bone.2021.116263. Epub 2021 Nov 23. PMID: 34826632; PMCID: PMC9007314.

Interferon tau: Influences on growth and development of the conceptus

Authors:
Bazer FW, Seo H, Wu G, Johnson GA
Citation:
Theriogenology. 2020;150:75-83. doi:10.1016/j.theriogenology.2020.01.069
Epub:
Not Epub
Abstract:
Interferon tau (IFNT), the pregnancy recognition signal secreted from trophectoderm cells of ruminant conceptuses abrogates the...
Organism or Cell Type:
Ovis aries (sheep) conceptus
Citation Extract:
Bazer FW, Seo H, Wu G, Johnson GA. Interferon tau: Influences on growth and development of the conceptus. Theriogenology. 2020;150:75-83. doi:10.1016/j.theriogenology.2020.01.069.

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