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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Dpysl2 (CRMP2) is required for the migration of facial branchiomotor neurons in the developing zebrafish embryo

Authors:
Fiallos-Oliveros C, Ohshima T
Citation:
Int J Dev Biol. 2020;64(10-11-12):479-484. doi: 10.1387/ijdb.190375to
Epub:
Not Epub
Abstract:
Dihydropyrimidinase-like family proteins (Dpysls) are relevant in several processes during nervous system development; among...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fiallos-Oliveros C, Ohshima T. Dpysl2 (CRMP2) is required for the migration of facial branchiomotor neurons in the developing zebrafish embryo. Int J Dev Biol. 2020;64(10-11-12):479-484. doi: 10.1387/ijdb.190375to.

Kcnb1 plays a role in development of the inner ear

Authors:
Jedrychowska J, Gasanov EV, Korzha V
Citation:
Dev Biol. 2021;471:65-75. doi:10.1016/j.ydbio.2020.12.007
Epub:
Not Epub
Abstract:
The function of the inner ear depends on the maintenance of high concentrations of K+ ions. The slow-inactivating delayed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jedrychowska J, Gasanov EV, Korzha V. Kcnb1 plays a role in development of the inner ear. Dev Biol. 2021;471:65-75. doi:10.1016/j.ydbio.2020.12.007.

Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification

Authors:
Mao A, Zhang M, Li L, Liu J, Ning G, Cao Y, Wang Q
Citation:
Development. 2020;148: dev192658 [Epub ahead of print] doi:10.1242/dev.192658
Epub:
Yes
Abstract:
The paired pharyngeal arch arteries (PAAs) are transient blood vessels connecting the heart with the dorsal aorta during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mao A, Zhang M, Li L, Liu J, Ning G, Cao Y, Wang Q. Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification. Development. 2020;148: dev192658 [Epub ahead of print] doi:10.1242/dev.192658.

Histone Demethylase PHF8 Is Required for the Development of the Zebrafish Inner Ear and Posterior Lateral Line

Authors:
He J, Zheng Z, Luo X, Hong Y, Su W, Cai C
Citation:
Front Cell Dev Biol. 2020 Nov 23;8:566504. doi: 10.3389/fcell.2020.566504. eCollection 2020
Epub:
Not Epub
Abstract:
Histone demethylase PHF8 is crucial for multiple developmental processes, and hence, the awareness of its function in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He J, Zheng Z, Luo X, Hong Y, Su W, Cai C. Histone Demethylase PHF8 Is Required for the Development of the Zebrafish Inner Ear and Posterior Lateral Line. Front Cell Dev Biol. 2020 Nov 23;8:566504. doi: 10.3389/fcell.2020.566504. eCollection 2020.

Transferrin receptor (TFRC) is essential for meiotic progression during mouse spermatogenesis

Authors:
Gao T, Lin M, Wu Y, Li K, Liu C, Zhou Q, Shen C, Zheng B, Huang X
Citation:
Zygote. 2020 Dec 16:1-7. doi:10.1017/S0967199420000659
Epub:
Not Epub
Abstract:
Meiosis is a highly conserved process, and is responsible for the production of haploid gametes and generation of genetic...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: mouse testis explants
Citation Extract:
Gao T, Lin M, Wu Y, Li K, Liu C, Zhou Q, Shen C, Zheng B, Huang X. Transferrin receptor (TFRC) is essential for meiotic progression during mouse spermatogenesis. Zygote. 2020 Dec 16:1-7. doi:10.1017/S0967199420000659.

TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production

Authors:
Ratliff ML, Shankar M, Guthridge JM, James JA, Webb CF
Citation:
Cell Immunol. 2020 Nov;357:104201. doi: 10.1016/j.cellimm.2020.104201. Epub 2020 Sep 9
Epub:
Not Epub
Abstract:
The DNA binding protein AT-rich interacting domain 3a (ARID3a)2 is expressed in healthy human hematopoietic cord blood...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: human hematopoietic stem progenitor cells (HSPCs)
Citation Extract:
Ratliff ML, Shankar M, Guthridge JM, James JA, Webb CF. TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNalpha production. Cell Immunol. 2020 Nov;357:104201. doi: 10.1016/j.cellimm.2020.104201. Epub 2020 Sep 9.

The tight junctions protein Claudin-5 limits endothelial cell motility

Authors:
Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Stephan A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J
Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.248237
Epub:
Yes
Abstract:
Steinberg's differential adhesion hypothesis suggests that adhesive mechanisms are important for sorting of cells and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Stephan A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J. The tight junctions protein Claudin-5 limits endothelial cell motility. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.248237.

The RNA helicase DDX3 induces neural crest by promoting AKT activity

Authors:
Perfetto M, Xu X, Lu C, Shi Y, Yousaf N, Li J, Yien YY, Wei S
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.184341
Epub:
Not Epub
Abstract:
Mutations in the RNA helicase DDX3 have emerged as a frequent cause of intellectual disability in humans. Because many patients...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Perfetto M, Xu X, Lu C, Shi Y, Yousaf N, Li J, Yien YY, Wei S. The RNA helicase DDX3 induces neural crest by promoting AKT activity. Development. 2020;[Epub ahead of print] doi:10.1242/dev.184341.

16p12.1 deletion orthologs are expressed in motile neural crest cells and are important for regulating craniofacial development in Xenopus laevis

Authors:
Lasser M, Bolduc J, Murphy L, O'Brien C, Lee S, Girirajan S, Lowery L
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.12.11.421347
Epub:
Not Epub
Abstract:
Copy number variants (CNVs) associated with neurodevelopmental disorders are characterized by extensive phenotypic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lasser M, Bolduc J, Murphy L, O'Brien C, Lee S, Girirajan S, Lowery L. 16p12.1 deletion orthologs are expressed in motile neural crest cells and are important for regulating craniofacial development in Xenopus laevis. bioRxiv. 2020;[preprint] doi:10.1101/2020.12.11.421347 .

Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis

Authors:
Lee H, Ismail T, Kim Y, Chae S, Ryu H-Y, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S
Citation:
Antioxidants 2020;9(12):1265. doi:10.3390/antiox9121265
Epub:
Not Epub
Abstract:
Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and is a key antioxidant enzyme...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lee H, Ismail T, Kim Y, Chae S, Ryu H-Y, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis. Antioxidants 2020;9(12):1265. doi:10.3390/antiox9121265.

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