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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo
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Citation:
Development. 2021;dev.191197 doi:10.1242/dev.191197 Epub:
Yes Abstract:
Activation of Wnt/β-catenin (cWnt) signaling at the future posterior end of early bilaterian embryos is a highly conserved... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus & Lytechinus variegatus (sea urchin) Citation Extract: Sun H, Peng CFJ, Wang L, Feng H, Wikramanayake AH
. An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo. Development. 2021;dev.191197 doi:10.1242/dev.191197. |
Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss
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Citation:
JCI Insight. 2021 Mar 8;6(5):141561. doi: 10.1172/jci.insight.141561 Epub:
Not Epub Abstract:
Hair cell loss is the leading cause of hearing and balance disorders in humans. It can be caused by many factors, including... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zallocchi M, Hati S, Xu Z, Hausman W, Liu H, He DZ, Zuo J. Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss. JCI Insight. 2021 Mar 8;6(5):141561. doi: 10.1172/jci.insight.141561. |
The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.04.433320 Epub:
Not Epub Abstract:
The enpp ectonucleotidases regulate lipidic and purinergic signalling pathways by controlling the extracellular concentrations... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA. The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.04.433320. |
Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
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Citation:
PLoS Genet. 2021;17(3):e1009263. doi:10.1371/journal.pgen.1009263 Epub:
Not Epub Abstract:
Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y. Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation. PLoS Genet. 2021;17(3):e1009263. doi:10.1371/journal.pgen.1009263. |
Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models
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Citation:
EBioMedicine. 2021;65:103263. doi:10.1016/j.ebiom.2021.103263 Epub:
Not Epub Abstract:
Background: We developed a preclinical protocol for the screening of candidate drugs able to control myopia and prevent its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin M-Y, Lin I-T, Wu Y-C, Wang I-J. Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models. EBioMedicine. 2021;65:103263. doi:10.1016/j.ebiom.2021.103263. |
Conditional gene knockdowns in sea urchins using caged morpholinos
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Citation:
Dev Biol . 2021 Mar 5;475:21-29. doi: 10.1016/j.ydbio.2021.02.014 Epub:
Not Epub Abstract:
Sea urchins and other echinoderms are important experimental models for analyzing embryonic development, but a lack of spatial... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Bardhan A, Deiters A, Ettensohn CA. Conditional gene knockdowns in sea urchins using caged morpholinos. Dev Biol . 2021 Mar 5;475:21-29. doi: 10.1016/j.ydbio.2021.02.014. |
The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy
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Citation:
Ann Clin Transl Neurol. 2021 Mar 8. doi: 10.1002/acn3.51336. Online ahead of print Epub:
Not Epub Abstract:
Objectives: To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA... Delivery Method:
s.c. (subcutaneous) injection Organism or Cell Type:
severe SMA mice Citation Extract: Spicer C, Lu CH, Catapano F, Scoto M, Zaharieva I, Malaspina A, Morgan JE, Greensmith L, Muntoni F, Zhou H. The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy. Ann Clin Transl Neurol. 2021 Mar 8. doi: 10.1002/acn3.51336. Online ahead of print. |
Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish
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Citation:
BMC Dev Biol. 2021 Mar 8;21(1):7. doi: 10.1186/s12861-021-00238-4 Epub:
Not Epub Abstract:
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castellanos BS, Reyes-Nava NG, Quintana AM. Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish. BMC Dev Biol. 2021 Mar 8;21(1):7. doi: 10.1186/s12861-021-00238-4. |
Na+/H+-exchangers differentially contribute to midgut fluid sodium and proton concentration in the sea urchin larva
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Citation:
J Exp Biol. 2021 Apr 1;224(7):jeb240705. doi: 10.1242/jeb.240705. Epub 2021 Apr 15 Epub:
Not Epub Abstract:
Regulation of ionic composition and pH is a requisite of all digestive systems in the animal kingdom. Larval stages of the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Petersen I, Chang WWJ, Hu MY. Na+/H+-exchangers differentially contribute to midgut fluid sodium and proton concentration in the sea urchin larva. J Exp Biol. 2021 Apr 1;224(7):jeb240705. doi: 10.1242/jeb.240705. Epub 2021 Apr 15. |
Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus
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Citation:
Russ J Bioorg Chem. 2019;45(6):774-782. doi:10.1134/S1068162019060268 Epub:
Not Epub Abstract:
The paper reports the synthesis of a series of antisense oligonucleotides (aONs) directed against different segments of the... Delivery Method:
Endo-Porter, scrape delivery Organism or Cell Type:
cell culture: (H1N1)/MDCK, (H1N1)/A549 influenza in cells Citation Extract: Markov AV, Kupryushkin MS, Goncharova EP, Amirkhanov RN, Vasilyeva SV, Pyshnyi DV, Zenkova MA, Logashenko EB. Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus. Russ J Bioorg Chem. 2019;45(6):774-782. doi:10.1134/S1068162019060268. |