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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

Authors:
Buchan KD, van Gent M, Prajsnar TK, Ogryzko NV, de Jong NWM, Kolata J, Foster SJ, van Strijp JAG, Renshaw SA
Citation:
J Cell Sci. 2021;134:jcs252205 doi:10.1242/jcs.252205
Epub:
Not Epub
Abstract:
Staphylococcus aureus infects ∼30% of the human population and causes a spectrum of pathologies ranging from mild skin...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Buchan KD, van Gent M, Prajsnar TK, Ogryzko NV, de Jong NWM, Kolata J, Foster SJ, van Strijp JAG, Renshaw SA. Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model. J Cell Sci. 2021;134:jcs252205 doi:10.1242/jcs.252205.

Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA-Hybridization Properties

Authors:
Hofmeister A, Jahn-Hofmann K, Krack A, Müller A, Kurz M, Scheidler S
Citation:
Chembiochem. 2020 Oct 28. doi: 10.1002/cbic.202000693
Epub:
Not Epub
Abstract:
A novel class of nucleotide analogues with a dioxane ring as central scaffold has been developed. Synthetic routes in two...
Citation Extract:
Hofmeister A, Jahn-Hofmann K, Krack A, Müller A, Kurz M, Scheidler S. Novel Dioxane and Morpholino Nucleotide Analogues: Syntheses and RNA-Hybridization Properties. Chembiochem. 2020 Oct 28. doi: 10.1002/cbic.202000693.

Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis

Authors:
Chandrakar P, Seth A, Rani A, Dutta M, Parmar N, Descoteaux A, Kar S
Citation:
J Cell Sci. 2021;134:jcs252494 doi:10.1242/jcs.252494
Epub:
Not Epub
Abstract:
Notch signaling governs crucial aspects of intercellular communication spanning antigen-presenting cells and T-cells. In this...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Balb/c mice and sometimes Leishmania donovani infections
Citation Extract:
Chandrakar P, Seth A, Rani A, Dutta M, Parmar N, Descoteaux A, Kar S. Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis. J Cell Sci. 2021;134:jcs252494 doi:10.1242/jcs.252494 .

Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates

Authors:
Rossin F, Costa R, Bordi M, D’Eletto M, Occhigrossi L, Farrace MG, Barlev N, Ciccosanti F, Muccioli S, Chieregato L, Szabo I, Fimia GM, Piacentini M, Leanza L
Citation:
Cell Death Dis. 2021;12(3):249. doi:10.1038/s41419-021-03485-2
Epub:
Not Epub
Abstract:
TG2 is a multifunctional enzyme involved in several cellular processes and has emerging as a potential regulator of gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rossin F, Costa R, Bordi M, D’Eletto M, Occhigrossi L, Farrace MG, Barlev N, Ciccosanti F, Muccioli S, Chieregato L, Szabo I, Fimia GM, Piacentini M, Leanza L. Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates. Cell Death Dis. 2021;12(3):249. doi:10.1038/s41419-021-03485-2.

Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos

Authors:
Hatte G, Prigent C, Tassan J-P
Citation:
Exp Cell Res. 2021:112525. doi:10.1016/j.yexcr.2021.112525
Epub:
Not Epub
Abstract:
Cells dividing in the plane of epithelial tissues proceed by polarized constriction of the actomyosin contractile ring, leading...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hatte G, Prigent C, Tassan J-P. Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos. Exp Cell Res. 2021:112525. doi:10.1016/j.yexcr.2021.112525.

Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation

Authors:
Dastpeyman M, Karas JA, Amin A, Turner BJ, Shabanpoor F
Citation:
Front Chem. 2021;9:9. doi:10.3389/fchem.2021.627329
Epub:
Not Epub
Abstract:
Cell penetrating peptides (CPPs) are being increasingly used as efficient vectors for intracellular delivery of biologically...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: spinal muscular atrophy (SMA) patient fibroblasts
Citation Extract:
Dastpeyman M, Karas JA, Amin A, Turner BJ, Shabanpoor F. Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation. Front Chem. 2021;9:9. doi:10.3389/fchem.2021.627329.

hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies

Authors:
Alexander MS, Hightower RM, Reid AL, Bennett AH, Iyer L, Slonim DK, Saha M, Kawahara G, Kunkel LM, Kopin AS, Gupta VA, Kang PB, Draper I
Citation:
Muscle Nerve. 2021 Mar 2. doi: 10.1002/mus.27216. Online ahead of print
Epub:
Yes
Abstract:
Introduction/aims: RNA binding proteins (RBPs) play an important role in skeletal muscle development and disease by regulating...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alexander MS, Hightower RM, Reid AL, Bennett AH, Iyer L, Slonim DK, Saha M, Kawahara G, Kunkel LM, Kopin AS, Gupta VA, Kang PB, Draper I. hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies. Muscle Nerve. 2021 Mar 2. doi: 10.1002/mus.27216. Online ahead of print.

Tdrd3 regulates the progression of meiosis II through translational control of Emi2 mRNA in mouse oocytes

Authors:
Takei N, Sato K, Takada Y, Iyyappan R, Susor A, Yamamoto T, Kotani T
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.17.431574
Epub:
Not Epub
Abstract:
After completion of meiosis I, the oocyte immediately enters meiosis II and forms a metaphase II (MII) spindle without an...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Takei N, Sato K, Takada Y, Iyyappan R, Susor A, Yamamoto T, Kotani T. Tdrd3 regulates the progression of meiosis II through translational control of Emi2 mRNA in mouse oocytes. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.17.431574.

Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos

Authors:
Du J, Li SK, Guan L-Y, Guo Z, Yin J-F, Gao L, Kawanishi T, Shimada A, Zhang Q-p, Zheng L-S, Liu Y-Y, Feng X-X, Chen D-Y, Takeda H, Fan Y
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.25.432863
Epub:
Not Epub
Abstract:
The left-right symmetry breaking of vertebrate embryos requires fluid flow (called nodal flow in zebrafish). However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Du J, Li SK, Guan L-Y, Guo Z, Yin J-F, Gao L, Kawanishi T, Shimada A, Zhang Q-p, Zheng L-S, Liu Y-Y, Feng X-X, Chen D-Y, Takeda H, Fan Y. Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.25.432863 .

Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism

Authors:
Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg CP, Concha ML
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.24.432660
Epub:
Not Epub
Abstract:
The developmental strategies used by progenitor cells to endure a safe journey from their induction place towards the site of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg CP, Concha ML. Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.24.432660 .

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