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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
The SCF/KIT pathway implements self-organised epithelial patterning by cell movement
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Citation:
Dev Cell. 2021;56(6):795-810. doi:10.1016/j.devcel.2021.02.026 Epub:
Not Epub Abstract:
How global patterns emerge from individual cell behaviors is poorly understood. In the Xenopus embryonic epidermis,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Chuyen A, Rulquin C, Thome V, Clement R, Kodjabachian L, Pasini A. The SCF/KIT pathway implements self-organised epithelial patterning by cell movement. Dev Cell. 2021;56(6):795-810. doi:10.1016/j.devcel.2021.02.026. |
Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection
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Citation:
Nucleic Acids Res. 2021 Apr 19; 49(7): 3907–3918. doi:10.1093/nar/gkab152. Epub:
Yes Abstract:
Somatic expansion of the CAG repeat tract that causes Huntington's disease (HD) is thought to contribute to the rate of... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: human primary fibroblasts, mice Citation Extract: Roy JCL, Vitalo A, Andrew MA, Mota-Silva E, Kovalenko M, Burch Z, Nhu AM, Cohen PE, Grabczyk E, Wheeler VC, Mouro Pinto R. Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection. Nucleic Acids Res. 2021 Apr 19; 49(7): 3907–3918. doi:10.1093/nar/gkab152.. |
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development
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Citation:
Theranostics. 2021 Feb 25;11(9):4316-4334. doi: 10.7150/thno.51745. eCollection 2021 Epub:
Not Epub Abstract:
Trio is a unique member of the Rho-GEF family that has three catalytic domains and is vital for various cellular processes in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guo S, Meng L, Liu H, Yuan L, Zhao N, Ni J, Zhang Y, Ben J, Li YP, Ma J. Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development. Theranostics. 2021 Feb 25;11(9):4316-4334. doi: 10.7150/thno.51745. eCollection 2021. |
Furry is required for cell movements during gastrulation and functionally interacts with NDR1
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Citation:
Sci Rep. 2021;11(1):6607. doi:10.1038/s41598-021-86153-x Epub:
Not Epub Abstract:
Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Cervino AS, Moretti B, Stuckenholz C, Grecco HE, Davidson LA, Cirio MC. Furry is required for cell movements during gastrulation and functionally interacts with NDR1. Sci Rep. 2021;11(1):6607. doi:10.1038/s41598-021-86153-x. |
Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression
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Citation:
Front Oncol. 2021;11:440. doi:10.3389/fonc.2021.622263 Epub:
Not Epub Abstract:
Background: Hepatocellular carcinoma (HCC) is the most common primary liver tumor, and the main reason is the unclear... Delivery Method:
Lipofectamine 2000 Organism or Cell Type:
cell culture: HepG2 Citation Extract: Zhang H-Y, Liang H-X, Wu S-H, Jiang H-Q, Wang Q, Yu Z-J. Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression. Front Oncol. 2021;11:440. doi:10.3389/fonc.2021.622263. |
Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency
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Citation:
Sci Rep. 2021;11(1):6506. doi:10.1038/s41598-021-85704-6 Epub:
Not Epub Abstract:
Gonadotropin administration during infertility treatment stimulates the growth and development of multiple ovarian follicles,... Delivery Method:
microinjection Organism or Cell Type:
Macaca mulatta (rhesus macaque) oocyte Citation Extract: Ravisankar S, Brooks KE, Murphy MJ, Redmayne N, Ryu J, Kinchen JM, Chavez SL, Hennebold JD. Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency. Sci Rep. 2021;11(1):6506. doi:10.1038/s41598-021-85704-6. |
NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis
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Citation:
PLoS Genet. 2021;17(3):e1009402. doi:10.1371/journal.pgen.1009402 Epub:
Not Epub Abstract:
Impaired formation of the intrahepatic biliary network leads to cholestatic liver diseases, which are frequently associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ghaffari K, Pierce LX, Roufaeil M, Gibson I, Tae K, Sahoo S, Cantrell JT, Andersson O, Lau J, Sakaguchi TF. NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis. PLoS Genet. 2021;17(3):e1009402. doi:10.1371/journal.pgen.1009402. |
Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.13.435246 Epub:
Not Epub Abstract:
We report the discovery that flow and Svep1 are modulator of vessel anastomosis during developmental angiogenesis in zebrafish... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Coxam B, Padberg Y, Maier K, Jung S, Bartels-Klein E, Szymborska A, Finotto L, Helker CSM, Stainier DYR, Schulte-Merker S, Gerhardt H. Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.13.435246 . |
Dram1 confers resistance to Salmonella infection
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.21.436194 Epub:
Not Epub Abstract:
Dram1 is a stress and infection inducible autophagy modulator that functions downstream of transcription factors p53 and NFκB.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Masud S, Zhang R, Prajsnar TK, Meijer AH. Dram1 confers resistance to Salmonella infection. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.21.436194. |
Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency
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Citation:
Genet Med. 2021. doi:10.1038/s41436-021-01137-6 Epub:
Not Epub Abstract:
Purpose: Variants in NUS1 are associated with a congenital disorder of glycosylation, developmental and epileptic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu S-H, Wang T, Wiggins K, Louie RJ, Merino EF, Skinner C, Cassera MB, Meagher K, Goldberg P, Rismanchi N, Chen D, Lyons MJ, Flanagan-Steet H, Steet R. Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency. Genet Med. 2021. doi:10.1038/s41436-021-01137-6. |