You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Eya1-dependent homeostasis of morphogenetic territories during collective cell migration

Authors:
Miranda-Rodríguez JR, Borges A, Pinto-Teixeira F, Wibowo I, Pogoda H-M, Hammerschmidt M, Kawakami K, López-Schier H
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428404
Epub:
Not Epub
Abstract:
Tissue remodeling presents an enormous challenge to the stability of intercellular signaling domains. Here we investigate this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miranda-Rodríguez JR, Borges A, Pinto-Teixeira F, Wibowo I, Pogoda H-M, Hammerschmidt M, Kawakami K, López-Schier H. Eya1-dependent homeostasis of morphogenetic territories during collective cell migration. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428404 .

Slit2 is necessary for optic axon organization in the zebrafish ventral midline

Authors:
Davison C, Zolessi FR
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.09.25.314062
Epub:
Not Epub
Abstract:
The functional connection of the retina with the brain implies the extension of retinal ganglion cells axons through a long and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davison C, Zolessi FR. Slit2 is necessary for optic axon organization in the zebrafish ventral midline. bioRxiv 2020;[preprint] doi:10.1101/2020.09.25.314062 .

Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility

Authors:
Romanos M, Allio G, Combres L, Médevielle F, Escalas N, Soula C, Steventon B, Trescases A, Bénazéraf
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611
Epub:
Not Epub
Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Coturnix japonica (quail) embryo
Citation Extract:
Romanos M, Allio G, Combres L, Médevielle F, Escalas N, Soula C, Steventon B, Trescases A, Bénazéraf. Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611 .

Tacc3 modulates microtubule network dynamicity and focal adhesion remodeling to affect cranial neural crest cell migration in Xenopus laevis

Authors:
Bearce EA, Pratt B, Rutherford EL, Carandang LA, Lowery L
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430297
Epub:
Not Epub
Abstract:
Coordinated cell migration is critical during embryogenesis, as cells must leave their point of origin, navigate a complex...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bearce EA, Pratt B, Rutherford EL, Carandang LA, Lowery L. Tacc3 modulates microtubule network dynamicity and focal adhesion remodeling to affect cranial neural crest cell migration in Xenopus laevis. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430297 .

Bidirectional neuronal migration coordinates retinal morphogenesis by preventing spatial competition

Authors:
Rocha-Martins M, Kretzschmar J, Nerli E, Weigert M, Icha J, Myers EW, Norden C
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430189
Epub:
Not Epub
Abstract:
While the design of industrial products is often optimized for the sequential assembly of single components, organismal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rocha-Martins M, Kretzschmar J, Nerli E, Weigert M, Icha J, Myers EW, Norden C. Bidirectional neuronal migration coordinates retinal morphogenesis by preventing spatial competition. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.08.430189.

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

Authors:
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M
Citation:
eLife. 2021;10:e59067 doi:10.7554/eLife.59067
Epub:
Not Epub
Abstract:
Genetic variants associated with type 2 diabetes (T2D) risk affect gene regulation in metabolically relevant tissues, such as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. eLife. 2021;10:e59067 doi:10.7554/eLife.59067.

l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Authors:
Soliman R, Cordero-Maldonado ML, Martins TG, Moein M, Conrotte JF, Warmack RA, Skupin A, Crawford AD, Clarke SG, Linster CL
Citation:
Front Genet. 2021 Jan 21;11:612343. doi: 10.3389/fgene.2020.612343. eCollection 2020
Epub:
Not Epub
Abstract:
Isomerization of l-aspartyl and l-asparaginyl residues to l-isoaspartyl residues is one type of protein damage that can occur...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Soliman R, Cordero-Maldonado ML, Martins TG, Moein M, Conrotte JF, Warmack RA, Skupin A, Crawford AD, Clarke SG, Linster CL. l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain. Front Genet. 2021 Jan 21;11:612343. doi: 10.3389/fgene.2020.612343. eCollection 2020.

Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine

Authors:
Faundes V, Jennings MD, Crilly S, Legraie S, Withers SE, Cuvertino S, Davies SJ, Douglas AGL, Fry AE, Harrison V, Amiel J, Lehalle D, Newman WG, Newkirk P, Ranells J, Splitt M, Cross LA, Saunders CJ, Sullivan BR, Granadillo JL, Gordon CT, Kasher PR, Pavitt GD, Banka S
Citation:
Nat Commun. 2021 Feb 5;12(1):833. doi: 10.1038/s41467-021-21053-2
Epub:
Not Epub
Abstract:
The structure of proline prevents it from adopting an optimal position for rapid protein synthesis. Poly-proline-tract (PPT)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Faundes V, Jennings MD, Crilly S, Legraie S, Withers SE, Cuvertino S, Davies SJ, Douglas AGL, Fry AE, Harrison V, Amiel J, Lehalle D, Newman WG, Newkirk P, Ranells J, Splitt M, Cross LA, Saunders CJ, Sullivan BR, Granadillo JL, Gordon CT, Kasher PR, Pavitt GD, Banka S. Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine. Nat Commun. 2021 Feb 5;12(1):833. doi: 10.1038/s41467-021-21053-2.

Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk

Authors:
Bastos de Oliveira M, Meier K, Jung S, Bartels-Klein E, Coxam B, Geudens I, Szymborska A, Skoczylas R, Fechner I, Koltowska K, Gerhardt H
Citation:
Development. 2021 Feb 5:dev.194993. doi: 10.1242/dev.194993. Online ahead of print
Epub:
Not Epub
Abstract:
Previous studies have shown that Vasohibin-1 (Vash1) is stimulated by VEGFs in endothelial cells and that its overexpression...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bastos de Oliveira M, Meier K, Jung S, Bartels-Klein E, Coxam B, Geudens I, Szymborska A, Skoczylas R, Fechner I, Koltowska K, Gerhardt H. Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk. Development. 2021 Feb 5:dev.194993. doi: 10.1242/dev.194993. Online ahead of print.

SNRNP200 Mutations Cause Autosomal Dominant Retinitis Pigmentosa

Authors:
Zhang T, Bai J, Zhang X, Zheng X, Lu N, Liang Z, Lin L, Chen Y
Citation:
Front Med (Lausanne). 2021 Jan 21;7:588991. doi: 10.3389/fmed.2020.588991
Epub:
Not Epub
Abstract:
The small nuclear ribonucleoprotein 200 kDa (SNRNP200) gene plays a key role in the maturation of pre-message RNA (pre-mRNA)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang T, Bai J, Zhang X, Zheng X, Lu N, Liang Z, Lin L, Chen Y. SNRNP200 Mutations Cause Autosomal Dominant Retinitis Pigmentosa. Front Med (Lausanne). 2021 Jan 21;7:588991. doi: 10.3389/fmed.2020.588991.

Pages