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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration

Authors:
Geng F, Ma J, Li X, Hu Z, Zhang R
Citation:
Int J Mol Sci. 2021;22(8):3945. doi:10.3390/ijms22083945
Epub:
Not Epub
Abstract:
Cardiac regenerative capacity varies widely among vertebrates. Zebrafish can robustly regenerate injured hearts and are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geng F, Ma J, Li X, Hu Z, Zhang R. Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration. Int J Mol Sci. 2021;22(8):3945. doi:10.3390/ijms22083945.

Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models

Authors:
Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439067
Epub:
Not Epub
Abstract:
The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N. Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439067 .

Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis

Authors:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N
Citation:
Proc Nat Acad Sci USA. 2021;118(15):e2021210118. doi:10.1073/pnas.2021210118
Epub:
Not Epub
Abstract:
Animal cytokinesis ends with the formation of a thin intercellular membrane bridge that connects the two newly formed sibling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N. Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis. Proc Nat Acad Sci USA. 2021;118(15):e2021210118. doi:10.1073/pnas.2021210118.

Zebrafish modeling mimics developmental phenotype of patients with RAPGEF1 mutation

Authors:
Li N, Zhou P, Yang M, Fang X, Krämer N, Mughal TA, Abbasi AA, Yang Y, Kaindl AM, Hu H
Citation:
Clin Genet. 2021 Apr 9. doi: 10.1111/cge.13965. Online ahead of print
Epub:
Yes
Abstract:
RAPGEF1 is a guanine nucleotide exchange factor responsible for transmitting extracellular signals to the Ras family of GTPase...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li N, Zhou P, Yang M, Fang X, Krämer N, Mughal TA, Abbasi AA, Yang Y, Kaindl AM, Hu H. Zebrafish modeling mimics developmental phenotype of patients with RAPGEF1 mutation. Clin Genet. 2021 Apr 9. doi: 10.1111/cge.13965. Online ahead of print.

Endothelial struts enable the generation of large lumenized blood vessels de novo

Authors:
Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D
Citation:
Nat Cell Biol. 2021;23(4):322-329. doi:10.1038/s41556-021-00664-3
Epub:
Not Epub
Abstract:
De novo blood vessel formation occurs through coalescence of endothelial cells (ECs) into a cord-like structure, followed by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021;23(4):322-329. doi:10.1038/s41556-021-00664-3.

BMP heterodimers signal via distinct type I receptor class functions

Authors:
Tajer B, Dutko JA, Little SC, Mullins MC
Citation:
Proc Nat Acad Sci USA. 2021;118(15):e2017952118. doi:10.1073/pnas.2017952118
Epub:
Not Epub
Abstract:
Heterodimeric TGF-β ligands outperform homodimers in a variety of developmental, cell culture, and therapeutic contexts;...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tajer B, Dutko JA, Little SC, Mullins MC. BMP heterodimers signal via distinct type I receptor class functions. Proc Nat Acad Sci USA. 2021;118(15):e2017952118. doi:10.1073/pnas.2017952118.

Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction

Authors:
Peruzzo R, Corrà S, Costa R, Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D, Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R, Szabò I
Citation:
Nat Comm. 2021;12(1):2103. doi:10.1038/s41467-021-22062-x
Epub:
Not Epub
Abstract:
Mitochondrial diseases impair oxidative phosphorylation and ATP production, while effective treatment is still lacking....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peruzzo R, Corrà S, Costa R, Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D, Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R, Szabò I. Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction. Nat Comm. 2021;12(1):2103. doi:10.1038/s41467-021-22062-x.

Human disease-associated extracellular matrix orthologs ECM3 and QBRICK regulate primary mesenchymal cell migration in sea urchin embryos

Authors:
Kiyozumi D, Yaguchi S, Yaguchi J, Yamazaki A, Sekiguchi K
Citation:
Exp Anim. 2021 Apr 6. doi: 10.1538/expanim.21-0001. Online ahead of print
Epub:
Yes
Abstract:
Sea urchin embryos have been one of model organisms to investigate cellular behaviors because of their simple cell composition...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Kiyozumi D, Yaguchi S, Yaguchi J, Yamazaki A, Sekiguchi K. Human disease-associated extracellular matrix orthologs ECM3 and QBRICK regulate primary mesenchymal cell migration in sea urchin embryos. Exp Anim. 2021 Apr 6. doi: 10.1538/expanim.21-0001. Online ahead of print.

Pluripotency factors determine gene expression repertoire at zygotic genome activation

Authors:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Ulianov SV, Timmer J, Onichtchouk D
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2020.02.16.949362
Epub:
Not Epub
Abstract:
Awakening of zygotic transcription in animal embryos relies on maternal pioneer transcription factors. The interplay of global...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Ulianov SV, Timmer J, Onichtchouk D. Pluripotency factors determine gene expression repertoire at zygotic genome activation. bioRxiv. 2021;[preprint] doi:10.1101/2020.02.16.949362.

Sobp modulates Six1 transcriptional activation and is required during craniofacial development

Authors:
Tavares ALP, Jourdeuil K, Neilson K, Majumdar H, Moody SA
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.05.438472
Epub:
Not Epub
Abstract:
Branchio-oto-renal syndrome (BOR) is a disorder characterized by hearing loss, craniofacial and/or renal defects. Mutations in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tavares ALP, Jourdeuil K, Neilson K, Majumdar H, Moody SA. Sobp modulates Six1 transcriptional activation and is required during craniofacial development. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.05.438472.

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