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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker
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Citation:
BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z Epub:
Not Epub Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker. BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z. |
Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus
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Citation:
Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16 Epub:
Not Epub Abstract:
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Johansen MD, Alcaraz M, Dedrick RM, Roquet-Banères F, Hamela C, Hatfull GF, Kremer L. Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus. Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16. |
Glypican 4 mediates Wnt transport between germ layers via signaling filopodia
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Citation:
J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082 Epub:
Not Epub Abstract:
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu B Rodriguez JJ Balaraju AK, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican 4 mediates Wnt transport between germ layers via signaling filopodia. J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082. |
The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway
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Citation:
Int J Mol Sci. 2021;22(19):10620. doi:10.3390/ijms221910620 Epub:
Not Epub Abstract:
NANOG is a key transcription factor required for maintaining pluripotency of embryonic stem cells. Elevated NANOG expression... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Sánchez-Sánchez AV, García-España A, Sánchez-Gómez P, Font-de-Mora J, Merino M, Mullor JL. The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway. Int J Mol Sci. 2021;22(19):10620. doi:10.3390/ijms221910620 . |
Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera
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Citation:
Nat Comm. 2021;12(1):5736. doi:10.1038/s41467-021-25466-x Epub:
Not Epub Abstract:
Despite the emerging importance of reactive electrophilic drugs, deconvolution of their principal targets remains difficult.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Poganik JR, Huang K-T, Parvez S, Zhao Y, Raja S, Long MJC, Aye Y. Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera. Nat Comm. 2021;12(1):5736. doi:10.1038/s41467-021-25466-x. |
Germ cells are not essential for sexual dimorphism of gonads in common carp, C. carpio L
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Citation:
Aquaculture. 2022;547:737501. doi:10.1016/j.aquaculture.2021.737501 Epub:
Not Epub Abstract:
Common carp is the fourth most cultivated fish species in the world. Sexually dimorphic growth of common carp makes its sex... Organism or Cell Type:
Cyprinus carpio (common carp) Citation Extract: Tao B, Liao X, Chen L, Li Y, Chen K, Jia S, Wu X, Ma W, Yunya Wu, Zhong W, Chen J, Song Y, Hu W. Germ cells are not essential for sexual dimorphism of gonads in common carp, C. carpio L. Aquaculture. 2022;547:737501. doi:10.1016/j.aquaculture.2021.737501. |
Grhl3 promotes retention of epidermal cells under endocytic stress to maintain epidermal architecture in zebrafish
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Citation:
PLoS Genet. 2021;17(9):e1009823. doi:10.1371/journal.pgen.1009823 Epub:
Not Epub Abstract:
Epithelia such as epidermis cover large surfaces and are crucial for survival. Maintenance of tissue homeostasis by balancing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Phatak M, Kulkarni S, Miles LB, Anjum N, Dworkin S, Sonawane M. Grhl3 promotes retention of epidermal cells under endocytic stress to maintain epidermal architecture in zebrafish. PLoS Genet. 2021;17(9):e1009823. doi:10.1371/journal.pgen.1009823. |
Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy
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Citation:
J Neuromuscul Dis. 2021 Sep 23. doi: 10.3233/JND-210696. Online ahead of print Epub:
Not Epub Abstract:
Recently, the Food and Drug Administration granted accelerated approvals for four exon skipping therapies -Eteplirsen,... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Novak JS, Spathis R, Dang UJ, Fiorillo AA, Hindupur R, Tully CB, Mázala DAG, Canessa E, Brown KJ, Partridge TA, Hathout Y, Nagaraju K. Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy. J Neuromuscul Dis. 2021 Sep 23. doi: 10.3233/JND-210696. Online ahead of print. |
Effects of Chronic, Maximal Phosphorodiamidate Morpholino Oligomer (PMO) Dosing on Muscle Function and Dystrophin Restoration in a Mouse Model of Duchenne Muscular Dystrophy
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Citation:
J Neuromuscul Dis. 2021 Sep 18. doi: 10.3233/JND-210701. Online ahead of print Epub:
Not Epub Abstract:
Background: Phosphorodiamidate morpholino oligomer (PMO)-mediated exon skipping is currently used in clinical development to... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Benny Klimek ME, Vila MC, Edwards K, Boehler J, Novak J, Zhang A, Van der Mulen JH, Tatum K, Quinn J, Fiorillo A, Burki U, Straub V, Lu QL, Hathout Y, van Den Anker J, Partridge TA, Morales M, Hoffman E, Nagaraju K. Effects of Chronic, Maximal Phosphorodiamidate Morpholino Oligomer (PMO) Dosing on Muscle Function and Dystrophin Restoration in a Mouse Model of Duchenne Muscular Dystrophy. J Neuromuscul Dis. 2021 Sep 18. doi: 10.3233/JND-210701. Online ahead of print. |
The cohesin stabilizer Sororin drives G2-M transition and spindle assembly in mammalian oocytes
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Citation:
Sci Adv. 2021;7(39):eabg9335 doi:10.1126/sciadv.abg9335 Epub:
Not Epub Abstract:
During the S phase of mitosis, Sororin is recruited by acetylated Smc3 and stabilizes sister chromatid cohesion by... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou C, Zhang X, Miao Y, Zhang Y, Li Y, Xiong B. The cohesin stabilizer Sororin drives G2-M transition and spindle assembly in mammalian oocytes. Sci Adv. 2021;7(39):eabg9335 doi:10.1126/sciadv.abg9335. |