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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.10.463758 Epub:
Not Epub Abstract:
Drastic epigenetic reprogramming is essential to convert terminally-differentiated gametes to totipotent embryos. However, it... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu X, Zhang H, Zhang B, Zhang Y, Wang Q, Shen W, Wu X, Lijia Li, Xia W, Nakamura Y, Liu B, Liu F, Takeda H, Meng A, Xie W. Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.10.463758 . |
Amoeboid-like neuronal migration ensures correct horizontal cell layer formation in the developing vertebrate retina
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.15.464510 Epub:
Not Epub Abstract:
As neurons are often born at positions different than where they ultimately function, neuronal migration is key to ensure... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Amini R, Schlüßler R, Möllmert S, Bhatnagar A, Guck J, Norden C. Amoeboid-like neuronal migration ensures correct horizontal cell layer formation in the developing vertebrate retina. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.15.464510. |
Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.25.465818 Epub:
Not Epub Abstract:
During neural development, progenitor cells generate different types of neurons in specific time windows. Despite the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jacobs CT, Kejriwal A, Kocha KM, Jin KY, Huang P. Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.25.465818. |
Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.18.464758 Epub:
Not Epub Abstract:
In the vertebrate retina, an interplay between retinal ganglion cells (RGCs), amacrine and bipolar cells establishes a synaptic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ahmed M, Kojima Y, Masai I. Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.18.464758. |
Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways
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Citation:
Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3 Epub:
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The transcriptional effector SMAD4 is a core component of the TGF-β family signaling pathways. However, its role in vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS. Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways. Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3. |
NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration
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Citation:
Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5 Epub:
Not Epub Abstract:
Fish species, such as zebrafish (Danio rerio), can regenerate their appendages after amputation through the formation of a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5. |
Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway
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Citation:
Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print Epub:
Not Epub Abstract:
In the context of obesity-induced adipose tissue inflammation, migration of macrophages and their polarization from... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S. Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway. Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print. |
Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability
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Citation:
J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039. Epub:
Not Epub Abstract:
Background: Allergy regroups numerous complex and various diseases classified as IgE-dependent or non-dependent... Delivery Method:
Vivo-Morpholino, peptide-linked Organism or Cell Type:
cell culture: B cells, myeloma cells; InEps mice Citation Extract: Marchalot A, Horiot C, Lambert J-M, Carrion C, Oblet C, Pollet J, Cogné M, Moreau J, Laffleur B, Delpy L. Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability. J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039.. |
Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish
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Citation:
Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883 Epub:
Not Epub Abstract:
The failure of amyloid beta (Aβ) clearance is a major cause of Alzheimer’s disease, and the brain lymphatic systems play a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jeong Y-M, Lee J-G, Cho H-J, Lee WS, Jeong J, Lee J-S. Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish. Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883. |
Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis
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Citation:
Front Cell Dev Biol. 2021 Oct 13;9:709923. doi: 10.3389/fcell.2021.709923 Epub:
Not Epub Abstract:
Vertebrate erythropoiesis involves nuclear and chromatin condensation at the early stages of terminal differentiation, which is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu S, Chen K, Xu T, Ma K, Gao L, Fu C, Zhang W, Jing C, Ren C, Deng M, Chen Y, Zhou Y, Pan W, Jia X. Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis. Front Cell Dev Biol. 2021 Oct 13;9:709923. doi: 10.3389/fcell.2021.709923. |