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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Furry is required for cell movements during gastrulation and functionally interacts with NDR1

Authors:
Cervino AS, Moretti B, Stuckenholz C, Grecco HE, Davidson LA, Cirio MC
Citation:
Sci Rep. 2021;11(1):6607. doi:10.1038/s41598-021-86153-x
Epub:
Not Epub
Abstract:
Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cervino AS, Moretti B, Stuckenholz C, Grecco HE, Davidson LA, Cirio MC. Furry is required for cell movements during gastrulation and functionally interacts with NDR1. Sci Rep. 2021;11(1):6607. doi:10.1038/s41598-021-86153-x.

Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression

Authors:
Zhang H-Y, Liang H-X, Wu S-H, Jiang H-Q, Wang Q, Yu Z-J
Citation:
Front Oncol. 2021;11:440. doi:10.3389/fonc.2021.622263
Epub:
Not Epub
Abstract:
Background: Hepatocellular carcinoma (HCC) is the most common primary liver tumor, and the main reason is the unclear...
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: HepG2
Citation Extract:
Zhang H-Y, Liang H-X, Wu S-H, Jiang H-Q, Wang Q, Yu Z-J. Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression. Front Oncol. 2021;11:440. doi:10.3389/fonc.2021.622263.

Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency

Authors:
Ravisankar S, Brooks KE, Murphy MJ, Redmayne N, Ryu J, Kinchen JM, Chavez SL, Hennebold JD
Citation:
Sci Rep. 2021;11(1):6506. doi:10.1038/s41598-021-85704-6
Epub:
Not Epub
Abstract:
Gonadotropin administration during infertility treatment stimulates the growth and development of multiple ovarian follicles,...
Delivery Method:
microinjection
Organism or Cell Type:
Macaca mulatta (rhesus macaque) oocyte
Citation Extract:
Ravisankar S, Brooks KE, Murphy MJ, Redmayne N, Ryu J, Kinchen JM, Chavez SL, Hennebold JD. Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency. Sci Rep. 2021;11(1):6506. doi:10.1038/s41598-021-85704-6.

NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis

Authors:
Ghaffari K, Pierce LX, Roufaeil M, Gibson I, Tae K, Sahoo S, Cantrell JT, Andersson O, Lau J, Sakaguchi TF
Citation:
PLoS Genet. 2021;17(3):e1009402. doi:10.1371/journal.pgen.1009402
Epub:
Not Epub
Abstract:
Impaired formation of the intrahepatic biliary network leads to cholestatic liver diseases, which are frequently associated...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghaffari K, Pierce LX, Roufaeil M, Gibson I, Tae K, Sahoo S, Cantrell JT, Andersson O, Lau J, Sakaguchi TF. NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis. PLoS Genet. 2021;17(3):e1009402. doi:10.1371/journal.pgen.1009402.

Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions

Authors:
Coxam B, Padberg Y, Maier K, Jung S, Bartels-Klein E, Szymborska A, Finotto L, Helker CSM, Stainier DYR, Schulte-Merker S, Gerhardt H
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.13.435246
Epub:
Not Epub
Abstract:
We report the discovery that flow and Svep1 are modulator of vessel anastomosis during developmental angiogenesis in zebrafish...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Coxam B, Padberg Y, Maier K, Jung S, Bartels-Klein E, Szymborska A, Finotto L, Helker CSM, Stainier DYR, Schulte-Merker S, Gerhardt H. Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.13.435246 .

Dram1 confers resistance to Salmonella infection

Authors:
Masud S, Zhang R, Prajsnar TK, Meijer AH
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.21.436194
Epub:
Not Epub
Abstract:
Dram1 is a stress and infection inducible autophagy modulator that functions downstream of transcription factors p53 and NFκB....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Masud S, Zhang R, Prajsnar TK, Meijer AH. Dram1 confers resistance to Salmonella infection. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.21.436194.

Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency

Authors:
Yu S-H, Wang T, Wiggins K, Louie RJ, Merino EF, Skinner C, Cassera MB, Meagher K, Goldberg P, Rismanchi N, Chen D, Lyons MJ, Flanagan-Steet H, Steet R
Citation:
Genet Med. 2021. doi:10.1038/s41436-021-01137-6
Epub:
Not Epub
Abstract:
Purpose: Variants in NUS1 are associated with a congenital disorder of glycosylation, developmental and epileptic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu S-H, Wang T, Wiggins K, Louie RJ, Merino EF, Skinner C, Cassera MB, Meagher K, Goldberg P, Rismanchi N, Chen D, Lyons MJ, Flanagan-Steet H, Steet R. Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency. Genet Med. 2021. doi:10.1038/s41436-021-01137-6.

Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep

Authors:
Han Z, Hao X, Zhou CJ, Wang J, Wen X, Wang XY, Zhang DJ, Liang CG
Citation:
Front Cell Dev Biol. 2021 Feb 25;9:609311. doi:10.3389/fcell.2021.609311. eCollection 2021
Epub:
Not Epub
Abstract:
As a major protein of the polyhedral coat of coated pits and vesicles, clathrin molecules have been shown to play a...
Delivery Method:
microinjection
Organism or Cell Type:
Ovis aries (sheep oocytes)
Citation Extract:
Han Z, Hao X, Zhou CJ, Wang J, Wen X, Wang XY, Zhang DJ, Liang CG. Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep. Front Cell Dev Biol. 2021 Feb 25;9:609311. doi:10.3389/fcell.2021.609311. eCollection 2021.

kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation

Authors:
Subramaniam Y, Murthy D, Raja DA, Ramkumar A, Sivasubbu S, McEwan DG, Gokhale RS, Natarajan VT
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434917
Epub:
Not Epub
Abstract:
Anterograde melanosome transport is essential for adaptive skin tanning response. However, the molecular components involved,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramaniam Y, Murthy D, Raja DA, Ramkumar A, Sivasubbu S, McEwan DG, Gokhale RS, Natarajan VT. kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434917.

Oligodendrocyte Precursor Cells Sculpt the Visual System by Regulating Axonal Remodeling

Authors:
Xiao Y, Hoodless LJ, Petrucco L, Portugues R, Czopka T
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434829
Epub:
Not Epub
Abstract:
Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting additional roles of this cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiao Y, Hoodless LJ, Petrucco L, Portugues R, Czopka T. Oligodendrocyte Precursor Cells Sculpt the Visual System by Regulating Axonal Remodeling. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434829.

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