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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

A precise regulation of presenilin expression is required for the sea urchin early development

Authors:
Bronchain O, Philippe-Caraty L, Anquetil V, Ciapa B
Citation:
J Cell Sci. 2021;jcs.258382. doi:10.1242/jcs.258382
Epub:
Not Epub
Abstract:
Presenilins or PSENs homologues are widely expressed across eukaryotes. Two PSEN are expressed in humans where they play a...
Organism or Cell Type:
sea urchin
Citation Extract:
Bronchain O, Philippe-Caraty L, Anquetil V, Ciapa B. A precise regulation of presenilin expression is required for the sea urchin early development. J Cell Sci. 2021;jcs.258382. doi:10.1242/jcs.258382.

Three-dimensional folding dynamics of the Xenopus tropicalis genome

Authors:
Niu L, Shen W, Shi Z, Tan Y, He N, Wan J, Sun J, Zhang Y, Huang Y, Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Li L, Hou C
Citation:
Nat Genet. 2021;[Epub ahead of print] doi:10.1038/s41588-021-00878-z
Epub:
Yes
Abstract:
Animal interphase chromosomes are organized into topologically associating domains (TADs). How TADs are formed is not fully...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Niu L, Shen W, Shi Z, Tan Y, He N, Wan J, Sun J, Zhang Y, Huang Y, Wang W, Fang C, Li J, Zheng P, Cheung E, Chen Y, Li L, Hou C. Three-dimensional folding dynamics of the Xenopus tropicalis genome. Nat Genet. 2021;[Epub ahead of print] doi:10.1038/s41588-021-00878-z.

Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing in vitro and in vivo zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells

Authors:
Kundu J, Das U, Bose C, Bhadra J, Sinha S
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.04.447039
Epub:
Not Epub
Abstract:
Phosphorodiamidate Morpholino Oligonucleotides (PMOs)-based antisense reagents cannot enter inside cells by itself without the...
Delivery Method:
guanidinium-morpholino and Morpholino chimeras
Organism or Cell Type:
cell culture: Shh-Light 2, MCF7, PC-3, MDA MB-231, Shh-N; zebrafish
Citation Extract:
Kundu J, Das U, Bose C, Bhadra J, Sinha S. Self-transfecting GMO-PMO and PMO-GMO chimeras enable gene silencing in vitro and in vivo zebrafish model and NANOG Inhibition Induce the Apoptosis in Breast and Prostate Cancer Cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.04.447039.

Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code

Authors:
Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/292458
Epub:
Not Epub
Abstract:
The specific recognition of splice signals at or near exon-intron junctions is not explained by their weak conservation and...
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G. Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code. bioRxiv. 2021;[preprint] doi:10.1101/292458 .

Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure

Authors:
Christodoulou N, Skourides PA
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.01.446407
Epub:
Not Epub
Abstract:
Neural tube closure (NTC) is a fundamental process during vertebrate embryonic development and is indispensable for the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Christodoulou N, Skourides PA. Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.01.446407 .

[Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]

Authors:
Takada-Takatori Y
Citation:
Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6
Epub:
Not Epub
Abstract:
Donepezil, the most widely used drug for the treatment of Alzheimer's disease (AD), is an acetylcholinesterase (AChE)...
Organism or Cell Type:
cell culture: primary fetal rat cortical neurons
Citation Extract:
Takada-Takatori Y. [Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]. Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6.

Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos

Authors:
Orbán L, Saju JM, Tzung KW, Liew WC
Citation:
In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5
Epub:
Not Epub
Abstract:
The regulation of reproduction in zebrafish, the prime model of fish research, is not fully understood. An efficient tool to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Orbán L, Saju JM, Tzung KW, Liew WC. Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos. In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5.

Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage

Authors:
Houseright RA, Miskolci V, Mulvaney O, Bortnov V, Mosher DF, Rindy J, Bennin DA, Huttenlocher A
Citation:
J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054
Epub:
Not Epub
Abstract:
Neutrophil recruitment to tissue damage is essential for host defense but can also impede tissue repair. The cues that...
Organism or Cell Type:
zebrafish
Citation Extract:
Houseright RA, Miskolci V, Mulvaney O, Bortnov V, Mosher DF, Rindy J, Bennin DA, Huttenlocher A. Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage. J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054.

A Novel BLOC1S5-Related HPS-11 Patient and Zebrafish with bloc1s5 Disruption

Authors:
Zhong Z, Wu Z, Zhang J, Chen J
Citation:
Pigment Cell Melanoma Res. 2021 May 31. doi: 10.1111/pcmr.12995. Online ahead of print
Epub:
Yes
Abstract:
HPS (Hermansky-Pudlak Syndrome) cases present with a variable degree of OCA and bleeding tendency. HPS is categorized into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Z, Wu Z, Zhang J, Chen J. A Novel BLOC1S5-Related HPS-11 Patient and Zebrafish with bloc1s5 Disruption. Pigment Cell Melanoma Res. 2021 May 31. doi: 10.1111/pcmr.12995. Online ahead of print.

Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish

Authors:
Gong J, Qian P, Hu Y, Guo C, Wei G, Wang C, Cai C, Wang H, Liu D
Citation:
Front Cell Dev Biol. 2021 May 11;9:663995. doi: 10.3389/fcell.2021.663995. eCollection 2021
Epub:
Not Epub
Abstract:
Hereditary hearing loss caused by defective hair cells is one of the most common congenital diseases, whose nosogenesis is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong J, Qian P, Hu Y, Guo C, Wei G, Wang C, Cai C, Wang H, Liu D. Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish. Front Cell Dev Biol. 2021 May 11;9:663995. doi: 10.3389/fcell.2021.663995. eCollection 2021.

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