You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos

Authors:
Ghilardi A, Diana A, Bacchetta R, Santo N, Ascagni M, Prosperi L, Del Giacco L
Citation:
Int J Mol Sci. 2021;22(12):6497. doi:10.3390/ijms22126497
Epub:
Not Epub
Abstract:
The last decade has witnessed the identification of several families affected by hereditary non-syndromic hearing loss (NSHL)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghilardi A, Diana A, Bacchetta R, Santo N, Ascagni M, Prosperi L, Del Giacco L. Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos. Int J Mol Sci. 2021;22(12):6497. doi:10.3390/ijms22126497.

Hif1α is required for Wnt regulated gene expression during Xenopus tropicalis tail regeneration

Authors:
Patel JH, Schattinger PA, Takayoshi EE, Wills AE
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444777
Epub:
Not Epub
Abstract:
Regeneration of complex tissues is initiated by an injury-induced stress response, eventually leading to activation of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Patel JH, Schattinger PA, Takayoshi EE, Wills AE. Hif1α is required for Wnt regulated gene expression during Xenopus tropicalis tail regeneration. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444777.

Semaphorin3f as an intrinsic regulator of chamber-specific heart development

Authors:
Halabi R, Cechmanek PB, Hehr CL, McFarlane S
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444704
Epub:
Not Epub
Abstract:
During development a pool of precursors form a heart with atrial and ventricular chambers that exhibit distinct transcriptional...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Halabi R, Cechmanek PB, Hehr CL, McFarlane S. Semaphorin3f as an intrinsic regulator of chamber-specific heart development. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444704.

12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes

Authors:
Kulkarni A, Pineros AR, Walsh MA, Casimiro I, Ibrahim S, Hernandez-Perez M, Orr KS, Glenn L, Nadler JL, Morris MA, Tersey SA, Mirmira RG, Anderson RM
Citation:
JCI Insight. 2021 Jun 15:147812. doi:10.1172/jci.insight.147812. Online ahead of print
Epub:
Yes
Abstract:
Macrophages and related myeloid cells are innate immune cells that participate in the early islet inflammation of type 1...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kulkarni A, Pineros AR, Walsh MA, Casimiro I, Ibrahim S, Hernandez-Perez M, Orr KS, Glenn L, Nadler JL, Morris MA, Tersey SA, Mirmira RG, Anderson RM. 12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes. JCI Insight. 2021 Jun 15:147812. doi:10.1172/jci.insight.147812. Online ahead of print.

Zebrafish Minichromosome Maintenance Protein 5 Gene Regulates the Development and Migration of Facial Motor Neurons via Fibroblast Growth Factor Signaling

Authors:
Wu Y, Huang S, Zhao H, Cao K, Gan J, Yang C, Xu Z, Li S, Su B
Citation:
Dev Neurosci. 2021;[Epub} doi:10.1159/000514852
Epub:
Not Epub
Abstract:
Minichromosome maintenance protein 5 (MCM5), a member of the microchromosomal maintenance protein family, plays an important...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y, Huang S, Zhao H, Cao K, Gan J, Yang C, Xu Z, Li S, Su B. Zebrafish Minichromosome Maintenance Protein 5 Gene Regulates the Development and Migration of Facial Motor Neurons via Fibroblast Growth Factor Signaling. Dev Neurosci. 2021;[Epub} doi:10.1159/000514852.

A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle

Authors:
Yang Y, Wang H, He J, Shi W, Jiang Z, Gao L, Jiang Y, Ni R, Yang Q, Luo L
Citation:
Proc Nat Acad Sci USA. 2021;118(25):e2025793118. doi:10.1073/pnas.2025793118
Epub:
Not Epub
Abstract:
A progenitor cell could generate a certain type or multiple types of descendant cells during embryonic development. To make all...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Y, Wang H, He J, Shi W, Jiang Z, Gao L, Jiang Y, Ni R, Yang Q, Luo L. A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle. Proc Nat Acad Sci USA. 2021;118(25):e2025793118. doi:10.1073/pnas.2025793118 .

Echinoderm Microtubule Associated Protein Like 1 Is Indispensable for Oocyte Spindle Assembly and Meiotic Progression in Mice

Authors:
Yin H, Zhang T, Wang H, Hu X, Hou X, Fang X, Yin Y, Li H, Shi L, Su YQ
Citation:
Front Cell Dev Biol. 2021 May 28;9:687522. doi:10.3389/fcell.2021.687522. eCollection 2021
Epub:
Not Epub
Abstract:
Completion of the first meiosis is an essential prerequisite for producing a functionally normal egg for fertilization and...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Yin H, Zhang T, Wang H, Hu X, Hou X, Fang X, Yin Y, Li H, Shi L, Su YQ. Echinoderm Microtubule Associated Protein Like 1 Is Indispensable for Oocyte Spindle Assembly and Meiotic Progression in Mice. Front Cell Dev Biol. 2021 May 28;9:687522. doi:10.3389/fcell.2021.687522. eCollection 2021.

Chapter Six - Emerging RNA Suppression Technologies to Protect Citrus Trees From Citrus Greening Disease Bacteria

Authors:
Hunter WB, Sinisterra-Hunter SH
Citation:
Adv In Insect Physiol. 2018;55:163-197. doi:10.1016/bs.aiip.2018.08.001
Epub:
Not Epub
Abstract:
Research on the development of RNA-suppressing technologies, which include RNA interference, (RNAi), and the application of RNA...
Delivery Method:
peptide-linked
Organism or Cell Type:
Candidatus Liberibacter asiaticus
Citation Extract:
Hunter WB, Sinisterra-Hunter SH. Chapter Six - Emerging RNA Suppression Technologies to Protect Citrus Trees From Citrus Greening Disease Bacteria. Adv In Insect Physiol. 2018;55:163-197. doi:10.1016/bs.aiip.2018.08.001.

Neutral Surfactant Enhanced Exon-skipping of Morpholino Oligonucleotides in vitro and in mdx Mice

Authors:
Wu B, Drains M, Lu P, Lu Q, Wang M
Citation:
J Nanomed Nanotechnol. 2020;11(6):553. doi:10.35248/2157-7439.20.11.553
Epub:
Not Epub
Abstract:
Antisense oligomers induced exon-skipping has been promising therapy for Duchenne muscular dystrophy in preclinical and...
Delivery Method:
Endo-Porter (culture), local injection (mice)
Organism or Cell Type:
cell culture: C2C12E50 myoblasts and C2C12E23 differentiated cells expressing human dystrophin exon 50 sequence (hDyE50), mouse dystrophin exon 23 sequence (mDyE23) in the GFP coding sequence, respectively; mdx mice
Citation Extract:
Wu B, Drains M, Lu P, Lu Q, Wang M. Neutral Surfactant Enhanced Exon-skipping of Morpholino Oligonucleotides in vitro and in mdx Mice. J Nanomed Nanotechnol. 2020;11(6):553. doi:10.35248/2157-7439.20.11.553.

Sobp modulates Six1 transcriptional activation and is required during craniofacial development

Authors:
Tavares ALP, Jourdeuil K, Neilson KM, Majumdar HD, Moody SA
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.05.438472
Epub:
Not Epub
Abstract:
Single nucleotide mutations in SIX1 are causative in some individuals diagnosed with branchio-otic/branchio-oto-renal (BOR)...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tavares ALP, Jourdeuil K, Neilson KM, Majumdar HD, Moody SA. Sobp modulates Six1 transcriptional activation and is required during craniofacial development. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.05.438472 .

Pages