You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Novel zebrafish mutants reveal new roles for Apolipoprotein B during embryonic development and pathological conditions

Authors:
Templehof H, Moshe N, Avraham-Davidi I, Yaniv K
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.01.437990
Epub:
Not Epub
Abstract:
Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs and LDLs and is essential for their assembly. Defects in...
Link:
https://www.biorxiv.org/content/10.1101/2021.04.01.437990v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Templehof H, Moshe N, Avraham-Davidi I, Yaniv K. Novel zebrafish mutants reveal new roles for Apolipoprotein B during embryonic development and pathological conditions. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.01.437990.

The Kunitz-type serine protease inhibitor Spint2 is required for cellular cohesion, coordinated cell migration and cell survival during zebrafish hatching gland development

Authors:
Hatzold J, Wessendorf H, Pogoda H-M, Bloch W, Hammerschmidt M
Citation:
Dev Biol. 2021;[Epub ahead of print] doi: 10.1016/j.ydbio.2021.03.017
Epub:
Yes
Abstract:
We have previously shown that the Kunitz-type serine protease inhibitor Spint1a, also named Hai1a, is required in the zebrafish...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160621000774
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hatzold J, Wessendorf H, Pogoda H-M, Bloch W, Hammerschmidt M. The Kunitz-type serine protease inhibitor Spint2 is required for cellular cohesion, coordinated cell migration and cell survival during zebrafish hatching gland development. Dev Biol. 2021;[Epub ahead of print] doi: 10.1016/j.ydbio.2021.03.017.

Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder

Authors:
Latypova X, Vincent M, Mollé A, Adebambo OA, Fourgeux C, Khan TN, Caro A, Rosello M, Orellana C, Niyazov D, Lederer D, Deprez M, Capri Y, Kannu P, Tabet AC, Levy J, Aten E, den Hollander N, Splitt M, Walia J, Immken LL, Stankiewicz P, McWalter K, Suchy S, Louie RJ, Bell S, Stevenson RE, Rousseau J, Willem C, Retiere C, Yang X-J, Campeau PM, Martinez F, Rosenfeld JA, Le Caignec C, Küry S, Mercier S, Moradkhani K, Conrad S, Besnard T, Cogné B, Katsanis N, Bézieau S, Poschmann J, Davis EE, Isidor B
Citation:
Am J Hum Genet. 2021;108(5):929-41. doi:10.1016/j.ajhg.2021.03.017
Epub:
Not Epub
Abstract:
Proteins involved in transcriptional regulation harbor a demonstrated enrichment of mutations in neurodevelopmental disorders....
Link:
https://www.cell.com/ajhg/fulltext/S0002-9297(21)00101-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Latypova X, Vincent M, Mollé A, Adebambo OA, Fourgeux C, Khan TN, Caro A, Rosello M, Orellana C, Niyazov D, Lederer D, Deprez M, Capri Y, Kannu P, Tabet AC, Levy J, Aten E, den Hollander N, Splitt M, Walia J, Immken LL, Stankiewicz P, McWalter K, Suchy S, Louie RJ, Bell S, Stevenson RE, Rousseau J, Willem C, Retiere C, Yang X-J, Campeau PM, Martinez F, Rosenfeld JA, Le Caignec C, Küry S, Mercier S, Moradkhani K, Conrad S, Besnard T, Cogné B, Katsanis N, Bézieau S, Poschmann J, Davis EE, Isidor B. Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder. Am J Hum Genet. 2021;108(5):929-41. doi:10.1016/j.ajhg.2021.03.017.

Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula

Authors:
Nagel M, Barua D, Damm EW, Kashef J, Hofmann R, Ershov A, Cecilia A, Moosmann J, Baumbach T, Winklbauer R
Citation:
Development. 2021 Mar 29;148(18):dev198960. doi: 10.1242/dev.198960
Epub:
Not Epub
Abstract:
During Xenopus gastrulation, leading edge mesendoderm (LEM) advances animally as a wedge-shaped cell mass over the vegetally...
Link:
https://dev.biologists.org/content/148/18/dev198960
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nagel M, Barua D, Damm EW, Kashef J, Hofmann R, Ershov A, Cecilia A, Moosmann J, Baumbach T, Winklbauer R. Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula. Development. 2021 Mar 29;148(18):dev198960. doi: 10.1242/dev.198960.

Loss of splicing factor IK impairs normal skeletal muscle development

Authors:
In Ka H, Seo H, Choi YKim J, Cho M, Choi SY, Park S, Han S, An J, Chung HS, Yang Y, Kim MJ
Citation:
BMC Biol. 2021 Apr 1;19(1):44. doi:10.1186/s12915-021-00980-y
Epub:
Not Epub
Abstract:
Background: IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the...
Link:
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-021-00980-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
In Ka H, Seo H, Choi YKim J, Cho M, Choi SY, Park S, Han S, An J, Chung HS, Yang Y, Kim MJ. Loss of splicing factor IK impairs normal skeletal muscle development. BMC Biol. 2021 Apr 1;19(1):44. doi:10.1186/s12915-021-00980-y.

A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish

Authors:
Xia J, Kang Z, Xue Y, Ding Y, Gao S, Zhang Y, Lv P, Wang X, Ma D, Wang L, Han J-DJ, Liu F
Citation:
Proc Nat Acad Sci USA. 2021;118(14):e2015748118. doi:10.1073/pnas.2015748118
Epub:
Not Epub
Abstract:
During vertebrate embryogenesis, fetal hematopoietic stem and progenitor cells (HSPCs) exhibit expansion and differentiation...
Link:
https://www.pnas.org/content/118/14/e2015748118
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia J, Kang Z, Xue Y, Ding Y, Gao S, Zhang Y, Lv P, Wang X, Ma D, Wang L, Han J-DJ, Liu F. A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish. Proc Nat Acad Sci USA. 2021;118(14):e2015748118. doi:10.1073/pnas.2015748118.

Role of epigenetic m6A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR‐AKT signaling

Authors:
Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK
Citation:
FASEB J. 2021;[Epub] doi:10.1096/fj.202000516RR
Epub:
Yes
Abstract:
N6‐methyladenosine (m6A) methylation is the most prevalent RNA modification, and it emerges as an important regulatory...
Link:
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202000516RR
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK. Role of epigenetic m6A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR‐AKT signaling. FASEB J. 2021;[Epub] doi:10.1096/fj.202000516RR.

A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia

Authors:
Park EA, Kim J, Shin MY, Park S-J
Citation:
Parasit Vectors. 2021;14:182. doi:10.1186/s13071-021-04687-5
Epub:
Not Epub
Abstract:
Background: Polo-like kinases (PLKs) are conserved serine/threonine kinases that regulate the cell cycle. To date, the role of...
Link:
https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-021-04687-5
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Park EA, Kim J, Shin MY, Park S-J. A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia. Parasit Vectors. 2021;14:182. doi:10.1186/s13071-021-04687-5.

Rapid and Unamplified Identification of COVID-19 with Morpholino-Modified Graphene Field-Effect Transistor Nanosensor

Authors:
Li J, Wu D, Yu Y, Li T, Li K, Xiao M-M, Li Y, Zhang Z-Y, Zhang G-J
Citation:
Biosens Bioelectron. 2021;[Epub] doi:10.1016/j.bios.2021.113206
Epub:
Yes
Abstract:
SARS-CoV-2 RNA is identified as a pivotal player to bolster energizing zones of COVID-19 detection. Herein, we develop a rapid...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0956566321002438
Citation Extract:
Li J, Wu D, Yu Y, Li T, Li K, Xiao M-M, Li Y, Zhang Z-Y, Zhang G-J. Rapid and Unamplified Identification of COVID-19 with Morpholino-Modified Graphene Field-Effect Transistor Nanosensor. Biosens Bioelectron. 2021;[Epub] doi:10.1016/j.bios.2021.113206.

NOX5 is Expressed Aberrantly but Not a Critical Pathogenetic Gene in Hirschsprung Disease

Authors:
Wang J, Xiao J, Meng X, Chu X, Zhuansun DD, Xiong B, Feng J
Citation:
BMC Pediatr. 2021;15:123 doi:10.1186/s12887-021-02611-5
Epub:
Not Epub
Abstract:
Background: Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of intramural ganglion cells in...
Link:
https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-021-02611-5
Citation Extract:
Wang J, Xiao J, Meng X, Chu X, Zhuansun DD, Xiong B, Feng J. NOX5 is Expressed Aberrantly but Not a Critical Pathogenetic Gene in Hirschsprung Disease. BMC Pediatr. 2021;15:123 doi:10.1186/s12887-021-02611-5.

Pages