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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish

Authors:
Mo C, Li W, Jia K, Liu W, Yi M
Citation:
Int J Mol Sci. 2021;22(21):11962. doi:10.3390/ijms222111962
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) play important roles in post−transcriptional repression in nearly every biological process including germ...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mo C, Li W, Jia K, Liu W, Yi M. Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish. Int J Mol Sci. 2021;22(21):11962. doi:10.3390/ijms222111962.

Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes

Authors:
Swartz SZ, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake AH, Cheeseman IM
Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.10.022
Epub:
Yes
Abstract:
The organismal body axes that are formed during embryogenesis are intimately linked to intrinsic asymmetries established at the...
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Swartz SZ, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake AH, Cheeseman IM. Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.10.022.

Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin

Authors:
Honglin L, Yongde Z, Yanfei D, Lequn L, Zhaoan S, Yanling Y, Yong L, Xiaohan C, Pengfei F
Citation:
Front Cell Dev Biol. 2021;9:2716. doi:10.3389/fcell.2021.728821
Epub:
Not Epub
Abstract:
Precise regulation of angiogenesis is required for organ development, wound repair, and tumor progression. Here, we identified...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Honglin L, Yongde Z, Yanfei D, Lequn L, Zhaoan S, Yanling Y, Yong L, Xiaohan C, Pengfei F. Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin. Front Cell Dev Biol. 2021;9:2716. doi:10.3389/fcell.2021.728821.

Clonal gametogenesis is triggered by intrinsic stimuli in the hybrid's germ cells but is dependent on sex differentiation

Authors:
Tichopád T, Franěk R, Doležálková-Kaštánková M, Dedukh D, Marta A, Halačka K, Steinbach C, Janko K, Pšenička M
Citation:
Biol Reprod. 2022 Aug 9;107(2):446-457. doi: 10.1093/biolre/ioac074. PMID: 35416937
Epub:
Not Epub
Abstract:
Interspecific hybridization may trigger the transition from sexual reproduction to asexuality, but mechanistic reasons for such...
Delivery Method:
microinjection
Organism or Cell Type:
Cobitis taenia, Cobitis elongatoides (spined loach)
Citation Extract:
Tichopád T, Franěk R, Doležálková-Kaštánková M, Dedukh D, Marta A, Halačka K, Steinbach C, Janko K, Pšenička M. Clonal gametogenesis is triggered by intrinsic stimuli in the hybrid's germ cells but is dependent on sex differentiation. Biol Reprod. 2022 Aug 9;107(2):446-457. doi: 10.1093/biolre/ioac074. PMID: 35416937.

Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina

Authors:
Amini R, Bhatnagar A, Schlüßler R, Möllmert S, Guck J, Norden C
Citation:
Elife. 2022 May 31;11:e76408. doi: 10.7554/eLife.76408. PMID: 35639083; PMCID: PMC9208757
Epub:
Not Epub
Abstract:
Migration of cells in the developing brain is integral for the establishment of neural circuits and function of the central...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amini R, Bhatnagar A, Schlüßler R, Möllmert S, Guck J, Norden C. Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina. Elife. 2022 May 31;11:e76408. doi: 10.7554/eLife.76408. PMID: 35639083; PMCID: PMC9208757.

Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways

Authors:
Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS
Citation:
Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3
Epub:
Not Epub
Abstract:
The transcriptional effector SMAD4 is a core component of the TGF-β family signaling pathways. However, its role in vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS. Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways. Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3.

NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration

Authors:
Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F
Citation:
Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5
Epub:
Not Epub
Abstract:
Fish species, such as zebrafish (Danio rerio), can regenerate their appendages after amputation through the formation of a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5.

Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway

Authors:
Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S
Citation:
Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print
Epub:
Not Epub
Abstract:
In the context of obesity-induced adipose tissue inflammation, migration of macrophages and their polarization from...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S. Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway. Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print.

Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability

Authors:
Marchalot A, Horiot C, Lambert J-M, Carrion C, Oblet C, Pollet J, Cogné M, Moreau J, Laffleur B, Delpy L
Citation:
J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039.
Epub:
Not Epub
Abstract:
Background: Allergy regroups numerous complex and various diseases classified as IgE-dependent or non-dependent...
Delivery Method:
Vivo-Morpholino, peptide-linked
Organism or Cell Type:
cell culture: B cells, myeloma cells; InEps mice
Citation Extract:
Marchalot A, Horiot C, Lambert J-M, Carrion C, Oblet C, Pollet J, Cogné M, Moreau J, Laffleur B, Delpy L. Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability. J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039..

Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish

Authors:
Jeong Y-M, Lee J-G, Cho H-J, Lee WS, Jeong J, Lee J-S
Citation:
Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883
Epub:
Not Epub
Abstract:
The failure of amyloid beta (Aβ) clearance is a major cause of Alzheimer’s disease, and the brain lymphatic systems play a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jeong Y-M, Lee J-G, Cho H-J, Lee WS, Jeong J, Lee J-S. Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish. Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883.

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