You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

The Proapoptotic Gene Bad Regulates Brain Development via P53-Mediated Stress Signals in Zebrafish

Authors:
Hung J-C, Wu J-L, Li H-C, Chiu H-W, Hong J-R
Citation:
Cells. 2021;10(11):2820. doi:10.3390/cells10112820
Epub:
Not Epub
Abstract:
Studies have shown that the BH3-only domain Bad regulates brain development via the control of programmed cell death (PCD), but...
Link:
https://www.mdpi.com/2073-4409/10/11/2820
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung J-C, Wu J-L, Li H-C, Chiu H-W, Hong J-R. The Proapoptotic Gene Bad Regulates Brain Development via P53-Mediated Stress Signals in Zebrafish. Cells. 2021;10(11):2820. doi:10.3390/cells10112820.

Genetic landscape of T cells identifies synthetic lethality for T-ALL

Authors:
O’Meara CP, Guerri L, Lawir D-F, Mateos F, Iconomou M, Iwanami N, Soza-Ried C, Sikora K, Siamishi I, Giorgetti O, Peter S, Schorpp M, Boehm T
Citation:
Comm Biol. 2021;4(1):1201. doi:10.1038/s42003-021-02694-x
Epub:
Not Epub
Abstract:
To capture the global gene network regulating the differentiation of immature T cells in an unbiased manner, large-scale...
Link:
https://www.nature.com/articles/s42003-021-02694-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
O’Meara CP, Guerri L, Lawir D-F, Mateos F, Iconomou M, Iwanami N, Soza-Ried C, Sikora K, Siamishi I, Giorgetti O, Peter S, Schorpp M, Boehm T. Genetic landscape of T cells identifies synthetic lethality for T-ALL. Comm Biol. 2021;4(1):1201. doi:10.1038/s42003-021-02694-x.

Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis

Authors:
Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg C-P, Galande S
Citation:
Nat Commun. 2021;12(1):6094. doi:10.1038/s41467-021-26234-7
Epub:
Not Epub
Abstract:
Zygotic genome activation (ZGA) initiates regionalized transcription underlying distinct cellular identities. ZGA is dependent...
Link:
https://www.nature.com/articles/s41467-021-26234-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg C-P, Galande S. Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nat Commun. 2021;12(1):6094. doi:10.1038/s41467-021-26234-7.

NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice

Authors:
Wang H, Zhu S, Wu X, Liu Y, Ge J, Wang Q, Gu L
Citation:
Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print
Epub:
Not Epub
Abstract:
Maternal obesity is associated with multiple adverse reproductive outcomes, whereas the underlying molecular mechanisms are...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/acel.13496
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Wang H, Zhu S, Wu X, Liu Y, Ge J, Wang Q, Gu L. NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice. Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print.

Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish

Authors:
Umair M, Farooq Khan M, Aldrees M, Nashabat M, Alhamoudi KM, Bilal M, Alyafee Y, Al Tuwaijri A, Aldarwish M, Al-Rumayyan A, Alkhalaf H, Wadaan MAM, Alfadhel M
Citation:
Front Cell Dev Biol. 2021 Oct 1;9:736960. doi: 10.3389/fcell.2021.736960. eCollection 2021
Epub:
Not Epub
Abstract:
Von Willebrand A domain-containing protein 8 (VWA8), also named KIAA0564, is a poorly characterized, mitochondrial matrix-...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2021.736960/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Umair M, Farooq Khan M, Aldrees M, Nashabat M, Alhamoudi KM, Bilal M, Alyafee Y, Al Tuwaijri A, Aldarwish M, Al-Rumayyan A, Alkhalaf H, Wadaan MAM, Alfadhel M. Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish. Front Cell Dev Biol. 2021 Oct 1;9:736960. doi: 10.3389/fcell.2021.736960. eCollection 2021.

Nucleolin loss of function leads to aberrant Fibroblast Growth Factor signaling and craniofacial anomalies

Authors:
Dash S, Trainor PA
Citation:
Development. 2022 Jun 15;149(12):dev200349. doi: 10.1242/dev.200349. Epub 2022 Jun 28. PMID: 35762670; PMCID: PMC9270975
Epub:
Not Epub
Abstract:
Ribosomal RNA (rRNA) transcription and ribosome biogenesis are global processes required for growth and proliferation of all...
Link:
https://journals.biologists.com/dev/article/149/12/dev200349/275828/Nucleolin-loss-of-function-leads-to-aberrant
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dash S, Trainor PA. Nucleolin loss of function leads to aberrant Fibroblast Growth Factor signaling and craniofacial anomalies. Development. 2022 Jun 15;149(12):dev200349. doi: 10.1242/dev.200349. Epub 2022 Jun 28. PMID: 35762670; PMCID: PMC9270975.

The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling

Authors:
Ding Y, Li Y, Zhao Z, Cliff Zhang Q, Liu F
Citation:
Elife. 2021 Oct 26;10:e72557. doi: 10.7554/eLife.72557. PMID: 34698638; PMCID: PMC8594921
Epub:
Not Epub
Abstract:
Although thrombosis has been extensively studied using various animal models, our understanding of the underlying mechanism...
Link:
https://elifesciences.org/articles/72557
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ding Y, Li Y, Zhao Z, Cliff Zhang Q, Liu F. The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling. Elife. 2021 Oct 26;10:e72557. doi: 10.7554/eLife.72557. PMID: 34698638; PMCID: PMC8594921.

Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development

Authors:
Lee H, Lee NY, Kim Y, Choi H-S, Ismail T, Ryu H-Y, Cho D-H, Ryoo ZY, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S
Citation:
Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636
Epub:
Not Epub
Abstract:
Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have...
Link:
https://www.mdpi.com/2076-3921/10/10/1636
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lee H, Lee NY, Kim Y, Choi H-S, Ismail T, Ryu H-Y, Cho D-H, Ryoo ZY, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development. Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636.

Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish

Authors:
Chiang K-Y, Li Y-W, Li Y-H, Huang S-J, Wu C-L, Gong H-Y, Wu J-L
Citation:
Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217
Epub:
Not Epub
Abstract:
Compensatory hepatocyte proliferation and other liver regenerative processes are activated to sustain normal physiological...
Link:
https://www.mdpi.com/1422-0067/22/20/11217
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang K-Y, Li Y-W, Li Y-H, Huang S-J, Wu C-L, Gong H-Y, Wu J-L. Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish. Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217.

A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss

Authors:
Ullah F, Rauf W, Khan K, Khan S, Bell KM, de Oliveira VC, Tariq M, Bakhshalizadeh S, Touraine P, Katsanis N, Sinclair A, He S, Tucker EJ, Baig SM, Davis EE
Citation:
Hum Genet. 2021 Oct 13. doi: 10.1007/s00439-021-02380-2. Online ahead of print
Epub:
Yes
Abstract:
Mitochondrial disorders are collectively common, genetically heterogeneous disorders in both pediatric and adult populations....
Link:
https://link.springer.com/article/10.1007/s00439-021-02380-2
Organism or Cell Type:
zebrafish
Citation Extract:
Ullah F, Rauf W, Khan K, Khan S, Bell KM, de Oliveira VC, Tariq M, Bakhshalizadeh S, Touraine P, Katsanis N, Sinclair A, He S, Tucker EJ, Baig SM, Davis EE. A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss. Hum Genet. 2021 Oct 13. doi: 10.1007/s00439-021-02380-2. Online ahead of print.

Pages