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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Mvda is required for zebrafish early development

Authors:
Wong W, Huang Y, Wu Z, Kong Y, Luan J, Zhang Q, Pan J, Yan K, Zhang Z
Citation:
Biol Res. 2021 May 29;54(1):17. doi: 10.1186/s40659-021-00341-7
Epub:
Not Epub
Abstract:
Background: The MVD gene mutations are identified in porokeratosis, which is considered a skin-specific autoinflammatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong W, Huang Y, Wu Z, Kong Y, Luan J, Zhang Q, Pan J, Yan K, Zhang Z. Mvda is required for zebrafish early development. Biol Res. 2021 May 29;54(1):17. doi: 10.1186/s40659-021-00341-7.

Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies

Authors:
Dworschak GC, Punetha J, Kalanithy JC, Mingardo E, Erdem HB, Akdemir ZC, Karaca E, Mitani T, Marafi D, Fatih JM, Jhangiani SN, Hunter JV, Dakal TC, Dhabhai B, Dabbagh O, Alsaif HS, Alkuraya FS, Maroofian R, Houlden H, Efthymiou S, Dominik N, Salpietro V, Sultan T, Haider S, Bibi F, Thiele H, Hoefele J, Riedhammer KM, Wagner M, Guella I, Demos M, Keren B, Buratti J, Charles P, Nava C, Héron D, Heide S, Valkanas E, Waddell LB, Jones KJ, Oates EC, Cooper ST, MacArthur D, Syrbe S, Ziegler A, Platzer K, Okur V, Chung WK, O'Shea SA, Alcalay R, Fahn S, Mark PR, Guerrini R, Vetro A, Hudson B, Schnur RE, Hoganson GE, Burton JE, McEntagart M, Lindenberg T, Yilmaz Ö, Odermatt B, Pehlivan D, Posey JE, Lupski JR, Reutter H
Citation:
Genet Med. 2021 May 30. doi: 10.1038/s41436-021-01196-9. Online ahead of print
Epub:
Not Epub
Abstract:
Purpose: To investigate the effect of PLXNA1 variants on the phenotype of patients with autosomal dominant and recessive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dworschak GC, Punetha J, Kalanithy JC, Mingardo E, Erdem HB, Akdemir ZC, Karaca E, Mitani T, Marafi D, Fatih JM, Jhangiani SN, Hunter JV, Dakal TC, Dhabhai B, Dabbagh O, Alsaif HS, Alkuraya FS, Maroofian R, Houlden H, Efthymiou S, Dominik N, Salpietro V, Sultan T, Haider S, Bibi F, Thiele H, Hoefele J, Riedhammer KM, Wagner M, Guella I, Demos M, Keren B, Buratti J, Charles P, Nava C, Héron D, Heide S, Valkanas E, Waddell LB, Jones KJ, Oates EC, Cooper ST, MacArthur D, Syrbe S, Ziegler A, Platzer K, Okur V, Chung WK, O'Shea SA, Alcalay R, Fahn S, Mark PR, Guerrini R, Vetro A, Hudson B, Schnur RE, Hoganson GE, Burton JE, McEntagart M, Lindenberg T, Yilmaz Ö, Odermatt B, Pehlivan D, Posey JE, Lupski JR, Reutter H. Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies. Genet Med. 2021 May 30. doi: 10.1038/s41436-021-01196-9. Online ahead of print.

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family

Authors:
Mathieu H, Patten SA, Aragon-Martin JA, Ocaka L, Simpson M, Child A, Moldovan F
Citation:
Sci Rep. 2021 May 26;11(1):11026. doi: 10.1038/s41598-021-90155-0
Epub:
Not Epub
Abstract:
Idiopathic scoliosis (IS) is a complex 3D deformation of the spine with a strong genetic component, most commonly found in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathieu H, Patten SA, Aragon-Martin JA, Ocaka L, Simpson M, Child A, Moldovan F. Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family. Sci Rep. 2021 May 26;11(1):11026. doi: 10.1038/s41598-021-90155-0.

CX3CR1 is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats

Authors:
Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S
Citation:
J Virol. 2021 May 26:JVI0001021. doi: 10.1128/JVI.00010-21. Online ahead of print
Epub:
Not Epub
Abstract:
Respiratory syncytial virus (RSV) has been reported to use CX3CR1 in vitro as a receptor on cultured primary human airway...
Delivery Method:
peptide-linked
Organism or Cell Type:
Sigmodon sp. (Cotton rat)
Citation Extract:
Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S. CX3CR1 is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats. J Virol. 2021 May 26:JVI0001021. doi: 10.1128/JVI.00010-21. Online ahead of print.

Rab35 regulates skeletogenesis and gastrulation by facilitating actin remodeling and vesicular trafficking

Authors:
Remsburg C, Testa M, Song JL
Citation:
Cells Dev. 2021 Mar;165:203660. doi: 10.1016/j.cdev.2021.203660. Epub 2021 Jan 18
Epub:
Not Epub
Abstract:
Rab35 is a small GTPase that regulates plasma membrane to early endosome vesicular trafficking and mediates actin remodeling to...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Remsburg C, Testa M, Song JL. Rab35 regulates skeletogenesis and gastrulation by facilitating actin remodeling and vesicular trafficking. Cells Dev. 2021 Mar;165:203660. doi: 10.1016/j.cdev.2021.203660. Epub 2021 Jan 18.

FASCIN regulates actin assembly for spindle movement and polar body extrusion in mouse oocyte meiosis

Authors:
Hu LL, Pan MH, Yang FL, Zong ZA, Tang F, Pan ZN, Lu X, Ren YP, Wang JL, Sun SC
Citation:
J Cell Physiol. 2021 May 21. doi: 10.1002/jcp.30443. Online ahead of print
Epub:
Not Epub
Abstract:
During mouse oocyte meiotic maturation, actin filaments play multiple roles in meiosis such as spindle migration and...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hu LL, Pan MH, Yang FL, Zong ZA, Tang F, Pan ZN, Lu X, Ren YP, Wang JL, Sun SC. FASCIN regulates actin assembly for spindle movement and polar body extrusion in mouse oocyte meiosis. J Cell Physiol. 2021 May 21. doi: 10.1002/jcp.30443. Online ahead of print.

Crosstalk between Fat Mass and Obesity-related (FTO) and multiple WNT signaling pathways

Authors:
Kim H, Jang S, Lee Y-s
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.20.444911
Epub:
Not Epub
Abstract:
Fat Mass and Obesity-related (FTO) gene is associated with a diverse set of human diseases. Yet, the functional landscape of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H, Jang S, Lee Y-s. Crosstalk between Fat Mass and Obesity-related (FTO) and multiple WNT signaling pathways. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.20.444911 .

Golden pompano genome resource enables discovery of valuable gene determining growth traits

Authors:
Luo H, Zhang Y, Ji C, Zhao Y, Peng J, Xu Y, Chen X, Huang Y, Liu Q, He P, Feng P, Yang C, Wei P, Yu H, Zheng H, Lin Y, Chen X
Citation:
bioRxiv. 2021;[preprint]. doi:10.1101/2021.05.20.445047
Epub:
Not Epub
Abstract:
One important goal of fish genetic breeding is to identify valuable loci and genes that can facilitate growth and thereby...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luo H, Zhang Y, Ji C, Zhao Y, Peng J, Xu Y, Chen X, Huang Y, Liu Q, He P, Feng P, Yang C, Wei P, Yu H, Zheng H, Lin Y, Chen X. Golden pompano genome resource enables discovery of valuable gene determining growth traits. bioRxiv. 2021;[preprint]. doi:10.1101/2021.05.20.445047.

Mechanisms underlying microglial colonization of developing neural retina in zebrafish

Authors:
Ranawat N, Masai I
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.20.444912
Epub:
Not Epub
Abstract:
Microglia are brain-resident macrophages that function as the first line of defense in brain. Embryonic microglial precursors...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ranawat N, Masai I. Mechanisms underlying microglial colonization of developing neural retina in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.20.444912.

CD9 tetraspanins convey robustness to CXCR4b signalling during collective cell migration

Authors:
Marsay KS, Greaves S, Roehl H, Monk PN, Carney TJ, Partridge LJ
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444012
Epub:
Not Epub
Abstract:
Collective cell migration is essential for embryonic development and homeostatic processes. During zebrafish development, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marsay KS, Greaves S, Roehl H, Monk PN, Carney TJ, Partridge LJ. CD9 tetraspanins convey robustness to CXCR4b signalling during collective cell migration. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444012 .

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