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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury
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Citation:
Exp Biol Med (Maywood). 2021 Mar 9:1535370221997071. doi: 10.1177/1535370221997071. Online ahead of print Epub:
Not Epub Abstract:
This study aims to examine whether miR-31 promotes endogenous NSC proliferation and be used for spinal cord injury management.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Gao Y, Tian F, Du R, Yuan Y, Li P, Liu F, Wang C. miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury. Exp Biol Med (Maywood). 2021 Mar 9:1535370221997071. doi: 10.1177/1535370221997071. Online ahead of print. |
Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury
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Citation:
bioRxiv. 2021;[preprint] doi:/10.1101/2021.03.11.435053 Epub:
Not Epub Abstract:
Unlike mammals, zebrafish can regenerate a damaged retina. Key to this regenerative response are Müller glia (MG) that divide... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Goldman D, Sahu A, Devi S, Jui J. Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury. bioRxiv. 2021;[preprint] doi:/10.1101/2021.03.11.435053. |
Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome
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Citation:
Nat Med. 2021;[Epub ahead of print] doi:10.1038/s41591-021-01262-4 Epub:
Yes Abstract:
Hutchinson–Gilford progeria syndrome (HGPS) is a rare, invariably fatal childhood premature aging disorder caused by a pre-... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Puttaraju M, Jackson M, Klein S, Shilo A, Bennett CF, Gordon L, Rigo F, Misteli T. Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome. Nat Med. 2021;[Epub ahead of print] doi:10.1038/s41591-021-01262-4. |
A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome
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Citation:
Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11. Epub:
Not Epub Abstract:
Hutchinson–Gilford progeria syndrome (HGPS) is a rare accelerated aging disorder characterized by premature death from... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: human progeric fibroblasts, mice Citation Extract: Erdos MR, Cabral WA, Tavarez UL, Cao K, Gvozdenovic-Jeremic J, Narisu N, Zerfas PM, Crumley S, Boku Y, Hanson G, Mourich DV, Kole R, Eckhaus MA, Gordon LB, Collins FS. A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome. Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11.. |
Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart development
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.10.434727 Epub:
Not Epub Abstract:
During early vertebrate heart development, the heart transitions from a linear tube to a complex asymmetric structure. This... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Derrick CJ, Pollitt EJG, Uruchurtu ASS, Hussein F, Noel ES. Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart development. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.10.434727 . |
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients
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Citation:
EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328 Epub:
Not Epub Abstract:
DMD is a rare disorder characterized by progressive muscle degeneration and premature death. Therapy development is delayed by... Delivery Method:
i.v. injection Organism or Cell Type:
mice mdx Citation Extract: Signorelli M, Ebrahimpoor M, Veth O, Hettne K, Verwey N, García‐Rodríguez R, Tanganyika‐deWinter CL, Lopez Hernandez LB, Cedillo RE, Díaz BG, Magnusson OT, Mei H, Tsonaka R, Aartsma‐Rus A, Spitali P. Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients. EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328. |
Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families
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Citation:
Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061 Epub:
Not Epub Abstract:
Isolated Microspherophakia (MSP) is an autosomal recessive disorder characterised by a smaller than normal spherical lens. Till... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Madhangi M, Dutta D, Show S, Bhat VK, Rather MI, Tiwari A, Singh N, Duvvari MR, Murthy GJ, Kumar A, Nongthomba U. Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families. Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061. |
An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo
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Citation:
Development. 2021;dev.191197 doi:10.1242/dev.191197 Epub:
Yes Abstract:
Activation of Wnt/β-catenin (cWnt) signaling at the future posterior end of early bilaterian embryos is a highly conserved... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus & Lytechinus variegatus (sea urchin) Citation Extract: Sun H, Peng CFJ, Wang L, Feng H, Wikramanayake AH
. An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo. Development. 2021;dev.191197 doi:10.1242/dev.191197. |
Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss
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Citation:
JCI Insight. 2021 Mar 8;6(5):141561. doi: 10.1172/jci.insight.141561 Epub:
Not Epub Abstract:
Hair cell loss is the leading cause of hearing and balance disorders in humans. It can be caused by many factors, including... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zallocchi M, Hati S, Xu Z, Hausman W, Liu H, He DZ, Zuo J. Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss. JCI Insight. 2021 Mar 8;6(5):141561. doi: 10.1172/jci.insight.141561. |
The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.04.433320 Epub:
Not Epub Abstract:
The enpp ectonucleotidases regulate lipidic and purinergic signalling pathways by controlling the extracellular concentrations... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA. The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.04.433320. |