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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations
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Citation:
Elife. 2021 May 20;10:e62155. doi: 10.7554/eLife.62155. Online ahead of print Epub:
Not Epub Abstract:
Mosaic inactivation of CCM2 in humans causes cerebral cavernous malformations (CCMs) containing adjacent dilated blood-filled... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 May 20;10:e62155. doi: 10.7554/eLife.62155. Online ahead of print. |
Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism
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Citation:
Endocrinology. 2021 May 21:bqab101. doi: 10.1210/endocr/bqab101. Online ahead of print Epub:
Yes Abstract:
Congenital hypothyroidism (CH) is a highly prevalent but treatable neonatal endocrine disorder. Thyroid dyshormonogenesis is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun F, Fang Y, Zhang MM, Zhang RJ, Wu FY, Yang RM, Tu PH, Dong M, Zhao SX, Song HD. Genetic Manipulation on Zebrafish duox Recapitulate the Clinical Manifestations of Congenital Hypothyroidism. Endocrinology. 2021 May 21:bqab101. doi: 10.1210/endocr/bqab101. Online ahead of print. |
Polarized Dishevelled dissolution and condensation drives embryonic axis specification in oocytes
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.17.444558 Epub:
Not Epub Abstract:
The organismal body axes that are formed during embryogenesis are intimately linked to intrinsic asymmetries established at the... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Swartz Z, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake A, Cheeseman IM. Polarized Dishevelled dissolution and condensation drives embryonic axis specification in oocytes. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.17.444558 . |
Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.17.444306 Epub:
Not Epub Abstract:
Many key signaling molecules used to build tissues during embryonic development are re-activated at injury sites to stimulate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heller IS, Guenther CA, Meireles AM, Talbot WS, Kingsley DM. Characterization of mouse Bmp5 regulatory injury element in zebrafish wound models. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.17.444306 . |
Interferon tau: Influences on growth and development of the conceptus
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Citation:
Theriogenology. 2020;150:75-83. doi:10.1016/j.theriogenology.2020.01.069 Epub:
Not Epub Abstract:
Interferon tau (IFNT), the pregnancy recognition signal secreted from trophectoderm cells of ruminant conceptuses abrogates the... Organism or Cell Type:
Ovis aries (sheep) conceptus Citation Extract: Bazer FW, Seo H, Wu G, Johnson GA. Interferon tau: Influences on growth and development of the conceptus. Theriogenology. 2020;150:75-83. doi:10.1016/j.theriogenology.2020.01.069. |
The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
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Citation:
Cells. 2021;10(5):1233. doi:10.3390/cells10051233 Epub:
Not Epub Abstract:
SMYD3 (SET and MYND domain containing protein 3) is a methylase over-expressed in cancer cells and involved in oncogenesis.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fittipaldi R, Floris P, Proserpio V, Cotelli F, Beltrame M, Caretti G. The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development. Cells. 2021;10(5):1233. doi:10.3390/cells10051233 . |
A newly identified Rab-GDI paralogue has a role in neural development in amphibia
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Citation:
Gene. 2017 Jan 30;599:78-86. doi: 10.1016/j.gene.2016.11.013. Epub 2016 Nov 9 Epub:
Not Epub Abstract:
Vesicle shuttling is critical for many cellular and organismal processes, including embryonic development. GDI proteins... Organism or Cell Type:
Xenopus Citation Extract: Nazlamova L, Noble A, Schubert FR, McGeehan J, Myers F, Guille M, Scarlett G. A newly identified Rab-GDI paralogue has a role in neural development in amphibia. Gene. 2017 Jan 30;599:78-86. doi: 10.1016/j.gene.2016.11.013. Epub 2016 Nov 9. |
Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation
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Citation:
Sci Adv. 2021 May 14;7(20):eabg2099. doi: 10.1126/sciadv.abg2099. Print 2021 May Epub:
Not Epub Abstract:
The four-pass transmembrane proteins Vangl1 and Vangl2 are dedicated core components of Wnt/planar cell polarity (Wnt/PCP)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Feng D, Wang J, Yang W, Li J, Lin X, Zha F, Wang X, Ma L, Choi NT, Mii Y, Takada S, Huen MSY, Guo Y, Zhang L, Gao B. Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation. Sci Adv. 2021 May 14;7(20):eabg2099. doi: 10.1126/sciadv.abg2099. Print 2021 May. |
Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443743 Epub:
Not Epub Abstract:
The control of mRNA stability plays a central role in regulating gene expression patterns. Recent studies have revealed that... Organism or Cell Type:
zebrafish Citation Extract: Mishima Y, Han P, Kimura S, Iwasaki S. Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443743. |
The STING ligand 2′3′-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.13.443009 Epub:
Not Epub Abstract:
In mammals, the cGAS-cGAMP-STING pathway is crucial for sensing viral infection and initiating an anti-viral type I interferon... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (anemone) Citation Extract: Margolis SR, Dietzen PA, Hayes BM, Wilson SC, Remick BC, Chou S, Vance RE. The STING ligand 2′3′-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.13.443009. |