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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Glypican 4 regulates planar cell polarity of endoderm cells by controlling the localization of Cadherin 2

Authors:
Balaraju AK, Hu B, Rodriguez JJ, Murry M, Lin F
Citation:
Development. 2021 Jul 15;148(14):dev199421. doi: 10.1242/dev.199421. Epub 2021 Jul 12
Epub:
Not Epub
Abstract:
Noncanonical Wnt/planar cell polarity (Wnt/PCP) signaling has been implicated in endoderm morphogenesis. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Balaraju AK, Hu B, Rodriguez JJ, Murry M, Lin F. Glypican 4 regulates planar cell polarity of endoderm cells by controlling the localization of Cadherin 2. Development. 2021 Jul 15;148(14):dev199421. doi: 10.1242/dev.199421. Epub 2021 Jul 12.

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Authors:
Kreis J, Wielath FM, Vick P
Citation:
Biol Open. 2021 Jul 15;10(7):bio056887. doi: 10.1242/bio.056887. Epub 2021 Jul 12
Epub:
Not Epub
Abstract:
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kreis J, Wielath FM, Vick P. Rab7 is required for mesoderm patterning and gastrulation in Xenopus. Biol Open. 2021 Jul 15;10(7):bio056887. doi: 10.1242/bio.056887. Epub 2021 Jul 12.

Temporal regulation of Pten is essential for retina regeneration in zebrafish

Authors:
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijithkumar V, Ramachandran R
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.09.451767
Epub:
Not Epub
Abstract:
Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after an acute injury. Retina regeneration...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijithkumar V, Ramachandran R. Temporal regulation of Pten is essential for retina regeneration in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.09.451767.

Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis

Authors:
Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA
Citation:
J Am Soc Nephrol. 2021 Apr 28:ASN.2020101525. doi: 10.1681/ASN.2020101525. Online ahead of print
Epub:
Yes
Abstract:
Background: Podocytes are critical to maintaining the glomerular filtration barrier, and mutations in nephrotic syndrome genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA. Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis. J Am Soc Nephrol. 2021 Apr 28:ASN.2020101525. doi: 10.1681/ASN.2020101525. Online ahead of print.

The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system

Authors:
Carretero-Rodriguez L, Guðjónsdóttir R, Poparic I, Reilly ML, Chol M, Bianco IH, Chiapello M, Feret R, Deery MJ, Guthrie S
Citation:
J Neurosci. 2021;41(31):6652-6672. doi: 10.1523/JNEUROSCI.0983-19.2021. Online ahead of print
Epub:
Not Epub
Abstract:
A precise sequence of axon guidance events is required for the development of the ocular motor system. Three cranial nerves...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carretero-Rodriguez L, Guðjónsdóttir R, Poparic I, Reilly ML, Chol M, Bianco IH, Chiapello M, Feret R, Deery MJ, Guthrie S. The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system. J Neurosci. 2021;41(31):6652-6672. doi: 10.1523/JNEUROSCI.0983-19.2021. Online ahead of print.

Microinjection of Xenopus tropicalis Embryos

Authors:
Lane M, Mis EK, Khokha MK
Citation:
Cold Spring Harb Protoc. 2021 Jul 8. doi: 10.1101/pdb.prot107644. Online ahead of print
Epub:
Yes
Abstract:
Microinjection is an important technique used to study development in the oocyte and early embryo. In Xenopus, substances such...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Lane M, Mis EK, Khokha MK. Microinjection of Xenopus tropicalis Embryos. Cold Spring Harb Protoc. 2021 Jul 8. doi: 10.1101/pdb.prot107644. Online ahead of print.

Future Physiology 2020 (Virutal) Oral Communications: A zebrafish model of embryonic growth disruption reveals an ongoing impact on metabolic and cardiac phenotype

Authors:
Evans B
Citation:
Proc Physiol Soc. 2020;46:OC03
Epub:
Not Epub
Abstract:
As climate change continues to pose a global problem, the need to understand organisms immediate and ongoing responses to the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Evans B. Future Physiology 2020 (Virutal) Oral Communications: A zebrafish model of embryonic growth disruption reveals an ongoing impact on metabolic and cardiac phenotype. Proc Physiol Soc. 2020;46:OC03.

Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor

Authors:
Leventea E, Zhu Z, Fang X, Nikolaeva Y, Markham E, Hirst RA, van Eeden FJM, Malicki JJ
Citation:
https://www.pnas.org/content/118/28/e2102562118
Epub:
Not Epub
Abstract:
Here, we report that important regulators of cilia formation and ciliary compartment-directed protein transport function in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leventea E, Zhu Z, Fang X, Nikolaeva Y, Markham E, Hirst RA, van Eeden FJM, Malicki JJ. Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor. https://www.pnas.org/content/118/28/e2102562118.

Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

Authors:
Hahn I, Voelzmann A, Parkin J, Fuelle J, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A
Citation:
PLoS Genet. 2021;17(7):e1009647. doi:10.1371/journal.pgen.1009647
Epub:
Not Epub
Abstract:
The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hahn I, Voelzmann A, Parkin J, Fuelle J, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A. Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. PLoS Genet. 2021;17(7):e1009647. doi:10.1371/journal.pgen.1009647.

Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling

Authors:
Serifi I, Besta S, Karetsou Z, Giardoglou P, Beis D, Niewiadomski P, Papamarcaki T
Citation:
Sci Rep. 2021 Jul 6;11(1):13940. doi: 10.1038/s41598-021-93440-0
Epub:
Not Epub
Abstract:
The Hedgehog (Hh)/Gli signaling pathway controls cell proliferation and differentiation, is critical for the development of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serifi I, Besta S, Karetsou Z, Giardoglou P, Beis D, Niewiadomski P, Papamarcaki T. Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling. Sci Rep. 2021 Jul 6;11(1):13940. doi: 10.1038/s41598-021-93440-0.

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