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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish
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Citation:
Endocrinology. 2021;[epub] doi:10.1210/endocr/bqab258 Epub:
Yes Abstract:
Cytochrome P45011A1, encoded by Cyp11a1, converts cholesterol to pregnenolone (P5), the first and rate-limiting step in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Ye D, Zhang F, Zhang R, Zhu J, Wang H, He M, Sun Y. Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 2021;[epub] doi:10.1210/endocr/bqab258. |
Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs
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Citation:
Sci Adv. 2021;7(52):eabl3858 doi:10.1126/sciadv.abl3858 Epub:
Not Epub Abstract:
Marked epigenetic reprogramming is essential to convert terminally differentiated gametes to totipotent embryos. It remains... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu X, Zhang H, Zhang B, Zhang Y, Wang Q, Shen W, Wu X, Li L, Xia W, Nakamura R, Liu B, Liu F, Takeda H, Meng A, Xie W. Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs. Sci Adv. 2021;7(52):eabl3858 doi:10.1126/sciadv.abl3858. |
Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis
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Citation:
Cell. 2021;184(26):6313-25. doi:10.1016/j.cell.2021.11.025 Epub:
Not Epub Abstract:
How tissues acquire complex shapes is a fundamental question in biology and regenerative medicine. Zebrafish semicircular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Munjal A, Hannezo A, Tsai TY-C, Mitchison TJ, Megason SG. Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis. Cell. 2021;184(26):6313-25. doi:10.1016/j.cell.2021.11.025. |
l-selenomethionine induces zebrafish embryo cardiovascular defects via down-regulating expression of lrp2b
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Citation:
Chemosphere. 2021 Dec 18:133351. doi: 10.1016/j.chemosphere.2021.133351. Online ahead of print Epub:
Yes Abstract:
Selenium plays crucial roles in maintaining the growth and development of vertebrates including humans. However, excessive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao G, Zhu Y, Hu J, Gao M, Hong Y. l-selenomethionine induces zebrafish embryo cardiovascular defects via down-regulating expression of lrp2b. Chemosphere. 2021 Dec 18:133351. doi: 10.1016/j.chemosphere.2021.133351. Online ahead of print. |
Knockdown and Knockout of Tissue Factor Pathway Inhibitor in Zebrafish
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Citation:
Thromb Haemost. 2021 Dec 16. doi: 10.1055/a-1723-4075. Online ahead of print Epub:
Yes Abstract:
Tissue Factor Pathway Inhibitor (TFPI) is an anticoagulant that inhibits factor VIIa and Xa in the blood coagulation pathways.... Delivery Method:
Vivo-Morpholino piggyback hybrid Organism or Cell Type:
zebrafish Citation Extract: Raman R, Fallatah W, Al Qaryoute A, Ryon M, Jagadeeswaran P. Knockdown and Knockout of Tissue Factor Pathway Inhibitor in Zebrafish. Thromb Haemost. 2021 Dec 16. doi: 10.1055/a-1723-4075. Online ahead of print. |
A novel role of PRL in regulating epithelial cell density by inducing apoptosis at confluence
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Citation:
J Cell Sci. 2021 Dec 21:jcs.258550. doi: 10.1242/jcs.258550. Online ahead of print Epub:
Yes Abstract:
Maintaining proper epithelial cell density is essential for the survival of multicellular organisms. While regulation of cell... Organism or Cell Type:
zebrafish Citation Extract: Lohani S, Funato Y, Akieda Y, Mizutani K, Takai Y, Ishitani T, Miki H. A novel role of PRL in regulating epithelial cell density by inducing apoptosis at confluence. J Cell Sci. 2021 Dec 21:jcs.258550. doi: 10.1242/jcs.258550. Online ahead of print. |
Novel pre-clinical model for CDKL5 Deficiency Disorder
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Citation:
Dis Model Mech 2021;[Epub] doi:10.1242/dmm.049094 Epub:
Yes Abstract:
Cyclin-Dependent Kinase-Like-5 (CDKL5) Deficiency Disorder (CDD) is a severe X-linked neurodegenerative disease characterized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Serrano RJ, Lee C, Douek AM, Kaslin J, Bryson-Richardson RJ, Sztal TE. Novel pre-clinical model for CDKL5 Deficiency Disorder. Dis Model Mech 2021;[Epub] doi:10.1242/dmm.049094. |
Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos
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Citation:
Dev Cell. 2021;[Epub] doi:10.1016/j.devcel.2021.11.021 Epub:
Yes Abstract:
How embryos scale patterning according to size is still not fully understood. Through in silico screening and analysis of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Orlov EE, Nesterenko AM, Korotkova DD, Parshina EA, Martynova NY, Zaraisky AG. Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos. Dev Cell. 2021;[Epub] doi:10.1016/j.devcel.2021.11.021. |
Who is the best surrogate for germ stem cell transplantation in fish?
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Citation:
Aquaculture. 2022;549:737759. [Epub] doi:10.1016/j.aquaculture.2021.737759 Epub:
Yes Abstract:
Surrogate broodstock technology in fishes has potential for aquaculture as well as endangered species conservation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička. Who is the best surrogate for germ stem cell transplantation in fish?. Aquaculture. 2022;549:737759. [Epub] doi:10.1016/j.aquaculture.2021.737759. |
TNNT1 myopathy with novel compound heterozygous mutations
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Citation:
Neuromuscul Disord. 2021;[Epub ahead of print] doi:10.1016/j.nmd.2021.12.003 Epub:
Not Epub Abstract:
Nemaline myopathies are clinically and genetically heterogeneous disorders caused by several different genes. One of them is... Organism or Cell Type:
zebrafish Citation Extract: Lee S, Eum J, Park S, Ki S, Hwang BJ, Kee Y, Chae JH. TNNT1 myopathy with novel compound heterozygous mutations. Neuromuscul Disord. 2021;[Epub ahead of print] doi:10.1016/j.nmd.2021.12.003. |