You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Tubulin acetylation promotes penetrative capacity of cells undergoing radial intercalation
|
Citation:
Cell Rep. 2021 Aug 17;36(7):109556. doi: 10.1016/j.celrep.2021.109556 Epub:
Not Epub Abstract:
Post-translational modification of tubulin provides differential functions to microtubule networks. Here, we address the role... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Collins C, Kim SK, Ventrella R, Carruzzo HM, Wortman JC, Han H, Suva EE, Mitchell JW, Yu CC, Mitchell BJ. Tubulin acetylation promotes penetrative capacity of cells undergoing radial intercalation. Cell Rep. 2021 Aug 17;36(7):109556. doi: 10.1016/j.celrep.2021.109556. |
RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2
|
Citation:
Mov Disord. 2021 Aug 14. doi: 10.1002/mds.28729. Online ahead of print Epub:
Not Epub Abstract:
Background: Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease caused by expansion of a CAG repeat in Ataxin-2... Citation Extract: Li PP, Moulick R, Feng H, Sun X, Arbez N, Jin J, Marque LO, Hedglen E, Chan HYE, Ross CA, Pulst SM, Margolis RL, Woodson S, Rudnicki DD. RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2. Mov Disord. 2021 Aug 14. doi: 10.1002/mds.28729. Online ahead of print. |
Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease
|
Citation:
Int J Mol Sci. 2021 Aug 20;22(16):9013. doi: 10.3390/ijms22169013 Epub:
Not Epub Abstract:
In autosomal dominant polycystic kidney disease (ADPKD), kidney cyst growth requires the recruitment of CFTR (cystic fibrosis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oliveira I, Jacinto R, Pestana S, Nolasco F, Calado J, Lopes SS, Roxo-Rosa M. Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease. Int J Mol Sci. 2021 Aug 20;22(16):9013. doi: 10.3390/ijms22169013. |
Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification
|
Citation:
Elife. 2021 Aug 17;10:e65758. doi: 10.7554/eLife.65758 Epub:
Not Epub Abstract:
To investigate the role of the vasculature in pancreatic β-cell regeneration, we crossed a zebrafish β-cell ablation model into... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu KC, Villasenor A, Bertuzzi M, Schmitner N, Radros N, Rautio L, Mattonet K, Matsuoka RL, Reischauer S, Stainier DY, Andersson O. Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification. Elife. 2021 Aug 17;10:e65758. doi: 10.7554/eLife.65758. |
Dual SMN inducing therapies can rescue survival and motor unit function in symptomatic ∆7SMA mice
|
Citation:
Neurobiol Dis. 2021 Aug 20;159:105488. doi: 10.1016/j.nbd.2021.105488. Online ahead of print Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by survival motor neuron (SMN) protein deficiency... Delivery Method:
intracerebroventricular (icv) injection Organism or Cell Type:
mice Citation Extract: Kray KM, McGovern VL, Chugh D, Arnold WD, Burghes AHM. Dual SMN inducing therapies can rescue survival and motor unit function in symptomatic ∆7SMA mice. Neurobiol Dis. 2021 Aug 20;159:105488. doi: 10.1016/j.nbd.2021.105488. Online ahead of print. |
The alternative oxidase (AOX) increases sulphide tolerance in the highly invasive marine invertebrate Ciona intestinalis
|
Citation:
J Exp Biol. 2021 Aug 15;224(16):jeb242985. doi: 10.1242/jeb.242985. Epub 2021 Aug 26 Epub:
Not Epub Abstract:
Ecological communities and biodiversity are shaped by both abiotic and biotic factors. This is well illustrated by extreme... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis Citation Extract: Bremer K, Yasuo H, Debes PV, Jacobs HT. The alternative oxidase (AOX) increases sulphide tolerance in the highly invasive marine invertebrate Ciona intestinalis. J Exp Biol. 2021 Aug 15;224(16):jeb242985. doi: 10.1242/jeb.242985. Epub 2021 Aug 26. |
Vivo-Morpholino-Based Antiviral for SARS-CoV-2: Implications for Novel Therapies in the Treatment of Acute COVID-19 Disease
|
Citation:
Biomedicines. 2021;9(8):1018. doi:10.3390/biomedicines9081018 Epub:
Not Epub Abstract:
Therapeutic modalities designed specifically to inhibit COVID-19 infection and replication would limit progressive COVID-19-... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Vero E6 Citation Extract: Hildreth JEK, Moulton JD, Alcendor DJ. Vivo-Morpholino-Based Antiviral for SARS-CoV-2: Implications for Novel Therapies in the Treatment of Acute COVID-19 Disease. Biomedicines. 2021;9(8):1018. doi:10.3390/biomedicines9081018. |
Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability
|
Citation:
PLoS ONE. 2021;16(8):e0256181. doi:journal.pone.0256181 Epub:
Not Epub Abstract:
Identifying causative variants in cis-regulatory elements (CRE) in neurodevelopmental disorders has proven challenging. We have... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bengani H, Grozeva D, Moyon L, Bhatia S, Louros SR, Hope J, Jackson A, Prendergast JG, Owen LJ, Naville M, Rainger J, Grimes G, Halachev M, Murphy, Spasic-Boskovic O, van Heyningen V, Kind P, Abbott CM, Osterweil E, Raymond FL, Crollius HR, FitzPatrick DR. Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability. PLoS ONE. 2021;16(8):e0256181. doi:journal.pone.0256181. |
Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body
|
Citation:
Dev Bio. 2021;[Epub} doi:10.1016/j.ydbio.2021.08.002 Epub:
Not Epub Abstract:
The neural crest (NC) is a transient multipotent cell population that migrates extensively to produce a remarkable array of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rocha M, Kushkowski E, Schnirman R, Booth C, Singh N, Beadell A, Prince VE. Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body. Dev Bio. 2021;[Epub} doi:10.1016/j.ydbio.2021.08.002. |
Open reading frame correction using antisense oligonucleotides for the treatment of cystic fibrosis caused by CFTR-W1282X
|
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.11.455834 Epub:
Not Epub Abstract:
CFTR gene mutations that result in the introduction of premature termination codons (PTCs) are common in cystic fibrosis (CF).... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: CFTR-W1282X bronchial epithelial line, primary CFTR-W1282X epithelial cells Citation Extract: Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Open reading frame correction using antisense oligonucleotides for the treatment of cystic fibrosis caused by CFTR-W1282X. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.11.455834. |