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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis
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Citation:
iScience. 2022 Mar 19;25(4):104123. doi: 10.1016/j.isci.2022.104123. PMID: 35402867; PMCID: PMC8987407 Epub:
Not Epub Abstract:
During canonical Wnt signaling, the Wnt receptor complex is sequestered together with glycogen synthase kinase 3 (GSK3) and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Tejeda-Muñoz N, Morselli M, Moriyama Y, Sheladiya P, Pellegrini M, De Robertis EM. Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis. iScience. 2022 Mar 19;25(4):104123. doi: 10.1016/j.isci.2022.104123. PMID: 35402867; PMCID: PMC8987407. |
Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning
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Citation:
Development. 2021 Dec 21:dev.200195. doi: 10.1242/dev.200195. Online ahead of print Epub:
Yes Abstract:
Endothelial cell migration and proliferation are essential for the establishment of a hierarchical organization of blood... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rosa A, Giese W, Meier K, Alt S, Klaus-Bergmann A, Edgar LT, Bartels E, Collins R, Szymborska A, Coxam B, Bernabeu MO, Gerhardt H. Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning. Development. 2021 Dec 21:dev.200195. doi: 10.1242/dev.200195. Online ahead of print. |
Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression
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Citation:
Angiogenesis. 2022 Jan 16. doi: 10.1007/s10456-021-09827-0. Online ahead of print Epub:
Yes Abstract:
Molecular transport and cell circulation between tissues and organs through blood and lymphatic vessels are essential for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tai Z, Li L, Zhao G, Liu JX. Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression. Angiogenesis. 2022 Jan 16. doi: 10.1007/s10456-021-09827-0. Online ahead of print. |
KEPI Plays a Negative Role in the Repression that Accompanies Translational Inhibition Guided by the uORF Element of Human chop Transcript during Stress Response
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Citation:
Gene. 2022 Jan 11:146160. doi: 10.1016/j.gene.2021.146160. Online ahead of print Epub:
Yes Abstract:
Translation of the downstream coding sequence of some mRNAs may be repressed by the upstream open reading frame (uORF) at their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee HC, Hsieh CC, Tsai HJ. KEPI Plays a Negative Role in the Repression that Accompanies Translational Inhibition Guided by the uORF Element of Human chop Transcript during Stress Response. Gene. 2022 Jan 11:146160. doi: 10.1016/j.gene.2021.146160. Online ahead of print. |
Tfap2b specifies an embryonic melanocyte stem cell that retains adult multifate potential
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Citation:
Cell Rep. 2022 Jan 11;38(2):110234. doi: 10.1016/j.celrep.2021.110234 Epub:
Not Epub Abstract:
Melanocytes, the pigment-producing cells, are replenished from multiple stem cell niches in adult tissue. Although pigmentation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brombin A, Simpson DJ, Travnickova J, Brunsdon H, Zeng Z, Lu Y, Young AIJ, Chandra T, Patton EE. Tfap2b specifies an embryonic melanocyte stem cell that retains adult multifate potential. Cell Rep. 2022 Jan 11;38(2):110234. doi: 10.1016/j.celrep.2021.110234. |
Numb is required for optimal contraction of skeletal muscle
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Citation:
J Cachexia Sarcopenia Muscle. 2022 Jan 9. doi: 10.1002/jcsm.12907. Online ahead of print Epub:
Yes Abstract:
Background: The role of Numb, a protein that is important for cell fate and development and that, in human muscle, is expressed... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: mouse primary myoblasts, myotubes Citation Extract: De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu XH, Guo L, Zhang B, Ko F, Raczkowski AM, Bauman WA, Goulbourne CN, Zhao W, Brotto M, Cardozo CP. Numb is required for optimal contraction of skeletal muscle. J Cachexia Sarcopenia Muscle. 2022 Jan 9. doi: 10.1002/jcsm.12907. Online ahead of print. |
An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes
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Citation:
Nat Commun. 2022 Jan 10;13(1):101. doi: 10.1038/s41467-021-27625-6 Epub:
Not Epub Abstract:
A Variant Surface Glycoprotein (VSG) coat protects bloodstream form Trypanosoma brucei. Prodigious amounts of VSG mRNA (~7-10%... Delivery Method:
electroporation Organism or Cell Type:
Trypanosoma brucei Citation Extract: Budzak J, Jones R, Tschudi C, Kolev NG, Rudenko G. An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes. Nat Commun. 2022 Jan 10;13(1):101. doi: 10.1038/s41467-021-27625-6. |
Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity
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Citation:
Cell Cycle. 2022;[Epub] doi:10.1080/15384101.2021.2023304 Epub:
Yes Abstract:
Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanchez AC, Thren ED, Iovine MK, Skibbens RV. Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity. Cell Cycle. 2022;[Epub] doi:10.1080/15384101.2021.2023304. |
Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis
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Citation:
Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119 Epub:
Not Epub Abstract:
CFTR gene mutations that result in the introduction of premature termination codons (PTCs) are common in cystic fibrosis (CF).... Delivery Method:
Endo-Porter, osmotic shock Organism or Cell Type:
cell culture: CFF16hBEge-W1282X-SCC:3F2, primary hBE Citation Extract: Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119. |
Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans
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Citation:
J Dermatol Sci. 2022 Jan 5:S0923-1811(22)00001-9. doi: 10.1016/j.jdermsci.2022.01.001. Online ahead of print Epub:
Yes Abstract:
Background: Mutations in the genes that encode the human γ-secretase subunits Presenilin-1, Presenilin Enhancer Protein 2, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hermasch MA, Janning H, Perera RP, Schnabel V, Rostam N, Ramos-Gomes F, Muschalek W, Bennemann A, Alves F, Ralser DJ, Betz RC, Schön MP, Dosch R, Frank J. Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans. J Dermatol Sci. 2022 Jan 5:S0923-1811(22)00001-9. doi: 10.1016/j.jdermsci.2022.01.001. Online ahead of print. |