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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity

Authors:
Quillien A, Boulet M, Ethuin S, Vandel L
Citation:
PLoS Genet. 2021;17(6):e1009641 doi:10.1371/journal.pgen.1009641
Epub:
Not Epub
Abstract:
During development, the vertebrate vasculature undergoes major growth and remodeling. While the transcriptional cascade...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quillien A, Boulet M, Ethuin S, Vandel L. Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity. PLoS Genet. 2021;17(6):e1009641 doi:10.1371/journal.pgen.1009641.

Tfap2b specifies an embryonic melanocyte stem cell population that retains adult multi-fate potential

Authors:
Brombin A, Simpson DJ, Travnickova J, Brunsdon HR, Zeng Z, Lu Y, Chandra T, Patton EE
Citation:
bioRxiv. 2021;[preprint] doi: https://doi.org/10.1101/2021.06.18.448859
Epub:
Not Epub
Abstract:
Melanocytes, our pigment producing cells, originate from neural crest-derived progenitors during embryogenesis and from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brombin A, Simpson DJ, Travnickova J, Brunsdon HR, Zeng Z, Lu Y, Chandra T, Patton EE. Tfap2b specifies an embryonic melanocyte stem cell population that retains adult multi-fate potential. bioRxiv. 2021;[preprint] doi: https://doi.org/10.1101/2021.06.18.448859 .

Light-induced, spatiotemporal control of protein in the developing embryo of the sea urchin

Authors:
Wavreil FDM, Poon J, Wessel GM, Yajima M
Citation:
Dev Biol. 2021 Jun 17:S0012-1606(21)00148-2. doi: 10.1016/j.ydbio.2021.06.006. Online ahead of print
Epub:
Not Epub
Abstract:
Differential protein regulation is a critical biological process that regulates cellular activity and controls cell fate...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Wavreil FDM, Poon J, Wessel GM, Yajima M. Light-induced, spatiotemporal control of protein in the developing embryo of the sea urchin. Dev Biol. 2021 Jun 17:S0012-1606(21)00148-2. doi: 10.1016/j.ydbio.2021.06.006. Online ahead of print.

The dual-specificity protein kinase Clk3 is essential for Xenopus neural development

Authors:
Virgirinia RP, Nakamura M, Takebayashi-Suzuki K, Fatchiyah F, Suzuki A
Citation:
Biochem Biophys Res Commun. 2021 Jun 16;567:99-105. doi: 10.1016/j.bbrc.2021.06.005. Online ahead of print
Epub:
Not Epub
Abstract:
During vertebrate development, the formation of the central nervous system (CNS) is initiated by neural induction and...
Organism or Cell Type:
Xenopus
Citation Extract:
Virgirinia RP, Nakamura M, Takebayashi-Suzuki K, Fatchiyah F, Suzuki A. The dual-specificity protein kinase Clk3 is essential for Xenopus neural development. Biochem Biophys Res Commun. 2021 Jun 16;567:99-105. doi: 10.1016/j.bbrc.2021.06.005. Online ahead of print.

Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2

Authors:
Soto RA, Najia MAT, Hachimi M, Frame JM, Yette GA, da Rocha EL, Stankunas K, Daley GQ, North TE
Citation:
Stem Cell Rep. 2021;[Epub] doi:10.1016/j.stemcr.2021.05.014
Epub:
Not Epub
Abstract:
Across species, hematopoietic stem and progenitor cells (HSPCs) arise during embryogenesis from a specialized arterial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Soto RA, Najia MAT, Hachimi M, Frame JM, Yette GA, da Rocha EL, Stankunas K, Daley GQ, North TE. Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2. Stem Cell Rep. 2021;[Epub] doi:10.1016/j.stemcr.2021.05.014.

Association Analysis of Variants of DSCAM and BACE2 With Hirschsprung Disease Susceptibility in Han Chinese and Functional Evaluation in Zebrafish

Authors:
Lu YJ, Yu WW, Cui MM, Yu XX, Song HL, Bai MR, Wu WJ, Gu BL, Wang J, Cai W, Chu X
Citation:
Front Cell Dev Biol. 2021 May 31;9:641152. doi: 10.3389/fcell.2021.641152. eCollection 2021
Epub:
Not Epub
Abstract:
Hirschsprung disease (HSCR) has a higher incidence in children with Down syndrome (DS), which makes trisomy 21 a predisposing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu YJ, Yu WW, Cui MM, Yu XX, Song HL, Bai MR, Wu WJ, Gu BL, Wang J, Cai W, Chu X. Association Analysis of Variants of DSCAM and BACE2 With Hirschsprung Disease Susceptibility in Han Chinese and Functional Evaluation in Zebrafish. Front Cell Dev Biol. 2021 May 31;9:641152. doi: 10.3389/fcell.2021.641152. eCollection 2021.

Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein

Authors:
Pollock NM, Leighton P, Neil G, Allison WT
Citation:
Prion. 2021 Dec;15(1):70-81. doi: 10.1080/19336896.2021.1924557
Epub:
Not Epub
Abstract:
Cellular Prion Protein (PrPC) is a well-studied protein as the substrate for various progressive untreatable neurodegenerative...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pollock NM, Leighton P, Neil G, Allison WT. Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein. Prion. 2021 Dec;15(1):70-81. doi: 10.1080/19336896.2021.1924557.

Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos

Authors:
Ghilardi A, Diana A, Bacchetta R, Santo N, Ascagni M, Prosperi L, Del Giacco L
Citation:
Int J Mol Sci. 2021;22(12):6497. doi:10.3390/ijms22126497
Epub:
Not Epub
Abstract:
The last decade has witnessed the identification of several families affected by hereditary non-syndromic hearing loss (NSHL)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghilardi A, Diana A, Bacchetta R, Santo N, Ascagni M, Prosperi L, Del Giacco L. Inner Ear and Muscle Developmental Defects in Smpx-Deficient Zebrafish Embryos. Int J Mol Sci. 2021;22(12):6497. doi:10.3390/ijms22126497.

Hif1α is required for Wnt regulated gene expression during Xenopus tropicalis tail regeneration

Authors:
Patel JH, Schattinger PA, Takayoshi EE, Wills AE
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444777
Epub:
Not Epub
Abstract:
Regeneration of complex tissues is initiated by an injury-induced stress response, eventually leading to activation of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Patel JH, Schattinger PA, Takayoshi EE, Wills AE. Hif1α is required for Wnt regulated gene expression during Xenopus tropicalis tail regeneration. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444777.

Semaphorin3f as an intrinsic regulator of chamber-specific heart development

Authors:
Halabi R, Cechmanek PB, Hehr CL, McFarlane S
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444704
Epub:
Not Epub
Abstract:
During development a pool of precursors form a heart with atrial and ventricular chambers that exhibit distinct transcriptional...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Halabi R, Cechmanek PB, Hehr CL, McFarlane S. Semaphorin3f as an intrinsic regulator of chamber-specific heart development. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.19.444704.

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