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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis

Authors:
Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA
Citation:
J Am Soc Nephrol. 2021 Apr 28:ASN.2020101525. doi: 10.1681/ASN.2020101525. Online ahead of print
Epub:
Yes
Abstract:
Background: Podocytes are critical to maintaining the glomerular filtration barrier, and mutations in nephrotic syndrome genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Djenoune L, Tomar R, Dorison A, Ghobrial I, Schenk H, Hegermann J, Beverly-Staggs L, Hidalgo-Gonzalez A, Little MH, Drummond IA. Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis. J Am Soc Nephrol. 2021 Apr 28:ASN.2020101525. doi: 10.1681/ASN.2020101525. Online ahead of print.

The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system

Authors:
Carretero-Rodriguez L, Guðjónsdóttir R, Poparic I, Reilly ML, Chol M, Bianco IH, Chiapello M, Feret R, Deery MJ, Guthrie S
Citation:
J Neurosci. 2021;41(31):6652-6672. doi: 10.1523/JNEUROSCI.0983-19.2021. Online ahead of print
Epub:
Not Epub
Abstract:
A precise sequence of axon guidance events is required for the development of the ocular motor system. Three cranial nerves...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carretero-Rodriguez L, Guðjónsdóttir R, Poparic I, Reilly ML, Chol M, Bianco IH, Chiapello M, Feret R, Deery MJ, Guthrie S. The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system. J Neurosci. 2021;41(31):6652-6672. doi: 10.1523/JNEUROSCI.0983-19.2021. Online ahead of print.

Microinjection of Xenopus tropicalis Embryos

Authors:
Lane M, Mis EK, Khokha MK
Citation:
Cold Spring Harb Protoc. 2021 Jul 8. doi: 10.1101/pdb.prot107644. Online ahead of print
Epub:
Yes
Abstract:
Microinjection is an important technique used to study development in the oocyte and early embryo. In Xenopus, substances such...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Lane M, Mis EK, Khokha MK. Microinjection of Xenopus tropicalis Embryos. Cold Spring Harb Protoc. 2021 Jul 8. doi: 10.1101/pdb.prot107644. Online ahead of print.

Future Physiology 2020 (Virutal) Oral Communications: A zebrafish model of embryonic growth disruption reveals an ongoing impact on metabolic and cardiac phenotype

Authors:
Evans B
Citation:
Proc Physiol Soc. 2020;46:OC03
Epub:
Not Epub
Abstract:
As climate change continues to pose a global problem, the need to understand organisms immediate and ongoing responses to the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Evans B. Future Physiology 2020 (Virutal) Oral Communications: A zebrafish model of embryonic growth disruption reveals an ongoing impact on metabolic and cardiac phenotype. Proc Physiol Soc. 2020;46:OC03.

Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor

Authors:
Leventea E, Zhu Z, Fang X, Nikolaeva Y, Markham E, Hirst RA, van Eeden FJM, Malicki JJ
Citation:
https://www.pnas.org/content/118/28/e2102562118
Epub:
Not Epub
Abstract:
Here, we report that important regulators of cilia formation and ciliary compartment-directed protein transport function in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leventea E, Zhu Z, Fang X, Nikolaeva Y, Markham E, Hirst RA, van Eeden FJM, Malicki JJ. Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor. https://www.pnas.org/content/118/28/e2102562118.

Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

Authors:
Hahn I, Voelzmann A, Parkin J, Fuelle J, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A
Citation:
PLoS Genet. 2021;17(7):e1009647. doi:10.1371/journal.pgen.1009647
Epub:
Not Epub
Abstract:
The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hahn I, Voelzmann A, Parkin J, Fuelle J, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A. Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. PLoS Genet. 2021;17(7):e1009647. doi:10.1371/journal.pgen.1009647.

Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling

Authors:
Serifi I, Besta S, Karetsou Z, Giardoglou P, Beis D, Niewiadomski P, Papamarcaki T
Citation:
Sci Rep. 2021 Jul 6;11(1):13940. doi: 10.1038/s41598-021-93440-0
Epub:
Not Epub
Abstract:
The Hedgehog (Hh)/Gli signaling pathway controls cell proliferation and differentiation, is critical for the development of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serifi I, Besta S, Karetsou Z, Giardoglou P, Beis D, Niewiadomski P, Papamarcaki T. Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling. Sci Rep. 2021 Jul 6;11(1):13940. doi: 10.1038/s41598-021-93440-0.

The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line

Authors:
Hu X, Gao S, Wang P, Zhou Y, Chen K, Chen Q, Wang B, Hu W, Cheng P, Eid R, Giraud-Panis MJ, Wang L, Gilson E, Ye J, Lu Y.
Citation:
Biochimie. 2021 Jun 29:S0300-9084(21)00158-9. doi: 10.1016/j.biochi.2021.06.013. Online ahead of print
Epub:
Yes
Abstract:
Zebrafish is broadly used as a model organism in gene loss-of-function studies in vivo, but its employment in vitro is greatly...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: zebrafish lines
Citation Extract:
Hu X, Gao S, Wang P, Zhou Y, Chen K, Chen Q, Wang B, Hu W, Cheng P, Eid R, Giraud-Panis MJ, Wang L, Gilson E, Ye J, Lu Y.. The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line. Biochimie. 2021 Jun 29:S0300-9084(21)00158-9. doi: 10.1016/j.biochi.2021.06.013. Online ahead of print.

Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy

Authors:
Spreafico M, Cafora M, Bragato C, Capitanio D, Marasca F, Bodega B, De Palma C, Mora M, Gelfi C, Marozzi A, Pistocchi A
Citation:
Pharmacol Res. 2021;[Epub] doi:10.1016/j.phrs.2021.105750
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle degeneration and currently there are few therapeutic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Spreafico M, Cafora M, Bragato C, Capitanio D, Marasca F, Bodega B, De Palma C, Mora M, Gelfi C, Marozzi A, Pistocchi A. Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy. Pharmacol Res. 2021;[Epub] doi:10.1016/j.phrs.2021.105750.

Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes

Authors:
Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA
Citation:
J Dev Biol. 2021;9(3):25. doi:10.3390/jdb9030025
Epub:
Not Epub
Abstract:
Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA. Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR)...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA . Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes. J Dev Biol. 2021;9(3):25. doi:10.3390/jdb9030025.

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