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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Role of Ribosomal RNA Released from Red Cells in Blood Coagulation in Zebrafish and Humans
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Citation:
Blood Adv. 2021 Nov 23;5(22):4634-4647. doi: 10.1182/bloodadvances.2020003325. Epub:
Not Epub Abstract:
Hemolytic disorders are characterized by hemolysis and are prone to thrombosis. Previously, it has been shown that the RNA... Delivery Method:
zebrafish injection (piggyback Vivo-Morpholino + DNA) Organism or Cell Type:
zebrafish Citation Extract: Alharbi A, Iyer N, AlQaryoute A, Raman R, Burks D, Azad R, Jagadeeswaran P. Role of Ribosomal RNA Released from Red Cells in Blood Coagulation in Zebrafish and Humans. Blood Adv. 2021 Nov 23;5(22):4634-4647. doi: 10.1182/bloodadvances.2020003325. . |
Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease
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Citation:
Proc Nat Acad Sci USA. 2021;118(39):e2106770118. doi:10.1073/pnas.2106770118 Epub:
Not Epub Abstract:
Skeletal ciliopathies (e.g., Jeune syndrome, short rib polydactyly syndrome, and Sensenbrenner syndrome) are frequently... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis Citation Extract: Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS. Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. Proc Nat Acad Sci USA. 2021;118(39):e2106770118. doi:10.1073/pnas.2106770118. |
HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production
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Citation:
Exp Cell Res. 2021 Sep 18:112831. doi:10.1016/j.yexcr.2021.112831. Epub:
Not Epub Abstract:
Angiogenesis is the process by which new blood vessels form from preexisting vessels and regulates the processes of embryonic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang J, Chen Y, Zeng Z, Feng R, Wang Q, Zhang Q, Sun K, Chen AF, Lu Y, Yu Y. HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production. Exp Cell Res. 2021 Sep 18:112831. doi:10.1016/j.yexcr.2021.112831.. |
Cell-cell contact landscapes in Xenopus gastrula tissues
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Citation:
Proc Nat Acad Sci USA. 2021;118(39):e2107953118 [Epub] doi:10.1073/pnas.2107953118 Epub:
Yes Abstract:
Molecular and structural facets of cell-cell adhesion have been extensively studied in monolayered epithelia. Here, we perform... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Barua D, Nagel M, Winklbauer R. Cell-cell contact landscapes in Xenopus gastrula tissues. Proc Nat Acad Sci USA. 2021;118(39):e2107953118 [Epub] doi:10.1073/pnas.2107953118. |
Notch-mediated re-specification of neuronal identity during central nervous system development
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Citation:
Current Biology. 2021;[Epub] doi: 10.1016/j.cub.2021.08.049 Epub:
Not Epub Abstract:
Neuronal identity has long been thought of as immutable, so that once a cell acquires a specific fate, it is maintained for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Engerer P, Petridou E, Williams PR, Suzuki SC, Yoshimatsu T, Portugues R, Misgeld T, Godinho L. Notch-mediated re-specification of neuronal identity during central nervous system development. Current Biology. 2021;[Epub] doi: 10.1016/j.cub.2021.08.049. |
A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2
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Citation:
J Neurosci Methods. 2021;[Epub] doi:10.1016/j.jneumeth.2021.109357 Epub:
Not Epub Abstract:
Background: The GluA2 subunit of AMPA receptors (AMPARs) undergoes RNA editing at a specific base mediated by the enzyme ADAR2... Organism or Cell Type:
cell culture Citation Extract: Chaytow H, Hassan IS, Akbar S, Popplewell L, Dickson G, Chen PE. A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2. J Neurosci Methods. 2021;[Epub] doi:10.1016/j.jneumeth.2021.109357. |
Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5
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Citation:
Nat Commun. 2021;12(1):5482. doi:10.1038/s41467-021-25464-z Epub:
Not Epub Abstract:
Rotating cilia at the vertebrate left-right organizer (LRO) generate an asymmetric leftward flow, which is sensed by cells at... Delivery Method:
microinjection Organism or Cell Type:
Xenopus, zebrafish Citation Extract: Maerker M, Getwan M, Dowdle ME, McSheene JC, Gonzalez V, Pelliccia JL, Hamilton DS, Yartseva V, Vejnar C, Tingler M, Minegishi K, Vick P, Giraldez AJ, Hamada H, Burdine RD, Sheets MD, Blum M, Schweickert A. Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5. Nat Commun. 2021;12(1):5482. doi:10.1038/s41467-021-25464-z. |
Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain
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Citation:
PLoS Genet. 2021;17(9):e1009794. doi:10.1371/journal.pgen.1009794 Epub:
Not Epub Abstract:
LRRK2 gain-of-function is considered a major cause of Parkinson’s disease (PD) in humans. However, pathogenicity of LRRK2 loss-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M. Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain. PLoS Genet. 2021;17(9):e1009794. doi:10.1371/journal.pgen.1009794. |
CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression
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Citation:
Nat Commun. 2021 Sep 13;12(1):5415. doi: 10.1038/s41467-021-25604-5 Epub:
Not Epub Abstract:
Coordinated chromatin interactions between enhancers and promoters are critical for gene regulation. The architectural protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franke M, De la Calle-Mustienes E, Neto A, Almuedo-Castillo M, Irastorza-Azcarate I, Acemel RD, Tena JJ, Santos-Pereira JM, Gómez-Skarmeta JL. CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression. Nat Commun. 2021 Sep 13;12(1):5415. doi: 10.1038/s41467-021-25604-5. |
Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa
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Citation:
Gene Ther. 2021 Sep 14. doi: 10.1038/s41434-021-00291-5. Online ahead of print Epub:
Yes Abstract:
By combining next generation whole exome sequencing and induced pluripotent stem cell (iPSC) technology we found that an Alu... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tucker BA, Burnight ER, Cranston CM, Ulferts MJ, Luse MA, Westfall T, Scott CA, Marsden A, Gibson-Corley K, Wiley LA, Han IC, Slusarski DC, Mullins RF, Stone EM. Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa. Gene Ther. 2021 Sep 14. doi: 10.1038/s41434-021-00291-5. Online ahead of print. |