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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12153 scientific papers returned from the database with the search filters currently being used below.
There are 12153 scientific papers returned from the database with the search filters currently being used below.
Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes
Citation:
J Dev Biol. 2021;9(3):25. doi:10.3390/jdb9030025 Epub:
Not Epub Abstract:
Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA. Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR)... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mehdizadeh T, Majumdar HD, Ahsan S, Tavares ALP, Moody SA
. Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes. J Dev Biol. 2021;9(3):25. doi:10.3390/jdb9030025. |
Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis
Citation:
Genet Med. 2021;[Epub] doi:10.1038/s41436-021-01237-3 Epub:
Not Epub Abstract:
Purpose: Congenital hypothyroidism (CH) is a common congenital endocrine disorder in humans. CH-related diseases such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang R-M, Zhan M, Zhou Q-Y, Ye X-P, Wu F-Y, Dong M, Sun F, Fang Y, Zhang R-J, Zhang C-R, Yang L, Guo M-M, Zhang J-X, Liang J, Cheng F, Liu W, Han B, Zhou Y, Zhao S-X, Song H-D. Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis. Genet Med. 2021;[Epub] doi:10.1038/s41436-021-01237-3. |
LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy
Citation:
EMBO J. 2021 Jun 28:e107134. doi:10.15252/embj.2020107134. Online ahead of print. https://www.embopress.org/doi/full/10.15252/embj.2020107134 Epub:
Not Epub Abstract:
Long non-coding RNAs (lncRNAs) are emerging as key regulators of endothelial cell function. Here, we investigated the role of a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sehgal P, Mathew S, Sivadas A, Ray A, Tanwar J, Vishwakarma S, Ranjan G, Shamsudheen KV, Bhoyar RC, Pateria A, Leonard E, Lalwani M, Vats A, Pappuru RR, Tyagi M, Jakati S, Sengupta S, B K B, Chakrabarti S, Kaur I, Motiani RK, Scaria V, Sivasubbu S. LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy. EMBO J. 2021 Jun 28:e107134. doi:10.15252/embj.2020107134. Online ahead of print. https://www.embopress.org/doi/full/10.15252/embj.2020107134. |
Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning
Citation:
Nat Commun. 2021;12(1):4032. doi:10.1038/s41467-021-24346-8 Epub:
Not Epub Abstract:
In animals, body axis patterning is based on the concentration-dependent interpretation of graded morphogen signals, which... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Lebedeva T, Aman AJ, Graf T, Niedermoser I, Zimmermann B, Kraus Y, Schatka M, Demilly A, Technau U, Genikhovich G. Cnidarian-bilaterian comparison reveals the ancestral regulatory logic of the β-catenin dependent axial patterning. Nat Commun. 2021;12(1):4032. doi:10.1038/s41467-021-24346-8. |
Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification
Citation:
Sci Rep. 2021;11:13433. doi:10.1038/s41598-021-92824-6 Epub:
Not Epub Abstract:
The Wnt pathway activates target genes by controlling the β-catenin-T-cell factor (TCF) transcriptional complex during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reis AH, Sokol SY. Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification. Sci Rep. 2021;11:13433. doi:10.1038/s41598-021-92824-6. |
Utilizing Zebrafish Embryos to Reveal Disruptions in Dorsoventral Patterning
Citation:
Curr Protoc. 2021 Jun;1(6):e179. doi: 10.1002/cpz1.179 Epub:
Not Epub Abstract:
Dorsoventral (DV) patterning is a key landmark of embryonic development that is primarily regulated by bone morphogenetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dasgupta S, Cheng V, Volz DC. Utilizing Zebrafish Embryos to Reveal Disruptions in Dorsoventral Patterning. Curr Protoc. 2021 Jun;1(6):e179. doi: 10.1002/cpz1.179. |
Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure
Citation:
FASEB J. 2021;35:e21588. doi:10.1096/fj.202001712RR Epub:
Not Epub Abstract:
Ammonia is considered the main pathogenic toxin in hepatic encephalopathy (HE). However, the molecular mechanisms involved have... Delivery Method:
Vivo-Morpholino osmotic pump to frontal cortex Organism or Cell Type:
C57Bl6 mice Citation Extract: Hamdani EH, Popek M, Frontczak-Baniewicz M, Utheim TP, Albrecht J, Zielińska M, Chaudhry FA. Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure. FASEB J. 2021;35:e21588. doi:10.1096/fj.202001712RR. |
Defects of cohesin loader lead to bone dysplasia associated with transcriptional disturbance
Citation:
J Cell Physiol. 2021;[Epub] doi:doi.org/10.1002/jcp.30491 Epub:
Not Epub Abstract:
Cohesin loader nipped-B-like protein (Nipbl) is increasingly recognized for its important role in development and cancer.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gu W, Wang, Gu R,Ouyang H, Bao B, Zheng L, Xu B. Defects of cohesin loader lead to bone dysplasia associated with transcriptional disturbance. J Cell Physiol. 2021;[Epub] doi:doi.org/10.1002/jcp.30491. |
Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code
Citation:
Nucl Acids Res. 2021;gkab533[Epub] doi:10.1093/nar/gkab533 Epub:
Yes Abstract:
The specific recognition of splice signals at or near exon-intron junctions is not explained by their weak conservation and... Organism or Cell Type:
cell culture: HeLa Citation Extract: Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G. Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code. Nucl Acids Res. 2021;gkab533[Epub] doi:10.1093/nar/gkab533. |
The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
Citation:
Elife. 2021 Jun 21;10:e66143. doi: 10.7554/eLife.66143 Epub:
Not Epub Abstract:
The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gentile A, Bensimon-Brito A, Priya R, Maischein HM, Piesker J, Guenther S, Gunawan F, Stainier DY. The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression. Elife. 2021 Jun 21;10:e66143. doi: 10.7554/eLife.66143. |