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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Numb is required for optimal contraction of skeletal muscle
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.03.453960 Epub:
Not Epub Abstract:
Background: The role of Numb, a protein that is important for cell fate and development was investigated in adult skeletal... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: mouse primary myotubes Citation Extract: De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu X-H, Guo L, Zhang B, Ko F, Raczkowski AM, Bauman WA, Goulbourne CN, Zhao W, Brotto M, Cardozo CP. Numb is required for optimal contraction of skeletal muscle. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.03.453960. |
Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l
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Citation:
Proc Nat Acad Sci USA. 2021:118(36)e2104661118. doi:10.1073/pnas.2104661118 Epub:
Yes Abstract:
Toll-like receptor 4 (Tlr) interactor with leucine-rich repeats (Tril) functions as a Tlr coreceptor to mediate innate immunity... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Kim H-S, Green YS, Xie Y, Christian JL. Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l. Proc Nat Acad Sci USA. 2021:118(36)e2104661118. doi:10.1073/pnas.2104661118. |
Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase
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Citation:
Front Cardiovasc Med. 2021;8:1000. doi:10.3389/fcvm.2021.724846 Epub:
Not Epub Abstract:
Background: Mitochondrial aminoacyl-tRNA synthetases (mtARSs) catalyze the binding of specific amino acids to their cognate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y. Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase. Front Cardiovasc Med. 2021;8:1000. doi:10.3389/fcvm.2021.724846. |
Efficient Generation of Knock-In Zebrafish Models for Inherited Disorders Using CRISPR-Cas9 Ribonucleoprotein Complexes
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Citation:
Int J Mol Sci. 2021; 22(17):9429. doi:10.3390/ijms22179429 Epub:
Not Epub Abstract:
CRISPR-Cas9-based genome-editing is a highly efficient and cost-effective method to generate zebrafish loss-of-function alleles... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: de Vrieze E, de Bruijn SE, Reurink J, Broekman S, van de Riet V, Aben M, Kremer H, van Wijk E. Efficient Generation of Knock-In Zebrafish Models for Inherited Disorders Using CRISPR-Cas9 Ribonucleoprotein Complexes. Int J Mol Sci. 2021; 22(17):9429. doi:10.3390/ijms22179429. |
The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish
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Citation:
Aquac Fish. 2021;[Epub] doi:10.1016/j.aaf.2021.07.003 Epub:
Yes Abstract:
Epiboly, the coordinated spreading of the enveloping layer (EVL), the yolk syncytial layer (YSL) and the deep cells (DCs)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang X, Wu Z, Bu M, Hu R, Zhang X, Li W, Chen L. The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish. Aquac Fish. 2021;[Epub] doi:10.1016/j.aaf.2021.07.003. |
Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion
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Citation:
Int J Mol Sci. 2021;22(17):9324. doi:10.3390/ijms22179324 Epub:
Not Epub Abstract:
Neural crest (NC) cells are highly migratory cells that contribute to various vertebrate tissues, and whose migratory behaviors... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Grund A, Till K, Giehl K, Borchers A. Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion. Int J Mol Sci. 2021;22(17):9324. doi:10.3390/ijms22179324. |
Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish
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Citation:
Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329 Epub:
Not Epub Abstract:
Cilia are microtubule-based structures projecting from the cell surface that perform diverse biological functions. Ciliary... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu P, Xu J, Wang Y, Zhao C. Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish. Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329. |
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis
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Citation:
Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print Epub:
Yes Abstract:
Primary cilia extending from mother centrioles are essential for vertebrate development and homeostasis maintenance. Centriolar... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S. NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis. Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print. |
A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing
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Citation:
Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8 Epub:
Not Epub Abstract:
Hereditary non-polyposis colorectal cancer, now known as Lynch syndrome (LS) is one of the most common cancer predisposition... Delivery Method:
electroporation, Vivo-Morpholino Organism or Cell Type:
cell culture: human and murine fibroblasts, mice Citation Extract: Biswas K, Couillard M, Cavallone L, Burkett S, Stauffer S, Martin BK, Southon E, Reid S, Plona TM, Baugher RN, Mellott SD, Pike KM, Albaugh ME, Maedler-Kron C, Hamel N, Tessarollo L, Marcus V, Foulkes WD, Sharan SK. A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing. Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8. |
Function of chromatin modifier Hmgn1 during neural crest and craniofacial development
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Citation:
Genesis. 2021 Sep 3:e23447. doi: 10.1002/dvg.23447. Online ahead of print Epub:
Yes Abstract:
The neural crest is a dynamic embryonic structure that plays a major role in the formation of the vertebrate craniofacial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Ihewulezi C, Saint-Jeannet JP. Function of chromatin modifier Hmgn1 during neural crest and craniofacial development. Genesis. 2021 Sep 3:e23447. doi: 10.1002/dvg.23447. Online ahead of print. |