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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway

Authors:
Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y
Citation:
Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y. The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway. Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4.

Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues

Authors:
Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M
Citation:
microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481
Epub:
Not Epub
Abstract:
Cell behaviors such as survival, proliferation, and death are governed by a multitude of cues, both intrinsic and extrinsic. To...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M. Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues. microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481.

Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker

Authors:
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL
Citation:
BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z
Epub:
Not Epub
Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker. BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z.

Cell-Penetrating D-Peptides Retain Antisense Morpholino Oligomer Delivery Activity

Authors:
Schissel CK, Farquhar CE, Malmberg AB, Loas A, Pentelute BL
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.30.462617
Epub:
Not Epub
Abstract:
Cell-penetrating peptides (CPPs) can cross the cell membrane to enter the cytosol and deliver otherwise non-penetrant...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa 654
Citation Extract:
Schissel CK, Farquhar CE, Malmberg AB, Loas A, Pentelute BL. Cell-Penetrating D-Peptides Retain Antisense Morpholino Oligomer Delivery Activity. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.30.462617.

Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus

Authors:
Johansen MD, Alcaraz M, Dedrick RM, Roquet-Banères F, Hamela C, Hatfull GF, Kremer L
Citation:
Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16
Epub:
Not Epub
Abstract:
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansen MD, Alcaraz M, Dedrick RM, Roquet-Banères F, Hamela C, Hatfull GF, Kremer L. Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus. Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16.

Glypican 4 mediates Wnt transport between germ layers via signaling filopodia

Authors:
Hu B Rodriguez JJ Balaraju AK, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F
Citation:
J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082
Epub:
Not Epub
Abstract:
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu B Rodriguez JJ Balaraju AK, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican 4 mediates Wnt transport between germ layers via signaling filopodia. J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082.

The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway

Authors:
Sánchez-Sánchez AV, García-España A, Sánchez-Gómez P, Font-de-Mora J, Merino M, Mullor JL
Citation:
Int J Mol Sci. 2021;22(19):10620. doi:10.3390/ijms221910620
Epub:
Not Epub
Abstract:
NANOG is a key transcription factor required for maintaining pluripotency of embryonic stem cells. Elevated NANOG expression...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Sánchez-Sánchez AV, García-España A, Sánchez-Gómez P, Font-de-Mora J, Merino M, Mullor JL. The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway. Int J Mol Sci. 2021;22(19):10620. doi:10.3390/ijms221910620 .

Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera

Authors:
Poganik JR, Huang K-T, Parvez S, Zhao Y, Raja S, Long MJC, Aye Y
Citation:
Nat Comm. 2021;12(1):5736. doi:10.1038/s41467-021-25466-x
Epub:
Not Epub
Abstract:
Despite the emerging importance of reactive electrophilic drugs, deconvolution of their principal targets remains difficult....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poganik JR, Huang K-T, Parvez S, Zhao Y, Raja S, Long MJC, Aye Y. Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera. Nat Comm. 2021;12(1):5736. doi:10.1038/s41467-021-25466-x.

The microRNA miR-18a links proliferation and inflammation during photoreceptor regeneration in the injured zebrafish retina

Authors:
Magner E, Sandoval-Sanchez P, Kramer AC, Thummel R, Hitchcock PF, Taylor SM
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.25.441353
Epub:
Not Epub
Abstract:
In mammals, photoreceptor loss causes permanent blindness, but in zebrafish (Danio rerio), photoreceptor loss reprograms Muller...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Magner E, Sandoval-Sanchez P, Kramer AC, Thummel R, Hitchcock PF, Taylor SM. The microRNA miR-18a links proliferation and inflammation during photoreceptor regeneration in the injured zebrafish retina. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.25.441353 .

Germ cells are not essential for sexual dimorphism of gonads in common carp, C. carpio L

Authors:
Tao B, Liao X, Chen L, Li Y, Chen K, Jia S, Wu X, Ma W, Yunya Wu, Zhong W, Chen J, Song Y, Hu W
Citation:
Aquaculture. 2022;547:737501. doi:10.1016/j.aquaculture.2021.737501
Epub:
Not Epub
Abstract:
Common carp is the fourth most cultivated fish species in the world. Sexually dimorphic growth of common carp makes its sex...
Organism or Cell Type:
Cyprinus carpio (common carp)
Citation Extract:
Tao B, Liao X, Chen L, Li Y, Chen K, Jia S, Wu X, Ma W, Yunya Wu, Zhong W, Chen J, Song Y, Hu W. Germ cells are not essential for sexual dimorphism of gonads in common carp, C. carpio L. Aquaculture. 2022;547:737501. doi:10.1016/j.aquaculture.2021.737501.

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