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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis
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Citation:
Dev Dyn. 2022 Mar 9. doi: 10.1002/dvdy.467. Online ahead of print Epub:
Not Epub Abstract:
Background: Retinoblastoma-binding protein 4 (Rbbp4) is a component of transcription regulatory complexes that control cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schultz-Rogers LE, Thayer ML, Kambakam S, Wierson WA, Helmer JA, Wishman MD, Wall KA, Greig JL, Forsman JL, Puchhalapalli K, Nair S, Weiss TJ, Luiken JM, Blackburn PR, Ekker SC, Kool M, McGrail M. Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis. Dev Dyn. 2022 Mar 9. doi: 10.1002/dvdy.467. Online ahead of print. |
SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling
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Citation:
Oncogene. 2022;[Epub] doi:10.1038/s41388-022-02259-0 Epub:
Yes Abstract:
Breast cancer stem cells (BCSCs) are the main drivers of recurrence and metastasis. However, commonly used drugs rarely target... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rong Z, Zhang L, Li Z, Xiao Z, Duan Y, Ren X, Zi Y, Gao J, Mu Y, Guan Y, Cao Z, Wang X, Pei Q, Zeng Y, Fan Q, Zeng Z, Ou D, He J, Nie Y, Tan R, Weng L, Li Y, Xiang R, Deng Y, Sun L. SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling. Oncogene. 2022;[Epub] doi:10.1038/s41388-022-02259-0. |
Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth
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Citation:
Dev Cell. 2022 Mar 28;57(6):767-782.e6. doi: 10.1016/j.devcel.2022.02.015. Epub 2022 Mar 10. Epub:
Not Epub Abstract:
During embryogenesis, the initial vascular network forms by the process of vasculogenesis, or the specification of vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Metikala S, Warkala M, Chetty SC, Chestnut B, Florat DR, Plender E, Nester O, Koenig AL, Astrof S, Sumanas S. Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth. Dev Cell. 2022 Mar 28;57(6):767-782.e6. doi: 10.1016/j.devcel.2022.02.015. Epub 2022 Mar 10. . |
ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis
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Citation:
Cell Discov. 2022;8(1):25 doi:10.1038/s41421-022-00385-3 Epub:
Not Epub Abstract:
Primary cilia are antenna-like subcellular structures to act as signaling platforms to regulate many cellular processes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, Chang Y, Liu M, Xu Z, Huo C, Yan X, Yang Y, Liu W, Shu Q, Xie S, Zhou T. ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis. Cell Discov. 2022;8(1):25 doi:10.1038/s41421-022-00385-3. |
Electron Transfer Flavoprotein (ETF) α Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption
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Citation:
Oxid Med Cell Longev. 2022;2022:7969916 [Epub] doi:10.1155/2022/7969916 Epub:
Yes Abstract:
While impairment of vascular homeostasis induced by hypercholesterolemia is the first step of cardiovascular diseases, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan Y, Xu Y, Yang X, Li Z, Niu K, Liu C, Zhao M, Xiao Q,Wu W. Electron Transfer Flavoprotein (ETF) α Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption. Oxid Med Cell Longev. 2022;2022:7969916 [Epub] doi:10.1155/2022/7969916. |
Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis
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Citation:
Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y. PMID: 36859431; PMCID: PMC9977867 Epub:
Not Epub Abstract:
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Murayama E, Vivier C, Schmidt A, Herbomel P. Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis. Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y. PMID: 36859431; PMCID: PMC9977867. |
Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling
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Citation:
Nat Neurosci. 2022;25:280-4. doi:10.1038/s41593-022-01023-7 Epub:
Not Epub Abstract:
Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting additional roles of this cell... Organism or Cell Type:
zebrafish Citation Extract: Xiao Y, Petrucco L, Hoodless LJ, Portugues R, Czopka T. Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling. Nat Neurosci. 2022;25:280-4. doi:10.1038/s41593-022-01023-7. |
The Fibrillin-1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells
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Citation:
Cancer Commun (Lond). 2022 Mar 2. doi: 10.1002/cac2.12274. Online ahead of print Epub:
Yes Abstract:
Background: Chemotherapy resistance is a primary reason of ovarian cancer therapy failure; hence it is important to investigate... Organism or Cell Type:
zebrafish Citation Extract: Wang Z, Chen W, Zuo L, Xu M, Wu Y, Huang J, Zhang X, Li Y, Wang J, Chen J, Wang H, Sun H. The Fibrillin-1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells. Cancer Commun (Lond). 2022 Mar 2. doi: 10.1002/cac2.12274. Online ahead of print. |
The ciliary transition zone protein TMEM218 synergistically interacts with the NPHP module and its reduced dosage leads to a wide range of syndromic ciliopathies
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Citation:
Hum Mol Genet. 2022 Feb 6:ddac027. doi: 10.1093/hmg/ddac027. Online ahead of print Epub:
Not Epub Abstract:
Mutations in genes that lead to dysfunctional cilia can cause a broad spectrum of human disease phenotypes referred to as... Organism or Cell Type:
zebrafish Citation Extract: Epting D, Decker E, Ott E, Eisenberger T, Bader I, Bachmann N, Bergmann C. The ciliary transition zone protein TMEM218 synergistically interacts with the NPHP module and its reduced dosage leads to a wide range of syndromic ciliopathies. Hum Mol Genet. 2022 Feb 6:ddac027. doi: 10.1093/hmg/ddac027. Online ahead of print. |
Somite morphogenesis is required for axial blood vessel formation during zebrafish embryogenesis
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Citation:
eLife. 2022;11:e74821. doi:10.7554/eLife.74821 Epub:
Not Epub Abstract:
Angioblasts that form the major axial blood vessels of the dorsal aorta and cardinal vein migrate toward the embryonic midline... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paulissen E, Palmisano NJ, Waxman JS, Martin BL. Somite morphogenesis is required for axial blood vessel formation during zebrafish embryogenesis. eLife. 2022;11:e74821. doi:10.7554/eLife.74821. |