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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Cortisol and glucocorticoid receptor 2 regulate acid secretion in medaka (Oryzias latipes) larvae

Authors:
Lin CH, Hu HJ, Chuang HJ, Tsou YL, Hwang PP
Citation:
J Comp Physiol B. 2021 Jul 17. doi: 10.1007/s00360-021-01390-w. Online ahead of print
Epub:
Not Epub
Abstract:
Freshwater fish live in environments where pH levels fluctuate more than those in seawater. During acidic stress, the acid-base...
Link:
https://link.springer.com/article/10.1007%2Fs00360-021-01390-w
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Lin CH, Hu HJ, Chuang HJ, Tsou YL, Hwang PP. Cortisol and glucocorticoid receptor 2 regulate acid secretion in medaka (Oryzias latipes) larvae. J Comp Physiol B. 2021 Jul 17. doi: 10.1007/s00360-021-01390-w. Online ahead of print.

Morpholino-driven transcriptional blockade of Dkk-1 in experimental osteosarcoma inhibits bone damage and tumor expansion by multiple mechanisms

Authors:
Pan S, Cesarek M, Godoy C, Co C, Schindler C, Padilla K, Poole R, Dabney A, Gregory C
Citation:
Res Sq. 2021;[preprint] doi:10.21203/rs.3.rs-677459/v1
Epub:
Not Epub
Abstract:
Osteosarcoma (OS) is the most common primary bone malignancy. Chemotherapy plays an essential role in OS treatment, potentially...
Link:
https://www.researchsquare.com/article/rs-677459/v1
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: (RFP)-labeled MOSJ-Dkk1 murine osteochondral sarcoma line, xenograft in Foxn1-/Foxn1- mice
Citation Extract:
Pan S, Cesarek M, Godoy C, Co C, Schindler C, Padilla K, Poole R, Dabney A, Gregory C. Morpholino-driven transcriptional blockade of Dkk-1 in experimental osteosarcoma inhibits bone damage and tumor expansion by multiple mechanisms. Res Sq. 2021;[preprint] doi:10.21203/rs.3.rs-677459/v1.

SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy

Authors:
Boeckel J-N, Möbius-Winkler M, Müller M, Rebs S, Eger N, Schoppe L, Tappu R, Kokot KE, Kneuer JM, Gaul S, Bordalo DM, Lai A, Haas J, Ghanbari M, Drewe-Boss P, Liss M, Katus HA, Ohler U, Gotthardt M, Laufs U, Streckfuss-Bömeke K, Meder B
Citation:
Genomics Proteomics Bioinformatics. 2021;[Epub ahead of print] doi:10.1016/j.gpb.2021.01.006
Epub:
Yes
Abstract:
Alternative mRNA splicing is a fundamental process to increase the versatility of the genome. In humans, cardiac mRNA splicing...
Link:
https://www.sciencedirect.com/science/article/pii/S1672022921001467
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boeckel J-N, Möbius-Winkler M, Müller M, Rebs S, Eger N, Schoppe L, Tappu R, Kokot KE, Kneuer JM, Gaul S, Bordalo DM, Lai A, Haas J, Ghanbari M, Drewe-Boss P, Liss M, Katus HA, Ohler U, Gotthardt M, Laufs U, Streckfuss-Bömeke K, Meder B. SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy. Genomics Proteomics Bioinformatics. 2021;[Epub ahead of print] doi:10.1016/j.gpb.2021.01.006.

Cell adhesions link subcellular actomyosin dynamics to tissue scale force production during vertebrate convergent extension

Authors:
Huebner RJ, Weng S, Lee C, Sarıkaya S, Papoulas O, Cox RM, Marcotte EM, Wallingford JB
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.21.449290
Epub:
Not Epub
Abstract:
Axis extension is a fundamental biological process that shapes multicellular organisms. The design of an animal’s body plan is...
Link:
https://www.biorxiv.org/content/10.1101/2021.06.21.449290v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Huebner RJ, Weng S, Lee C, Sarıkaya S, Papoulas O, Cox RM, Marcotte EM, Wallingford JB. Cell adhesions link subcellular actomyosin dynamics to tissue scale force production during vertebrate convergent extension. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.21.449290 .

The atypical RNA-binding protein TAF15 regulates dorsoanterior neural development through diverse mechanisms in Xenopus tropicalis

Authors:
DeJong CS, Dichmann DS, Exner CRT, Xu Y, Harland RM
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.14.041913
Epub:
Not Epub
Abstract:
The FET family of atypical RNA-binding proteins includes Fused in sarcoma (Fus), Ewing’s sarcoma (EWS), and the TATA-binding...
Link:
https://www.biorxiv.org/content/10.1101/2021.06.14.041913v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
DeJong CS, Dichmann DS, Exner CRT, Xu Y, Harland RM. The atypical RNA-binding protein TAF15 regulates dorsoanterior neural development through diverse mechanisms in Xenopus tropicalis. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.14.041913 .

A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes

Authors:
Thomas C, Wetherall B, Levasseur D, Harris RJ, Kerridge ST, Higgins JMG, Davies OR, Madgwick S
Citation:
Nat Commun. 2021;12(1):4322. doi:10.1038/s41467-021-24554-2
Epub:
Not Epub
Abstract:
Successful cell division relies on the timely removal of key cell cycle proteins such as securin. Securin inhibits separase,...
Link:
https://www.nature.com/articles/s41467-021-24554-2
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Thomas C, Wetherall B, Levasseur D, Harris RJ, Kerridge ST, Higgins JMG, Davies OR, Madgwick S. A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes. Nat Commun. 2021;12(1):4322. doi:10.1038/s41467-021-24554-2.

Real time large scale in vivo observations by light-sheet microscopy reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord

Authors:
Andersen SSL
Citation:
arXiv. 2021;2107.05242v1 [preprint]
Epub:
Not Epub
Abstract:
Axonal growth and guidance at the ventral floor plate is here followed in vivo in real time at high resolution by light-sheet...
Link:
https://arxiv.org/abs/2107.05242
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Andersen SSL. Real time large scale in vivo observations by light-sheet microscopy reveal intrinsic synchrony, plasticity and growth cone dynamics of midline crossing axons at the ventral floor plate of the zebrafish spinal cord. arXiv. 2021;2107.05242v1 [preprint].

Glypican 4 regulates planar cell polarity of endoderm cells by controlling the localization of Cadherin 2

Authors:
Balaraju AK, Hu B, Rodriguez JJ, Murry M, Lin F
Citation:
Development. 2021 Jul 15;148(14):dev199421. doi: 10.1242/dev.199421. Epub 2021 Jul 12
Epub:
Not Epub
Abstract:
Noncanonical Wnt/planar cell polarity (Wnt/PCP) signaling has been implicated in endoderm morphogenesis. However, the...
Link:
https://journals.biologists.com/dev/article-abstract/148/14/dev199421/270869/Glypican-4-regulates-planar-cell-polarity-of
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Balaraju AK, Hu B, Rodriguez JJ, Murry M, Lin F. Glypican 4 regulates planar cell polarity of endoderm cells by controlling the localization of Cadherin 2. Development. 2021 Jul 15;148(14):dev199421. doi: 10.1242/dev.199421. Epub 2021 Jul 12.

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Authors:
Kreis J, Wielath FM, Vick P
Citation:
Biol Open. 2021 Jul 15;10(7):bio056887. doi: 10.1242/bio.056887. Epub 2021 Jul 12
Epub:
Not Epub
Abstract:
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling....
Link:
https://journals.biologists.com/bio/article/10/7/bio056887/270868/Rab7-is-required-for-mesoderm-patterning-and
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kreis J, Wielath FM, Vick P. Rab7 is required for mesoderm patterning and gastrulation in Xenopus. Biol Open. 2021 Jul 15;10(7):bio056887. doi: 10.1242/bio.056887. Epub 2021 Jul 12.

Temporal regulation of Pten is essential for retina regeneration in zebrafish

Authors:
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijithkumar V, Ramachandran R
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.09.451767
Epub:
Not Epub
Abstract:
Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after an acute injury. Retina regeneration...
Link:
https://www.biorxiv.org/content/10.1101/2021.07.09.451767v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijithkumar V, Ramachandran R. Temporal regulation of Pten is essential for retina regeneration in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.09.451767.

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