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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking
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Citation:
bioRxiv. 2021;[preprint]. doi:10.1101/2021.10.18.464707 Epub:
Not Epub Abstract:
The mechanism for embryonic dorsal-ventral (DV) symmetry breaking is idiosyncratic to the species, then converges on polarized... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Schatzberg D, Thomas CF, Reidy P, Hadyniak SE, Skidanova V, Lawton ML, Dojer L, Kitchloo S, Zuch DT, Bradham CA. V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking. bioRxiv. 2021;[preprint]. doi:10.1101/2021.10.18.464707. |
Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis
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Citation:
Nat Commun. 2021;12(1):6094. doi:10.1038/s41467-021-26234-7 Epub:
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Zygotic genome activation (ZGA) initiates regionalized transcription underlying distinct cellular identities. ZGA is dependent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg C-P, Galande S. Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nat Commun. 2021;12(1):6094. doi:10.1038/s41467-021-26234-7. |
NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice
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Citation:
Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print Epub:
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Maternal obesity is associated with multiple adverse reproductive outcomes, whereas the underlying molecular mechanisms are... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Wang H, Zhu S, Wu X, Liu Y, Ge J, Wang Q, Gu L. NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice. Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print. |
Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish
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Citation:
Front Cell Dev Biol. 2021 Oct 1;9:736960. doi: 10.3389/fcell.2021.736960. eCollection 2021 Epub:
Not Epub Abstract:
Von Willebrand A domain-containing protein 8 (VWA8), also named KIAA0564, is a poorly characterized, mitochondrial matrix-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Umair M, Farooq Khan M, Aldrees M, Nashabat M, Alhamoudi KM, Bilal M, Alyafee Y, Al Tuwaijri A, Aldarwish M, Al-Rumayyan A, Alkhalaf H, Wadaan MAM, Alfadhel M. Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish. Front Cell Dev Biol. 2021 Oct 1;9:736960. doi: 10.3389/fcell.2021.736960. eCollection 2021. |
Nucleolin loss-of-function leads to aberrant FGF signaling and craniofacial anomalies
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.14.460382 Epub:
Not Epub Abstract:
rRNA transcription and ribosome biogenesis are global processes required for growth and proliferation of all cells, yet... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dash S, Trainor PA. Nucleolin loss-of-function leads to aberrant FGF signaling and craniofacial anomalies. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.14.460382. |
The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.08.459391 Epub:
Not Epub Abstract:
Although thrombosis has been extensively studied using various animal models, however, our understanding of the underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ding Y, Li Y, Zhang CQ, Liu F. The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.08.459391. |
Lmo7 recruits myosin II heavy chain to induce apical constriction in Xenopus ectoderm
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443820 Epub:
Not Epub Abstract:
Apical constriction, or reduction of the apical domain, underlies many morphogenetic events during development, such as furrow... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Matsuda M, Chu C-W, Sokol SY. Lmo7 recruits myosin II heavy chain to induce apical constriction in Xenopus ectoderm. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443820. |
Admp regulates tail bending by controlling the intercalation of the ventral epidermis through myosin phosphorylation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.21.461063 Epub:
Not Epub Abstract:
Chordate tailbud embryos have similar morphological features, including a bending tail. A recent study revealed that the... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (C. intestinalis type A, ascidian) Citation Extract: Kogure YS, Muraoka H, Koizumi WC, Gelin-alessi R, Godard B, Heisenberg CP, Oka K, Hotta K. Admp regulates tail bending by controlling the intercalation of the ventral epidermis through myosin phosphorylation. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.21.461063. |
Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development
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Citation:
Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636 Epub:
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Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Lee NY, Kim Y, Choi H-S, Ismail T, Ryu H-Y, Cho D-H, Ryoo ZY, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development. Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636. |
Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish
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Citation:
Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217 Epub:
Not Epub Abstract:
Compensatory hepatocyte proliferation and other liver regenerative processes are activated to sustain normal physiological... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Chiang K-Y, Li Y-W, Li Y-H, Huang S-J, Wu C-L, Gong H-Y, Wu J-L. Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish. Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217. |