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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Amoeboid-like neuronal migration ensures correct horizontal cell layer formation in the developing vertebrate retina

Authors:
Amini R, Schlüßler R, Möllmert S, Bhatnagar A, Guck J, Norden C
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.15.464510
Epub:
Not Epub
Abstract:
As neurons are often born at positions different than where they ultimately function, neuronal migration is key to ensure...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amini R, Schlüßler R, Möllmert S, Bhatnagar A, Guck J, Norden C. Amoeboid-like neuronal migration ensures correct horizontal cell layer formation in the developing vertebrate retina. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.15.464510.

Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling

Authors:
Jacobs CT, Kejriwal A, Kocha KM, Jin KY, Huang P
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.25.465818
Epub:
Not Epub
Abstract:
During neural development, progenitor cells generate different types of neurons in specific time windows. Despite the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jacobs CT, Kejriwal A, Kocha KM, Jin KY, Huang P. Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.25.465818.

Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation

Authors:
Ahmed M, Kojima Y, Masai I
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.18.464758
Epub:
Not Epub
Abstract:
In the vertebrate retina, an interplay between retinal ganglion cells (RGCs), amacrine and bipolar cells establishes a synaptic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahmed M, Kojima Y, Masai I. Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.18.464758.

Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways

Authors:
Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS
Citation:
Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3
Epub:
Not Epub
Abstract:
The transcriptional effector SMAD4 is a core component of the TGF-β family signaling pathways. However, its role in vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS. Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways. Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3.

NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration

Authors:
Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F
Citation:
Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5
Epub:
Not Epub
Abstract:
Fish species, such as zebrafish (Danio rerio), can regenerate their appendages after amputation through the formation of a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5.

Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway

Authors:
Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S
Citation:
Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print
Epub:
Not Epub
Abstract:
In the context of obesity-induced adipose tissue inflammation, migration of macrophages and their polarization from...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Chattopadhyay D, Das S, Guria S, Basu S, Mukherjee S. Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNgamma-JAK2-STAT1 pathway. Biochem J. 2021 Nov 1:BCJ20210442. doi: 10.1042/BCJ20210442. Online ahead of print.

Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability

Authors:
Marchalot A, Horiot C, Lambert J-M, Carrion C, Oblet C, Pollet J, Cogné M, Moreau J, Laffleur B, Delpy L
Citation:
J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039.
Epub:
Not Epub
Abstract:
Background: Allergy regroups numerous complex and various diseases classified as IgE-dependent or non-dependent...
Delivery Method:
Vivo-Morpholino, peptide-linked
Organism or Cell Type:
cell culture: B cells, myeloma cells; InEps mice
Citation Extract:
Marchalot A, Horiot C, Lambert J-M, Carrion C, Oblet C, Pollet J, Cogné M, Moreau J, Laffleur B, Delpy L. Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability. J Allergy Clin Immunol. 2021 Nov 2;S0091-6749(21)01680-8. doi: 10.1016/j.jaci.2021.09.039..

Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish

Authors:
Jeong Y-M, Lee J-G, Cho H-J, Lee WS, Jeong J, Lee J-S
Citation:
Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883
Epub:
Not Epub
Abstract:
The failure of amyloid beta (Aβ) clearance is a major cause of Alzheimer’s disease, and the brain lymphatic systems play a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jeong Y-M, Lee J-G, Cho H-J, Lee WS, Jeong J, Lee J-S. Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish. Int J Molec Sci. 2021;22(21):11883. doi:10.3390/ijms222111883.

Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis

Authors:
Wu S, Chen K, Xu T, Ma K, Gao L, Fu C, Zhang W, Jing C, Ren C, Deng M, Chen Y, Zhou Y, Pan W, Jia X
Citation:
Front Cell Dev Biol. 2021 Oct 13;9:709923. doi: 10.3389/fcell.2021.709923
Epub:
Not Epub
Abstract:
Vertebrate erythropoiesis involves nuclear and chromatin condensation at the early stages of terminal differentiation, which is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu S, Chen K, Xu T, Ma K, Gao L, Fu C, Zhang W, Jing C, Ren C, Deng M, Chen Y, Zhou Y, Pan W, Jia X. Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis. Front Cell Dev Biol. 2021 Oct 13;9:709923. doi: 10.3389/fcell.2021.709923.

Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish

Authors:
Bühler A, Gahr BM, Park D-D, Bertozzi A, Boos A, Dalvoy M, Pott A, Oswald F, Kovall RA, Kühn B, Weidinger G, Rottbauer W, Just S
Citation:
PLoS Genet. 2021;17(11):e1009890. doi:10.1371/journal.pgen.1009890
Epub:
Not Epub
Abstract:
In contrast to mammals, the zebrafish maintains its cardiomyocyte proliferation capacity throughout adulthood. However, neither...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bühler A, Gahr BM, Park D-D, Bertozzi A, Boos A, Dalvoy M, Pott A, Oswald F, Kovall RA, Kühn B, Weidinger G, Rottbauer W, Just S. Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish. PLoS Genet. 2021;17(11):e1009890. doi:10.1371/journal.pgen.1009890.

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