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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Cell-cell contact landscapes in Xenopus gastrula tissues
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Citation:
Proc Nat Acad Sci USA. 2021;118(39):e2107953118 [Epub] doi:10.1073/pnas.2107953118 Epub:
Yes Abstract:
Molecular and structural facets of cell-cell adhesion have been extensively studied in monolayered epithelia. Here, we perform... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Barua D, Nagel M, Winklbauer R. Cell-cell contact landscapes in Xenopus gastrula tissues. Proc Nat Acad Sci USA. 2021;118(39):e2107953118 [Epub] doi:10.1073/pnas.2107953118. |
Notch-mediated re-specification of neuronal identity during central nervous system development
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Citation:
Current Biology. 2021;[Epub] doi: 10.1016/j.cub.2021.08.049 Epub:
Not Epub Abstract:
Neuronal identity has long been thought of as immutable, so that once a cell acquires a specific fate, it is maintained for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Engerer P, Petridou E, Williams PR, Suzuki SC, Yoshimatsu T, Portugues R, Misgeld T, Godinho L. Notch-mediated re-specification of neuronal identity during central nervous system development. Current Biology. 2021;[Epub] doi: 10.1016/j.cub.2021.08.049. |
A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2
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Citation:
J Neurosci Methods. 2021;[Epub] doi:10.1016/j.jneumeth.2021.109357 Epub:
Not Epub Abstract:
Background: The GluA2 subunit of AMPA receptors (AMPARs) undergoes RNA editing at a specific base mediated by the enzyme ADAR2... Organism or Cell Type:
cell culture Citation Extract: Chaytow H, Hassan IS, Akbar S, Popplewell L, Dickson G, Chen PE. A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2. J Neurosci Methods. 2021;[Epub] doi:10.1016/j.jneumeth.2021.109357. |
Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5
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Citation:
Nat Commun. 2021;12(1):5482. doi:10.1038/s41467-021-25464-z Epub:
Not Epub Abstract:
Rotating cilia at the vertebrate left-right organizer (LRO) generate an asymmetric leftward flow, which is sensed by cells at... Delivery Method:
microinjection Organism or Cell Type:
Xenopus, zebrafish Citation Extract: Maerker M, Getwan M, Dowdle ME, McSheene JC, Gonzalez V, Pelliccia JL, Hamilton DS, Yartseva V, Vejnar C, Tingler M, Minegishi K, Vick P, Giraldez AJ, Hamada H, Burdine RD, Sheets MD, Blum M, Schweickert A. Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5. Nat Commun. 2021;12(1):5482. doi:10.1038/s41467-021-25464-z. |
Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain
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Citation:
PLoS Genet. 2021;17(9):e1009794. doi:10.1371/journal.pgen.1009794 Epub:
Not Epub Abstract:
LRRK2 gain-of-function is considered a major cause of Parkinson’s disease (PD) in humans. However, pathogenicity of LRRK2 loss-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M. Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain. PLoS Genet. 2021;17(9):e1009794. doi:10.1371/journal.pgen.1009794. |
CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression
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Citation:
Nat Commun. 2021 Sep 13;12(1):5415. doi: 10.1038/s41467-021-25604-5 Epub:
Not Epub Abstract:
Coordinated chromatin interactions between enhancers and promoters are critical for gene regulation. The architectural protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franke M, De la Calle-Mustienes E, Neto A, Almuedo-Castillo M, Irastorza-Azcarate I, Acemel RD, Tena JJ, Santos-Pereira JM, Gómez-Skarmeta JL. CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression. Nat Commun. 2021 Sep 13;12(1):5415. doi: 10.1038/s41467-021-25604-5. |
Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa
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Citation:
Gene Ther. 2021 Sep 14. doi: 10.1038/s41434-021-00291-5. Online ahead of print Epub:
Yes Abstract:
By combining next generation whole exome sequencing and induced pluripotent stem cell (iPSC) technology we found that an Alu... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tucker BA, Burnight ER, Cranston CM, Ulferts MJ, Luse MA, Westfall T, Scott CA, Marsden A, Gibson-Corley K, Wiley LA, Han IC, Slusarski DC, Mullins RF, Stone EM. Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa. Gene Ther. 2021 Sep 14. doi: 10.1038/s41434-021-00291-5. Online ahead of print. |
N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.10.459675 Epub:
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Lack of oxygen (hypoxia and anoxia) is detrimental to cell function and survival and underlies many disease conditions. Hence,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Park JS, Gabel AM, Kang L, Canales B, Kassir P, Osei-Ntansah A, Tran ND, Viswanathan S, Lee Y-S, Brewster R. N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.10.459675. |
Myosin-1b interacts with UNC45A and controls intestinal epithelial morphogenesis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.09.459609 Epub:
Not Epub Abstract:
Vesicle trafficking and the establishment of apico-basal polarity are essential processes in epithelium morphogenesis. Myosin-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Revenu C, Parlato M, Rosello M, Duroure K, Duclaux-Loras R, Nicolle O, Prospéri M-T, Stoufflet J, Vougny J, Lebreton C, Lépine P, Michaux G, Cerf-Benssusan N, Coudrier E, Del Bene F. Myosin-1b interacts with UNC45A and controls intestinal epithelial morphogenesis. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.09.459609. |
The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
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Citation:
J Biol Chem. 2021 Sep 9:101184. doi: 10.1016/j.jbc.2021.101184. Online ahead of print Epub:
Not Epub Abstract:
The deubiquitinating enzyme USP37 is known to contribute to timely onset of S-phase and progression of mitosis. However, it is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Stromberg BR, Singh M, Torres AE, Burrows AC, Pal D, Insinna C, Rhee Y, Dickson AS, Westlake CJ, Summers MK. The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress. J Biol Chem. 2021 Sep 9:101184. doi: 10.1016/j.jbc.2021.101184. Online ahead of print. |