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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle

Authors:
Shiuchi T, Otsuka A, Shimizu N, Chikahisa S, Séi H
Citation:
Int J Mol Sci. 2021;22(19):10831. doi:10.3390/ijms221910831
Epub:
Not Epub
Abstract:
Circadian phase shifts in peripheral clocks induced by changes in feeding rhythm often result in insulin resistance. However,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Shiuchi T, Otsuka A, Shimizu N, Chikahisa S, Séi H. Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle. Int J Mol Sci. 2021;22(19):10831. doi:10.3390/ijms221910831.

The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos

Authors:
Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA
Citation:
Commun Biol. 2021;4:1158. doi:10.1038/s42003-021-02688-9
Epub:
Not Epub
Abstract:
The enpp ectonucleotidases regulate lipidic and purinergic signalling pathways by controlling the extracellular concentrations...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA. The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos. Commun Biol. 2021;4:1158. doi:10.1038/s42003-021-02688-9.

Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers

Authors:
López-Vidal EM, Schissel CK, Mohapatra S, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL
Citation:
JACS Au. 2021;[Epub] doi:10.1021/jacsau.1c00327
Epub:
Not Epub
Abstract:
Therapeutic macromolecules such as proteins and oligonucleotides can be highly efficacious but are often limited to...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa, mice
Citation Extract:
López-Vidal EM, Schissel CK, Mohapatra S, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers. JACS Au. 2021;[Epub] doi:10.1021/jacsau.1c00327.

Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish

Authors:
Paolini A, Fontana F, Pham VC, Rödel CJ, Abdelilah-Seyfried S
Citation:
Cell Rep. 2021 Oct 5;37(1):109782. doi: 10.1016/j.celrep.2021.109782
Epub:
Not Epub
Abstract:
In the zebrafish embryo, the onset of blood flow generates fluid shear stress on endocardial cells, which are specialized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paolini A, Fontana F, Pham VC, Rödel CJ, Abdelilah-Seyfried S. Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish. Cell Rep. 2021 Oct 5;37(1):109782. doi: 10.1016/j.celrep.2021.109782.

Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny

Authors:
Romanos M, Allio G, Roussigné M, Combres L, Escalas N, Soula C, Médevielle F, Steventon B, Trescases A, Bénazéraf B
Citation:
eLife. 2021;10:e66588 doi:10.7554/eLife.66588
Epub:
Not Epub
Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know...
Delivery Method:
electroporation
Organism or Cell Type:
Coturnix japonica (quail)
Citation Extract:
Romanos M, Allio G, Roussigné M, Combres L, Escalas N, Soula C, Médevielle F, Steventon B, Trescases A, Bénazéraf B. Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny. eLife. 2021;10:e66588 doi:10.7554/eLife.66588.

SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling

Authors:
Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani NF, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp H-J, Lappalainen P, Ivaska J
Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022
Epub:
Not Epub
Abstract:
Actin-rich cellular protrusions direct versatile biological processes from cancer cell invasion to dendritic spine development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani NF, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp H-J, Lappalainen P, Ivaska J. SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022.

The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration

Authors:
Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG
Citation:
Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940
Epub:
Not Epub
Abstract:
Warm-blooded vertebrates regenerate lost limbs and their parts in general much worse than fishes and amphibians. We previously...
Delivery Method:
microinjection, Vivo-Morpholino
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG. The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration. Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940.

The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway

Authors:
Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y
Citation:
Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y. The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway. Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4.

Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues

Authors:
Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M
Citation:
microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481
Epub:
Not Epub
Abstract:
Cell behaviors such as survival, proliferation, and death are governed by a multitude of cues, both intrinsic and extrinsic. To...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M. Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues. microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481.

Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker

Authors:
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL
Citation:
BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z
Epub:
Not Epub
Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker. BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z.

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