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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis
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Citation:
J Am Soc Nephrol. 2021 Nov;32(11):2777-2794. doi: 10.1681/ASN.2020121699 Epub:
Not Epub Abstract:
Background: Autoantibodies binding to podocyte antigens cause idiopathic membranous glomerulonephritis (iMGN). However, it... Organism or Cell Type:
zebrafish Citation Extract: Müller-Deile J, Sopel N, Ohs A, Rose V, Gröner M, Wrede C, Hegermann J, Daniel C, Amann K, Zahner G, Schiffer M. Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis. J Am Soc Nephrol. 2021 Nov;32(11):2777-2794. doi: 10.1681/ASN.2020121699. |
Lysosomal degradation of the maternal dorsal determinant Hwa safeguards dorsal body axis formation
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Citation:
EMBO Rep. 2021 Oct 15:e53185. doi: 10.15252/embr.202153185. Online ahead of print Epub:
Yes Abstract:
The Spemann and Mangold Organizer (SMO) is of fundamental importance for dorsal ventral body axis formation during vertebrate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Zhu X, Wang P, Wei J, Li Y, Zhai J, Zheng T, Tao Q. Lysosomal degradation of the maternal dorsal determinant Hwa safeguards dorsal body axis formation. EMBO Rep. 2021 Oct 15:e53185. doi: 10.15252/embr.202153185. Online ahead of print. |
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period
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Citation:
Front Immunol. 2021 Oct 12;12:763067. doi: 10.3389/fimmu.2021.763067. eCollection 2021 Epub:
Not Epub Abstract:
Uterine M1/M2 macrophages activation states undergo dynamic changes throughout pregnancy, and inappropriate macrophages... Delivery Method:
intrauterine injection Organism or Cell Type:
mice Citation Extract: Ji WH, Li DD, Wei DP, Gu AQ, Yang Y, Peng JP. Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period. Front Immunol. 2021 Oct 12;12:763067. doi: 10.3389/fimmu.2021.763067. eCollection 2021. |
Antisense oligonucleotide repress telomerase activity via manipulating alternative splicing or translation
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Citation:
Biochem Biophys Res Commun. 2021 Oct 21;582:118-124. doi: 10.1016/j.bbrc.2021.10.034. Online ahead of print Epub:
Not Epub Abstract:
Telomerase is a reverse transcriptase that catalyzes the addition of telomeric repeated DNA onto the 3' ends of linear... Organism or Cell Type:
cell culture: HEK 293T, HeLa cells Citation Extract: Zhou J, Li T, Geng X, Sui L, Wang F. Antisense oligonucleotide repress telomerase activity via manipulating alternative splicing or translation. Biochem Biophys Res Commun. 2021 Oct 21;582:118-124. doi: 10.1016/j.bbrc.2021.10.034. Online ahead of print. |
The development of shape. Modular control of growth in the lepidopteran forewing
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Citation:
J Exp Zool B Mol Dev Evol. 2021 Oct 28. doi:10.1002/jez.b.23101. Online ahead of print Epub:
Yes Abstract:
The mechanisms by which tissues and organs achieve their final size and shape during development are largely unknown. Although... Organism or Cell Type:
Junonia coenia (butterfly) Citation Extract: McKenna KZ, Nijhout HF. The development of shape. Modular control of growth in the lepidopteran forewing. J Exp Zool B Mol Dev Evol. 2021 Oct 28. doi:10.1002/jez.b.23101. Online ahead of print. |
Multifunctional Nanopolymers for Blood-Brain Barrier Delivery and Inhibition of Glioblastoma Growth through EGFR/EGFRvIII, c-Myc, and PD-1
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Citation:
Nanomaterials. 2021;11(11):2892. doi:10.3390/nano11112892 Epub:
Not Epub Abstract:
Glioblastoma (GBM) is the most prevalent primary brain cancer in the pediatric and adult population. It is known as an... Delivery Method:
nanoparticle Organism or Cell Type:
Xenograft GL261 (mouse glioblastoma) in mice Citation Extract: Patil R, Sun T, Rashid MH, Israel LL, Ramesh A, Davani S, Black KL, Ljubimov AV, Holler E, Ljubimova JY. Multifunctional Nanopolymers for Blood-Brain Barrier Delivery and Inhibition of Glioblastoma Growth through EGFR/EGFRvIII, c-Myc, and PD-1. Nanomaterials. 2021;11(11):2892. doi:10.3390/nano11112892. |
Small Molecule Control of Morpholino Antisense Oligonucleotide Function through Staudinger Reduction
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Citation:
J Am Chem Soc. 2021 Oct 27. doi: 10.1021/jacs.1c08723. Online ahead of print Epub:
Not Epub Abstract:
Conditionally activated, caged morpholino antisense agents (cMOs) are tools that enable the temporal and spatial investigation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Darrah K, Wesalo J, Lukasak B, Tsang M, Chen JK, Deiters A. Small Molecule Control of Morpholino Antisense Oligonucleotide Function through Staudinger Reduction. J Am Chem Soc. 2021 Oct 27. doi: 10.1021/jacs.1c08723. Online ahead of print. |
Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis
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Citation:
Cell Discov. 2021 Oct 26;7(1):98. doi: 10.1038/s41421-021-00332-8 Epub:
Not Epub Abstract:
The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang F, Zeng QY, Xu H, Xu AN, Liu DJ, Li NZ, Chen Y, Jin Y, Xu CH, Feng CZ, Zhang YL, Liu D, Liu N, Xie YY, Yu SH, Yuan H, Xue K, Shi JY, Liu TX, Xu PF, Zhao WL, Zhou Y, Wang L, Huang QH, Chen Z, Chen SJ, Zhou XL, Sun XJ. Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis. Cell Discov. 2021 Oct 26;7(1):98. doi: 10.1038/s41421-021-00332-8. |
Renadirsen, a Novel 2'OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo
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Citation:
Curr Issues Mol Biol. 2021 Sep 25;43(3):1267-1281. doi: 10.3390/cimb43030090 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease caused by out-of-frame or nonsense mutation in the... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Ito K, Takakusa H, Kakuta M, Kanda A, Takagi N, Nagase H, Watanabe N, Asano D, Goda R, Masuda T, Nakamura A, Onishi Y, Onoda T, Koizumi M, Takeshima Y, Matsuo M, Takaishi K. Renadirsen, a Novel 2'OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo. Curr Issues Mol Biol. 2021 Sep 25;43(3):1267-1281. doi: 10.3390/cimb43030090. |
The Ribosome Biogenesis Factor Ltv1 Is Essential for Digestive Organ Development and Definitive Hematopoiesis in Zebrafish
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Citation:
Front Cell Dev Biol. 2021 Oct 7;9:704730. doi: 10.3389/fcell.2021.704730. eCollection 2021 Epub:
Not Epub Abstract:
Ribosome biogenesis is a fundamental activity in cells. Ribosomal dysfunction underlies a category of diseases called... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang C, Huang R, Ma X, Chen J, Han X, Li L, Luo L, Ruan H, Huang H. The Ribosome Biogenesis Factor Ltv1 Is Essential for Digestive Organ Development and Definitive Hematopoiesis in Zebrafish. Front Cell Dev Biol. 2021 Oct 7;9:704730. doi: 10.3389/fcell.2021.704730. eCollection 2021. |